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7NDG
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BU of 7ndg by Molmil
Cryo-EM structure of the ternary complex between Netrin-1, Neogenin and Repulsive Guidance Molecule B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neogenin, ...
Authors:Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
Deposit date:2021-02-01
Release date:2021-03-31
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (5.98 Å)
Cite:Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling.
Cell, 184, 2021
7NE0
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BU of 7ne0 by Molmil
Structure of the ternary complex between Netrin-1, Repulsive-Guidance Molecule-B (RGMB) and Neogenin
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
Deposit date:2021-02-02
Release date:2021-03-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling.
Cell, 184, 2021
7NE1
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BU of 7ne1 by Molmil
Structure of the complex between Netrin-1 and its receptor Neogenin
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
Deposit date:2021-02-02
Release date:2021-03-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling.
Cell, 184, 2021
2VGE
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BU of 2vge by Molmil
Crystal structure of the C-terminal region of human iASPP
Descriptor: RELA-ASSOCIATED INHIBITOR
Authors:Robinson, R.A, Lu, X, Jones, E.Y, Siebold, C.
Deposit date:2007-11-12
Release date:2008-02-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical and Structural Studies of Aspp Proteins Reveal Differential Binding to P53, P63 and P73
Structure, 16, 2008
6QP7
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BU of 6qp7 by Molmil
Drosophila Semaphorin 2a
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Robinson, R.A, Rozbesky, D, Harlos, K, Siebold, C, Jones, E.Y.
Deposit date:2019-02-13
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning.
Nat Commun, 10, 2019
6QP8
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BU of 6qp8 by Molmil
Drosophila Semaphorin 2b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, ...
Authors:Robinson, R.A, Rozbesky, D, Harlos, K, Siebold, C, Jones, E.Y.
Deposit date:2019-02-13
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning.
Nat Commun, 10, 2019
7ZT8
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BU of 7zt8 by Molmil
Structure of E8 TCR in complex in human MR1 bound to 3FBA
Descriptor: 1,2-ETHANEDIOL, 3-methylbenzoic acid, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ...
Authors:Karuppiah, V, Srikannathasan, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT3
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BU of 7zt3 by Molmil
Structure of E8 TCR in complex in human MR1 K43A
Descriptor: Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, TCR alpha, ...
Authors:Karuppiah, V, Srikannathasan, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT2
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BU of 7zt2 by Molmil
Structure of E8 TCR in complex with human MR1 bound to 5-OP-RU
Descriptor: 1,2-ETHANEDIOL, 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, ...
Authors:Karuppiah, V, Srikannathasan, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT4
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BU of 7zt4 by Molmil
Structure of E8 TCR in complex with human MR1 bound to 6FP
Descriptor: 2-azanyl-6-methyl-3~{H}-pteridin-4-one, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
Authors:Karuppiah, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT5
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BU of 7zt5 by Molmil
Structure of E8 TCR in complex in human MR1 bound to 3FSA
Descriptor: 3-methanoyl-2-oxidanyl-benzoic acid, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
Authors:Karuppiah, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT9
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BU of 7zt9 by Molmil
Structure of E8 TCR in complex in human MR1 bound to 4FBA
Descriptor: 1,2-ETHANEDIOL, 4-METHYLBENZOIC ACID, Beta-2-microglobulin, ...
Authors:Karuppiah, V, Srikannathasan, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT7
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BU of 7zt7 by Molmil
Structure of E8 TCR in complex in human MR1 bound to 5FSA
Descriptor: 1,2-ETHANEDIOL, 2-hydroxy-5-methylbenzoic acid, Beta-2-microglobulin, ...
Authors:Karuppiah, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7NDU
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BU of 7ndu by Molmil
Gag:02 TCR in complex with HLA-E featuring a non-natural amino acid
Descriptor: Beta-2-microglobulin, Gag6V(276-284 H4C), HLA class I histocompatibility antigen, ...
Authors:Pengelly, R.J, Robinson, R.A.
Deposit date:2021-02-02
Release date:2022-01-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Eur.J.Immunol., 52, 2022
7NDT
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BU of 7ndt by Molmil
UL40:01 TCR in complex with HLA-E with a non-natural amino acid
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
Authors:Pengelly, R.J, Robinson, R.A.
