4MX1
 
 | | Structure of ricin A chain bound with 2-amino-4-oxo-N-(2-(3-phenylureido)ethyl)-3,4-dihydropteridine-7-carboxamide | | Descriptor: | 2-amino-4-oxo-N-{2-[(phenylcarbamoyl)amino]ethyl}-3,4-dihydropteridine-7-carboxamide, MALONIC ACID, Ricin A chain, ... | | Authors: | Robertus, J.D, Wiget, P.A, Manzano, L.A, Pruet, J.M, Gao, G, Saito, R, Jasheway, K.R, Monzingo, A.F, Anslyn, E.V. | | Deposit date: | 2013-09-25 | | Release date: | 2014-01-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics.
Bioorg.Med.Chem.Lett., 23, 2013
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4HV3
 | | Structure of Ricin A chain bound with N-(N-(pterin-7-yl)carbonyl-L-serinyl)-L-tryptophan | | Descriptor: | (2S)-2-[[(2S)-2-[(2-azanyl-4-oxidanylidene-1H-pteridin-7-yl)carbonylamino]-3-oxidanyl-propanoyl]amino]-3-(1H-indol-3-yl)propanoic acid, MALONIC ACID, Ricin, ... | | Authors: | Robertus, J.D, Manzano, L.A, Jasheway, K.R, Monzingo, A.F, Saito, R, Pruet, J.M, Wiget, P.A, Anslyn, E.V. | | Deposit date: | 2012-11-05 | | Release date: | 2012-12-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Peptide-conjugated pterins as inhibitors of ricin toxin A.
J.Med.Chem., 56, 2013
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2AAI
 | | Crystallographic refinement of ricin to 2.5 Angstroms | | Descriptor: | RICIN (A CHAIN), RICIN (B CHAIN), alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Rutenber, E, Katzin, B.J, Montfort, W, Villafranca, J.E, Ernst, S.R, Collins, E.J, Mlsna, D, Monzingo, A.F, Ready, M.P, Robertus, J.D. | | Deposit date: | 1993-09-07 | | Release date: | 1994-01-31 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystallographic refinement of ricin to 2.5 A.
Proteins, 10, 1991
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1BR6
 | | RICIN A CHAIN (RECOMBINANT) COMPLEX WITH PTEROIC ACID | | Descriptor: | PROTEIN (RICIN), PTEROIC ACID | | Authors: | Hollis, T, Yan, X, Svinth, M, Day, P, Monzingo, A.F, Milne, G.W.A, Robertus, J.D. | | Deposit date: | 1998-08-27 | | Release date: | 1998-09-02 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure-based identification of a ricin inhibitor.
J.Mol.Biol., 266, 1997
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1BR5
 | | RICIN A CHAIN (RECOMBINANT) COMPLEX WITH NEOPTERIN | | Descriptor: | NEOPTERIN, PROTEIN (RICIN) | | Authors: | Day, P, Yan, X, Hollis, T, Svinth, M, Monzingo, A.F, Milne, G.W.A, Robertus, J.D. | | Deposit date: | 1998-08-26 | | Release date: | 1998-09-02 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure-based identification of a ricin inhibitor.
J.Mol.Biol., 266, 1997
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2BAA
 | | THE REFINED CRYSTAL STRUCTURE OF AN ENDOCHITINASE FROM HORDEUM VULGARE L. SEEDS TO 1.8 ANGSTROMS RESOLUTION | | Descriptor: | ENDOCHITINASE (26 KD) | | Authors: | Hart, P.J, Pfluger, H.D, Monzingo, A.F, Ready, M.P, Ernst, S.R, Hollis, T, Robertus, J.D. | | Deposit date: | 1995-01-26 | | Release date: | 1996-01-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The refined crystal structure of an endochitinase from Hordeum vulgare L. seeds at 1.8 A resolution.
