Author results

1P9R
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CRYSTAL STRUCTURE OF VIBRIO CHOLERAE PUTATIVE NTPASE EPSE
Descriptor:General secretion pathway protein E, ZINC ION, CHLORIDE ION
Authors:Robien, M.A., Krumm, B.E., Sandkvist, M., Hol, W.G.J.
Deposit date:2003-05-12
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the extracellular protein secretion NTPase EpsE of Vibrio cholerae
J.Mol.Biol., 333, 2003
1P9W
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CRYSTAL STRUCTURE OF VIBRIO CHOLERAE PUTATIVE NTPASE EPSE
Descriptor:General secretion pathway protein E, ZINC ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Robien, M.A., Krumm, B.E., Sandkvist, M., Hol, W.G.J.
Deposit date:2003-05-12
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the extracellular protein secretion NTPase EpsE of Vibrio cholerae
J.Mol.Biol., 333, 2003
1RL4
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PLASMODIUM FALCIPARUM PEPTIDE DEFORMYLASE COMPLEX WITH INHIBITOR
Descriptor:formylmethionine deformylase, COBALT (II) ION, (2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID, ...
Authors:Robien, M.A., Nguyen, K.T., Kumar, A., Hirsh, I., Turley, S., Pei, D., Hol, W.G.J.
Deposit date:2003-11-24
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:An improved crystal form of Plasmodium falciparum peptide deformylase.
Protein Sci., 13, 2004
1RQC
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CRYSTALS OF PEPTIDE DEFORMYLASE FROM PLASMODIUM FALCIPARUM WITH TEN SUBUNITS PER ASYMMETRIC UNIT REVEAL CRITICAL CHARACTERISTICS OF THE ACTIVE SITE FOR DRUG DESIGN
Descriptor:formylmethionine deformylase, COBALT (II) ION
Authors:Robien, M.A., Nguyen, K.T., Kumar, A., Hirsh, I., Turley, S., Pei, D., Hol, W.G.
Deposit date:2003-12-04
Release date:2004-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An improved crystal form of Plasmodium falciparum peptide deformylase
Protein Sci., 13, 2004
1SYR
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INITIAL STRUCTURAL ANALYSIS OF PLASMODIUM FALCIPARUM THIOREDOXIN
Descriptor:thioredoxin
Authors:Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-04-01
Release date:2004-04-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Initial Structural Analysis of Plasmodium falciparum thioredoxin
To be Published
1TC5
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STRUCTURAL ANALYSIS OF A PROBABLE EUKARYOTIC D-AMINO ACID TRNA DEACYLASE
Descriptor:Probable eukaryotic D-amino acid tRNA deacylase, LMAJ005534AAA
Authors:Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-05-20
Release date:2004-06-08
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural analysis of LMAJ005534AAA, a probable eukaryotic D-amino acid tRNA deacylase from Leishmania major
To be Published
1XIQ
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PLASMODIUM FALCIPARUM NUCLEOSIDE DIPHOSPHATE KINASE B
Descriptor:Nucleoside diphosphate kinase B
Authors:Robien, M.A., Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-09-21
Release date:2004-10-12
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of Nucleoside diphosphate kinase B from Plasmodium falciparum
To be Published
1XTP
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STRUCTURAL ANALYSIS OF LEISHMANIA MAJOR LMAJ004091AAA, A SAM-DEPENDENT METHYLTRANSFERASE OF THE DUF858/PFAM05891 FAMILY
Descriptor:LMAJ004091AAA, S-ADENOSYL-L-HOMOSELENOCYSTEINE
Authors:Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-10-22
Release date:2004-11-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural Analysis of Leishmania major LMAJ004091AAA
To be Published
1Y1X
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STRUCTURAL ANALYSIS OF A HOMOLOG OF PROGRAMMED CELL DEATH 6 PROTEIN FROM LEISHMANIA MAJOR FRIEDLIN
Descriptor:Leishmania Major Homolog of Programmed Cell Death 6 Protein, CALCIUM ION, SULFATE ION
Authors:Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-11-19
Release date:2004-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural analysis of a homolog of programmed cell death 6 protein from Leishmania major Friedlin
To be Published
1Y63
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INITIAL CRYSTAL STRUCTURAL ANALYSIS OF A PROBABLE KINASE FROM LEISHMANIA MAJOR FRIEDLIN
Descriptor:Lmaj004144AAA protein, MANGANESE (II) ION, BROMIDE ION, ...
Authors:Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-12-03
Release date:2005-01-04
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structural analysis of a probable kinase from Leishmania major Friedlin
To be Published
1YJ8
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INITIAL STRUCTURAL ANALYSIS OF PLASMODIUM FALCIPARUM GLYCEROL-3-PHOSPHATE DEHYDROGENASE
Descriptor:glycerol-3-phosphate dehydrogenase
Authors:Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-01-13
Release date:2005-02-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Initial structural analysis of Plasmodium falciparum Glycerol-3-phosphate dehydrogenase
To be Published
2B30
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INITIAL CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF A PUTATIVE HAD/COF-LIKE HYDROLASE FROM PLASMODIUM VIVAX
Descriptor:Pvivax hypothetical protein, CALCIUM ION, CHLORIDE ION
Authors:Robien, M.A., Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-09-19
Release date:2005-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Initial Crystallographic Structural Analysis of a putative HAD/COF-like hydrolase from Plasmodium vivax
To be Published
2B4R
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CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM PLASMODIUM FALCIPARUM AT 2.25 ANGSTROM RESOLUTION REVEALS INTRIGUING EXTRA ELECTRON DENSITY IN THE ACTIVE SITE
Descriptor:glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, ...