Deposit date:2021-02-02
Release date:2022-01-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.999 Å)
Cite:Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Eur.J.Immunol., 52, 2022
7NDQ
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BU of 7ndq by Molmil
Gag:02 TCR in complex with HLA-E.
Descriptor: Beta-2-microglobulin, Gag6V, HLA class I histocompatibility antigen, ...
Authors:Pengelly, R.J, Robinson, R.A.
Deposit date:2021-02-02
Release date:2022-01-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Eur.J.Immunol., 52, 2022
6ZKX
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BU of 6zkx by Molmil
Crystal structure of InhA:01 TCR in complex with HLA-E (Y84C) bound to InhA (53-61 GCG)
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ...
Authors:Srikannathasan, V, Karuppiah, V, Robinson, R.A.
Deposit date:2020-06-30
Release date:2022-01-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Eur.J.Immunol., 52, 2022
6ZKY
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BU of 6zky by Molmil
Crystal structure of InhA:01 TCR in complex with HLA-E (S147C) bound to InhA (53-61 H3C)
Descriptor: Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], HLA class I histocompatibility antigen, ...
Authors:Srikannathasan, V, Karuppiah, V, Robinson, R.A.
Deposit date:2020-06-30
Release date:2022-01-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Eur.J.Immunol., 52, 2022
6ZKZ
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BU of 6zkz by Molmil
Crystal structure of InhA:01 TCR in complex with HLA-E (F116C) bound to InhA (53-61 H4C)
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ...
Authors:Srikannathasan, V, Karuppiah, V, Robinson, R.A.
Deposit date:2020-06-30
Release date:2022-01-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Eur.J.Immunol., 52, 2022
6ZKW
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BU of 6zkw by Molmil
Crystal structure of InhA:01 TCR in complex with HLA-E bound to InhA (53-61)
Descriptor: Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], HLA class I histocompatibility antigen, ...
Authors:Srikannathasan, V, Karuppiah, V, Robinson, R.A.
Deposit date:2020-06-30
Release date:2022-01-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Eur.J.Immunol., 52, 2022
6QP9
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BU of 6qp9 by Molmil
Drosophila Semaphorin 1a, extracellular domains 1-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin-1A
Authors:Rozbesky, D, Robinson, R.A, Harlos, K, Siebold, C, Jones, E.Y.
Deposit date:2019-02-13
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning.
Nat Commun, 10, 2019
6RSY
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BU of 6rsy by Molmil
The complex between TCR a7b2 and human Class I MHC HLA-A0201-WT1 with the bound RMFPNAPYL peptide.
Descriptor: 1,2-ETHANEDIOL, ARG-MET-PHE-PRO-ASN-ALA-PRO-TYR-LEU, Beta-2-microglobulin, ...
Authors:Srikannathasan, V, Robinson, R.A.
Deposit date:2019-05-22
Release date:2020-04-15
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA.
J.Clin.Invest., 130, 2020
3OKT
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BU of 3okt by Molmil
Mouse Plexin A2, extracellular domains 1-4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Janssen, B.J.C, Robinson, R.A, Bell, C.H, Siebold, C, Jones, E.Y.
Deposit date:2010-08-25
Release date:2010-10-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.296 Å)
Cite:Structural basis of semaphorin-plexin signalling.
Nature, 467, 2010
3OKW
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BU of 3okw by Molmil
Mouse Semaphorin 6A, extracellular domains 1-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ...
Authors:Janssen, B.J.C, Robinson, R.A, Bell, C.H, Siebold, C, Jones, E.Y.
Deposit date:2010-08-25
Release date:2010-10-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Structural basis of semaphorin-plexin signalling.
Nature, 467, 2010
3OL2
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BU of 3ol2 by Molmil
Receptor-ligand structure of Human Semaphorin 4D with Plexin B1.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-B1, ...
Authors:Janssen, B.J.C, Robinson, R.A, Perez-Branguli, F, Bell, C.H, Mitchell, C.J, Siebold, C, Jones, E.Y.
Deposit date:2010-08-25
Release date:2010-10-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural basis of semaphorin-plexin signalling.
Nature, 467, 2010

 

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