J.Mol.Biol., 248, 1995
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4ESI
 | | Structure of ricin A chain bound with N-((1H-1,2,3-triazol-4-yl)methyl-2-amino-4-oxo-3,4-dihydropteridine-7-carboxamide | | Descriptor: | 2-amino-4-oxo-N-(1H-1,2,3-triazol-5-ylmethyl)-1,4-dihydropteridine-7-carboxamide, Ricin | | Authors: | Jasheway, K.R, Pruet, J.M, Ryoto, S, Manzano, L.A, Wiget, P.A, Kamat, I, Anslyn, E.V, Monzingo, A.F, Robertus, J.D. | | Deposit date: | 2012-04-23 | | Release date: | 2012-10-31 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Optimized 5-membered heterocycle-linked pterins for the inhibition of Ricin Toxin A.
ACS Med Chem Lett, 3, 2012
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1D2K
 | | C. IMMITIS CHITINASE 1 AT 2.2 ANGSTROMS RESOLUTION | | Descriptor: | CHITINASE 1 | | Authors: | Hollis, T, Monzingo, A.F, Bortone, K, Ernst, S.R, Cox, R, Robertus, J.D. | | Deposit date: | 1999-09-23 | | Release date: | 2000-09-27 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The X-ray structure of a chitinase from the pathogenic fungus Coccidioides immitis.
Protein Sci., 9, 2000
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1CHK
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2IDR
 | | Crystal structure of translation initiation factor EIF4E from wheat | | Descriptor: | Eukaryotic translation initiation factor 4E-1 | | Authors: | Monzingo, A.F, Sadow, J, Dhaliwal, S, Lyon, A, Hoffman, D.W, Robertus, J.D, Browning, K.S. | | Deposit date: | 2006-09-15 | | Release date: | 2007-06-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond.
Plant Physiol., 143, 2007
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2IDV
 | | Crystal structure of wheat C113S mutant EIF4E bound TO 7-methyl-GDP | | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic translation initiation factor 4E-1 | | Authors: | Monzingo, A.F, Dutt-Chaudhuri, A, Sadow, J, Dhaliwal, S, Hoffman, D.W, Robertus, J.D, Browning, K.S. | | Deposit date: | 2006-09-15 | | Release date: | 2007-06-12 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond.
Plant Physiol., 143, 2007
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1SBT
 | | ATOMIC COORDINATES FOR SUBTILISIN BPN (OR NOVO) | | Descriptor: | SUBTILISIN BPN' | | Authors: | Alden, R.A, Birktoft, J.J, Kraut, J, Robertus, J.D, Wright, C.S. | | Deposit date: | 1972-08-11 | | Release date: | 1977-01-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Atomic coordinates for subtilisin BPN' (or Novo).
Biochem.Biophys.Res.Commun., 45, 1971
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1PAF
 | | THE 2.5 ANGSTROMS STRUCTURE OF POKEWEED ANTIVIRAL PROTEIN | | Descriptor: | POKEWEED ANTIVIRAL PROTEIN | | Authors: | Monzingo, A.F, Collins, E.J, Ernst, S.R, Irvin, J.D, Robertus, J.D. | | Deposit date: | 1992-10-19 | | Release date: | 1994-01-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The 2.5 A structure of pokeweed antiviral protein.
J.Mol.Biol., 233, 1993
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1PAG
 | | THE 2.5 ANGSTROMS STRUCTURE OF POKEWEED ANTIVIRAL PROTEIN | | Descriptor: | FORMYCIN-5'-MONOPHOSPHATE, POKEWEED ANTIVIRAL PROTEIN | | Authors: | Monzingo, A.F, Collins, E.J, Ernst, S.R, Irvin, J.D, Robertus, J.D. | | Deposit date: | 1992-10-19 | | Release date: | 1994-01-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The 2.5 A structure of pokeweed antiviral protein.
J.Mol.Biol., 233, 1993
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1RTC
 | | THE STRUCTURE OF RECOMBINANT RICIN A CHAIN AT 2.3 ANGSTROMS | | Descriptor: | RICIN | | Authors: | Mlsna, D, Monzingo, A.F, Katzin, B.J, Ernst, S, Robertus, J.D. | | Deposit date: | 1992-10-29 | | Release date: | 1993-10-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of recombinant ricin A chain at 2.3 A.
