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6HV2
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MMP-13 IN COMPLEX WITH THE PEPTIDE IMISF
Descriptor:Collagenase 3, ZINC ION, CALCIUM ION, ...
Authors:Mittl, P., Riedl, R., Hohl, D.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.709 Å)
Cite:Drug Design Inspired by Nature: Crystallographic Detection of an Auto-Tailored Protease Inhibitor Template.
Angew.Chem.Int.Ed.Engl., 58, 2019
4WV5
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HEAT SHOCK PROTEIN 70 SUBSTRATE BINDING DOMAIN
Descriptor:Heat shock 70 kDa protein 1A/1B, GLYCEROL
Authors:Kirby, C., Stams, T., Baird, J.
Deposit date:2014-11-04
Release date:2015-01-14
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:The novolactone natural product disrupts the allosteric regulation of hsp70.
Chem.Biol., 22, 2015
4WV7
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HEAT SHOCK PROTEIN 70 SUBSTRATE BINDING DOMAIN WITH COVALENTLY LINKED NOVOLACTONE
Descriptor:Heat shock 70 kDa protein 1A/1B, (5beta,6alpha,8alpha,14alpha)-13-ethenyl-5,6-dihydroxy-14-methylpodocarp-12-en-15-oic acid
Authors:Kirby, C.A., Baird, J., Stams, T.
Deposit date:2014-11-04
Release date:2015-01-14
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:The novolactone natural product disrupts the allosteric regulation of hsp70.
Chem.Biol., 22, 2015
4FN5
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ELONGATION FACTOR G 1 (PSEUDOMONAS AERUGINOSA) IN COMPLEX WITH ARGYRIN B
Descriptor:Elongation factor G 1, Argyrin B
Authors:Kirby, C.A., Palestrant, D.
Deposit date:2012-06-19
Release date:2012-09-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification of elongation factor g as the conserved cellular target of argyrin B.
Plos One, 7, 2012
2HD5
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USP2 IN COMPLEX WITH UBIQUITIN
Descriptor:Ubiquitin carboxyl-terminal hydrolase 2, Polyubiquitin, ZINC ION
Authors:Renatus, M., Kroemer, M.
Deposit date:2006-06-20
Release date:2006-08-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis of Ubiquitin Recognition by the Deubiquitinating Protease USP2.
Structure, 14, 2006
5HL7
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH LEFAMULIN
Descriptor:50S ribosomal protein L2, 23S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Rozenberg, H., Zimmerman, E., Bashan, A., Yonath, A.
Deposit date:2016-01-14
Release date:2016-12-21
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
Sci Rep, 6, 2016
6F0E
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STRUCTURE OF YEAST SEC14P WITH A PICOLINAMIDE COMPOUND
Descriptor:SEC14 cytosolic factor, ~{N}-(1,3-benzodioxol-5-ylmethyl)-5-bromanyl-3-fluoranyl-pyridine-2-carboxamide
Authors:Hong, Z., Johnen, P., Schaaf, G., Bono, F.
Deposit date:2017-11-20
Release date:2018-01-17
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Target Identification and Mechanism of Action of Picolinamide and Benzamide Chemotypes with Antifungal Properties.
Cell Chem Biol, 25, 2018