Authors:Robien, M.A., Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-09-26
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site
Proteins, 62, 2006
2B4T
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CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM PLASMODIUM FALCIPARUM AT 2.25 ANGSTROM RESOLUTION REVEALS INTRIGUING EXTRA ELECTRON DENSITY IN THE ACTIVE SITE
Descriptor:glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
Authors:Robien, M.A., Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-09-26
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site
Proteins, 62, 2006
2B94
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STRUCTURAL ANALYSIS OF P KNOWLESI HOMOLOG OF P FALCIPARUM PNP
Descriptor:purine nucleoside phosphorylase, THIOSULFATE
Authors:Robien, M.A., Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-10-10
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural analysis of P knowlesi homolog of P falciparum PNP
To be Published
1BAL
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE E3-BINDING DOMAIN OF THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE CORE FROM THE 2-OXOGLUTARATE DEHYDROGENASE MULTIENZYME COMPLEX OF (ESCHERICHIA COLI)
Descriptor:DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE
Authors:Clore, G.M., Robien, M.A., Gronenborn, A.M.
Deposit date:1992-02-20
Release date:1994-01-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli.
Biochemistry, 31, 1992
1BBL
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE E3-BINDING DOMAIN OF THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE CORE FROM THE 2-OXOGLUTARATE DEHYDROGENASE MULTIENZYME COMPLEX OF ESCHERICHIA COLI
Descriptor:DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE
Authors:Clore, G.M., Robien, M.A., Gronenborn, A.M.
Deposit date:1992-02-20
Release date:1994-01-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli.
Biochemistry, 31, 1992
1SQ6
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PLASMODIUM FALCIPARUM HOMOLOG OF URIDINE PHOSPHORYLASE/PURINE NUCLEOSIDE PHOSPHORYLASE
Descriptor:uridine phosphorylase, putative, SULFATE ION
Authors:Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-03-17
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine.
Acta Crystallogr.,Sect.D, 61, 2005
1SVV
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INITIAL STUCTURAL ANALYSIS OF LEISHMANIA MAJOR THREONINE ALDOLASE
Descriptor:THREONINE ALDOLASE, UNKNOWN LIGAND
Authors:Hol, W.G.J., Robien, M.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-03-30
Release date:2004-08-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Initial Structural Analysis of Leishmania major Threonine Aldolase
To be Published
1X6O
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STRUCTURAL ANALYSIS OF LEISHMANIA BRAZILIENSIS EUKARYOTIC INITIATION FACTOR 5A
Descriptor:eukaryotic initiation factor 5a, DI(HYDROXYETHYL)ETHER
Authors:Bosch, J., Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-08-11
Release date:2004-08-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Analysis of Leishmania braziliensis eukaryotic initiation factor 5a
To be Published
2A0K
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CRYSTAL STRUCTURE OF NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE FROM TRYPANOSOMA BRUCEI AT 1.8 A RESOLUTION
Descriptor:Nucleoside 2-deoxyribosyltransferase, SULFATE ION, GLYCEROL
Authors:Bosch, J., Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-06-16
Release date:2005-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49, 2006
2F2T
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CRYSTAL STRUCTURE OF NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE FROM TRYPANOSOMA BRUCEI AT 1.7 A RESOLUTION WITH 5-AMINOISOQUINOLINE BOUND
Descriptor:Nucleoside 2-deoxyribosyltransferase, SULFATE ION, ISOQUINOLIN-5-AMINE, ...
Authors:Bosch, J., Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-11-17
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49, 2006
2F62
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CRYSTAL STRUCTURE OF NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE FROM TRYPANOSOMA BRUCEI AT 1.5 A RESOLUTION WITH (2-ETHYLPHENYL)METHANOL BOUND
Descriptor:Nucleoside 2-deoxyribosyltransferase, SULFATE ION, (2-ETHYLPHENYL)METHANOL, ...
Authors:Bosch, J., Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-11-28
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49, 2006
2F64
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CRYSTAL STRUCTURE OF NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE FROM TRYPANOSOMA BRUCEI AT 1.6 A RESOLUTION WITH 1-METHYLQUINOLIN-2(1H)-ONE BOUND
Descriptor:Nucleoside 2-deoxyribosyltransferase, SULFATE ION, 1-METHYLQUINOLIN-2(1H)-ONE, ...
Authors:Bosch, J., Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-11-28
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49, 2006
2F67
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CRYSTAL STRUCTURE OF NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE FROM TRYPANOSOMA BRUCEI AT 1.6 A RESOLUTION WITH BENZO[CD]INDOL-2(1H)-ONE BOUND
Descriptor:Nucleoside 2-deoxyribosyltransferase, SULFATE ION, BENZO[CD]INDOL-2(1H)-ONE, ...
Authors:Bosch, J., Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-11-28
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49, 2006
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