Protein Sci., 2, 1993
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1CHG
 | | CHYMOTRYPSINOGEN,2.5 ANGSTROMS CRYSTAL STRUCTURE, COMPARISON WITH ALPHA-CHYMOTRYPSIN,AND IMPLICATIONS FOR ZYMOGEN ACTIVATION | | Descriptor: | CHYMOTRYPSINOGEN A | | Authors: | Freer, S.T, Kraut, J, Robertus, J.D, Wright, H.T, Xuong, N.H. | | Deposit date: | 1975-03-01 | | Release date: | 1976-11-22 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Chymotrypsinogen: 2.5-angstrom crystal structure, comparison with alpha-chymotrypsin, and implications for zymogen activation.
Biochemistry, 9, 1970
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3I2E
 | | Crystal structure of human dimethylarginine dymethylaminohydrolase-1 (DDAH-1) | | Descriptor: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | | Authors: | Monzingo, A.F, Wang, Y, Hu, S, Schaller, T.H, Robertus, J.D, Fast, W. | | Deposit date: | 2009-06-29 | | Release date: | 2009-08-25 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
Biochemistry, 48, 2009
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1EE9
 | | CRYSTAL STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH NAD | | Descriptor: | 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Monzingo, A.F, Breksa, A, Ernst, S, Appling, D.R, Robertus, J.D. | | Deposit date: | 2000-01-31 | | Release date: | 2000-12-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae.
Protein Sci., 9, 2000
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1EDZ
 | | STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE | | Descriptor: | 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE | | Authors: | Monzingo, A.F, Breksa, A, Ernst, S, Appling, D.R, Robertus, J.D. | | Deposit date: | 2000-01-28 | | Release date: | 2000-12-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae.
Protein Sci., 9, 2000
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3I4A
 | | Crystal structure of dimethylarginine dimethylaminohydrolase-1 (DDAH-1) in complex with N5-(1-iminopropyl)-L-ornithine | | Descriptor: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N5-(1-iminopropyl)-L-ornithine | | Authors: | Monzingo, A.F, Wang, Y, Hu, S, Schaller, T.H, Fast, W, Robertus, J.D. | | Deposit date: | 2009-07-01 | | Release date: | 2009-08-25 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.898 Å) | | Cite: | Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
Biochemistry, 48, 2009
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3KWI
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3KWG
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2NS6
 | | Crystal Structure of the Minimal Relaxase Domain of MobA from Plasmid R1162 | | Descriptor: | MANGANESE (II) ION, Mobilization protein A | | Authors: | Monzingo, A.F, Ozburn, A, Xia, S, Meyer, R.J, Robertus, J.D. | | Deposit date: | 2006-11-03 | | Release date: | 2007-02-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Structure of the Minimal Relaxase Domain of MobA at 2.1 A Resolution.
J.Mol.Biol., 366, 2007
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2P9Q
 | | Crystal Structure of Phosphoglycerate Kinase-2 | | Descriptor: | Phosphoglycerate kinase, testis specific | | Authors: | Sawyer, G.M, Monzingo, A.F, Poteet, E.C, Robertus, J.D. | | Deposit date: | 2007-03-26 | | Release date: | 2007-11-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | X-ray analysis of phosphoglycerate kinase 2, a sperm-specific isoform from Mus musculus.
Proteins, 71, 2007
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2PAA
 | | Crystal structure of phosphoglycerate kinase-2 bound to atp and 3pg | | Descriptor: | 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Phosphoglycerate kinase, ... | | Authors: | Sawyer, G.M, Monzingo, A.F, Poteet, E.C, Robertus, J.D. | | Deposit date: | 2007-03-27 | | Release date: | 2007-11-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | X-ray analysis of phosphoglycerate kinase 2, a sperm-specific isoform from Mus musculus.
Proteins, 71, 2007
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