5VCA
| VCP like ATPase from T. acidophilum (VAT)-Substrate bound conformation | Descriptor: | VCP-like ATPase | Authors: | Ripstein, Z.A, Huang, R, Augustyniak, R, Kay, L.E, Rubinstein, J.L. | Deposit date: | 2017-03-31 | Release date: | 2017-04-26 | Last modified: | 2020-01-15 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure of a AAA+ unfoldase in the process of unfolding substrate. Elife, 6, 2017
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5VC7
| VCP like ATPase from T. acidophilum (VAT) - conformation 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, VCP-like ATPase | Authors: | Ripstein, Z.A, Huang, R, Augustyniak, R, Kay, L.E, Rubinstein, J.L. | Deposit date: | 2017-03-31 | Release date: | 2017-04-26 | Last modified: | 2020-01-15 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of a AAA+ unfoldase in the process of unfolding substrate. Elife, 6, 2017
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6VFX
| ClpXP from Neisseria meningitidis - Conformation B | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | Authors: | Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E. | Deposit date: | 2020-01-06 | Release date: | 2020-01-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery. Elife, 9, 2020
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6VFS
| ClpXP from Neisseria meningitidis - Conformation A | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | Authors: | Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E. | Deposit date: | 2020-01-06 | Release date: | 2020-01-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery. Elife, 9, 2020
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6DKF
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6VGQ
| ClpP1P2 complex from M. tuberculosis with GLF-CMK bound to ClpP1 | Descriptor: | ATP-dependent Clp protease proteolytic subunit, ATP-dependent Clp protease proteolytic subunit 1, Z-Gly-leu-phe-CH2Cl | Authors: | Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E. | Deposit date: | 2020-01-08 | Release date: | 2020-03-18 | Last modified: | 2020-04-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR. Proc.Natl.Acad.Sci.USA, 117, 2020
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6VGK
| ClpP1P2 complex from M. tuberculosis | Descriptor: | ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2 | Authors: | Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E. | Deposit date: | 2020-01-08 | Release date: | 2020-03-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR. Proc.Natl.Acad.Sci.USA, 117, 2020
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6VGN
| ClpP1P2 complex from M. tuberculosis bound to ADEP | Descriptor: | ATP-dependent Clp protease proteolytic subunit, ATP-dependent Clp protease proteolytic subunit 1, R0M-WFP-ALO-PRO-YCP-ALA-MP8 | Authors: | Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E. | Deposit date: | 2020-01-08 | Release date: | 2020-03-18 | Last modified: | 2020-04-01 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR. Proc.Natl.Acad.Sci.USA, 117, 2020
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5G4G
| Structure of the ATPgS-bound VAT complex | Descriptor: | VCP-LIKE ATPASE | Authors: | Huang, R, Ripstein, Z.A, Augustyniak, R, Lazniewski, M, Ginalski, K, Kay, L.E, Rubinstein, J.L. | Deposit date: | 2016-05-12 | Release date: | 2016-07-27 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Unfolding the Mechanism of the Aaa+ Unfoldase Vat by a Combined Cryo-Em, Solution NMR Study. Proc.Natl.Acad.Sci.USA, 113, 2016
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5G4F
| Structure of the ADP-bound VAT complex | Descriptor: | VCP-LIKE ATPASE | Authors: | Huang, R, Ripstein, Z.A, Augustyniak, R, Lazniewski, M, Ginalski, K, Kay, L.E, Rubinstein, J.L. | Deposit date: | 2016-05-12 | Release date: | 2016-07-27 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Unfolding the Mechanism of the Aaa+ Unfoldase Vat by a Combined Cryo-Em, Solution NMR Study. Proc.Natl.Acad.Sci.USA, 113, 2016
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8F1U
| Structure of a 24mer DegP cage bound to the client protein hTRF1 | Descriptor: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | Authors: | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | Deposit date: | 2022-11-06 | Release date: | 2022-11-23 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (13.8 Å) | Cite: | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP. J.Am.Chem.Soc., 145, 2023
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8F21
| Structure of a 30mer DegP cage bound to the client protein hTRF1 | Descriptor: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | Authors: | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | Deposit date: | 2022-11-06 | Release date: | 2022-11-23 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (14.1 Å) | Cite: | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP. J.Am.Chem.Soc., 145, 2023
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8F26
| Structure of a 60mer DegP cage bound to the client protein hTRF1 | Descriptor: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | Authors: | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | Deposit date: | 2022-11-07 | Release date: | 2022-11-23 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP. J.Am.Chem.Soc., 145, 2023
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8F0A
| Client-bound structure of a DegP trimer within a 12mer cage | Descriptor: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | Authors: | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | Deposit date: | 2022-11-02 | Release date: | 2022-11-23 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP. J.Am.Chem.Soc., 145, 2023
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8F0U
| Structure of a 12mer DegP cage bound to the client protein hTRF1 | Descriptor: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | Authors: | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | Deposit date: | 2022-11-04 | Release date: | 2022-11-23 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP. J.Am.Chem.Soc., 145, 2023
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8F1T
| Structure of an 18mer DegP cage bound to the client protein hTRF1 | Descriptor: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | Authors: | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | Deposit date: | 2022-11-06 | Release date: | 2022-11-23 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (12.1 Å) | Cite: | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP. J.Am.Chem.Soc., 145, 2023
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7KR2
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