Author results

1GUL
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HUMAN GLUTATHIONE TRANSFERASE A4-4 COMPLEX WITH IODOBENZYL GLUTATHIONE
分子名称:GLUTATHIONE TRANSFERASE A4-4, S-(2-iodobenzyl) glutathione
著者Bruns, C.M., Hubatsch, I., Ridderstrom, M., Mannervik, B., Tainer, J.A.
登録日1998-06-10
公開日1999-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products
J.Mol.Biol., 288, 1999
1GUM
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HUMAN GLUTATHIONE TRANSFERASE A4-4 WITHOUT LIGANDS
分子名称:PROTEIN (GLUTATHIONE TRANSFERASE A4-4)
著者Bruns, C.M., Hubatsch, I., Ridderstrom, M., Mannervik, B., Tainer, J.A.
登録日1998-06-11
公開日1999-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products
J.Mol.Biol., 288, 1999
4BV5
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IDENTIFICATION OF SMALL MOLECULE INHIBITORS SELECTIVE FOR APO(A) KRINGLES KIV-7, KIV-10 AND KV.
分子名称:APOLIPOPROTEIN(A), 4-(aminomethyl)-N-(benzenesulfonyl)cyclohexanecarboxamide
著者Sandmark, J., Althage, M., Andersson, G.M.K., Antonsson, T., Blaho, S., Bodin, C., Bostrom, J., Chen, Y., Dahlen, A., Eriksson, P.O., Evertsson, E., Fex, T., Fjellstrom, O., Gustafsson, D., Hallberg, C., Hicks, R., Jarkvist, E., Johansson, C., Kalies, I., Kang, D., Svalstedt Karlsson, B., Kartberg, F., Legnehed, A., Lindqvist, A.M., Martinsson, S.A., Moberg, A., Petersson, A.U., Ridderstrom, M., Thelin, A., Tigerstrom, A., Vinblad, J., Xu, B., Knecht, W.
登録日2013-06-25
公開日2014-07-09
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Small Molecules Used to Decipher the Pathophysiological Roles of the Kringle Domains Kiv-7, - 10 and Kv of Apolipoprotein(A)
To be Published
4BV7
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IDENTIFICATION OF SMALL MOLECULE INHIBITORS SELECTIVE FOR APO(A) KRINGLES KIV-7, KIV-10 AND KV.
分子名称:APOLIPOPROTEIN(A), ACETATE ION, 3-(4-piperidyl)propanoic acid
著者Sandmark, J., Althage, M., Andersson, G.M.K., Antonsson, T., Blaho, S., Bodin, C., Bostrom, J., Chen, Y., Dahlen, A., Eriksson, P.O., Evertsson, E., Fex, T., Fjellstrom, O., Gustafsson, D., Hallberg, C., Hicks, R., Jarkvist, E., Johansson, C., Kalies, I., Kang, D., Svalstedt Karlsson, B., Kartberg, F., Legnehed, A., Lindqvist, A.M., Martinsson, S.A., Moberg, A., Petersson, A.U., Ridderstrom, M., Thelin, A., Tigerstrom, A., Vinblad, J., Xu, B., Knecht, W.
登録日2013-06-25
公開日2014-07-09
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Small Molecules Used to Decipher the Pathophysiological Roles of the Kringle Domains Kiv-7, - 10 and Kv of Apolipoprotein(A)
To be Published
4BVC
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IDENTIFICATION OF SMALL MOLECULE INHIBITORS SELECTIVE FOR APO(A) KRINGLES KIV-7, KIV-10 AND KV.
分子名称:APOLIPOPROTEIN(A), CHLORIDE ION, 3-(4-PIPERIDYL)-N-[2-(TRIFLUOROMETHOXY)PHENYL]SULFONYL-PROPANAMIDE, ...
著者Sandmark, J., Althage, M., Andersson, G.M.K., Antonsson, T., Blaho, S., Bodin, C., Bostrom, J., Chen, Y., Dahlen, A., Eriksson, P.O., Evertsson, E., Fex, T., Fjellstrom, O., Gustafsson, D., Hallberg, C., Hicks, R., Jarkvist, E., Johansson, C., Kalies, I., Kang, D., Svalstedt Karlsson, B., Kartberg, F., Legnehed, A., Lindqvist, A.M., Martinsson, S.A., Moberg, A., Petersson, A.U., Ridderstrom, M., Thelin, A., Tigerstrom, A., Vinblad, J., Xu, B., Knecht, W.
登録日2013-06-25
公開日2014-07-09
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Small Molecules Used to Decipher the Pathophysiological Roles of the Kringle Domains Kiv-7, - 10 and Kv of Apolipoprotein(A)
To be Published
4BVD
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IDENTIFICATION OF SMALL MOLECULE INHIBITORS SELECTIVE FOR APO(A) KRINGLES KIV-7, KIV-10 AND KV.
分子名称:APOLIPOPROTEIN(A), CHLORIDE ION, 5-chloro-2-fluoro-N-[1-(4-piperidyl)pyrazol-4-yl]benzenesulfonamide
著者Sandmark, J., Althage, M., Andersson, G.M.K., Antonsson, T., Blaho, S., Bodin, C., Bostrom, J., Chen, Y., Dahlen, A., Eriksson, P.O., Evertsson, E., Fex, T., Fjellstrom, O., Gustafsson, D., Hallberg, C., Hicks, R., Jarkvist, E., Johansson, C., Kalies, I., Kang, D., Svalstedt Karlsson, B., Kartberg, F., Legnehed, A., Lindqvist, A.M., Martinsson, S.A., Moberg, A., Petersson, A.U., Ridderstrom, M., Thelin, A., Tigerstrom, A., Vinblad, J., Xu, B., Knecht, W.
登録日2013-06-25
公開日2014-07-16
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Small Molecules Used to Decipher the Pathophysiological Roles of the Kringle Domains Kiv-7, - 10 and Kv of Apolipoprotein(A)
To be Published
4BVV
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IDENTIFICATION OF SMALL MOLECULE INHIBITORS SELECTIVE FOR APO(A) KRINGLES KIV-7, KIV-10 AND KV.
分子名称:APOLIPOPROTEIN(A), 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, SULFATE ION
著者Sandmark, J., Althage, M., Andersson, G.M.K., Antonsson, T., Blaho, S., Bodin, C., Bostrom, J., Chen, Y., Dahlen, A., Eriksson, P.O., Evertsson, E., Fex, T., Fjellstrom, O., Gustafsson, D., Hallberg, C., Hicks, R., Jarkvist, E., Johansson, C., Kalies, I., Kang, D., Svalstedt Karlsson, B., Kartberg, F., Legnehed, A., Lindqvist, A.M., Martinsson, S.A., Moberg, A., Petersson, A.U., Ridderstrom, M., Thelin, A., Tigerstrom, A., Vinblad, J., Xu, B., Knecht, W.
登録日2013-06-28
公開日2014-07-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Small Molecules Used to Decipher the Pathophysiological Roles of the Kringle Domains Kiv-7, - 10 and Kv of Apolipoprotein(A)
To be Published
4BVW
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IDENTIFICATION OF SMALL MOLECULE INHIBITORS SELECTIVE FOR APO(A) KRINGLES KIV-7, KIV-10 AND KV.
分子名称:APOLIPOPROTEIN(A), CHLORIDE ION, 1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid, ...
著者Sandmark, J., Althage, M., Andersson, G.M.K., Antonsson, T., Blaho, S., Bodin, C., Bostrom, J., Chen, Y., Dahlen, A., Eriksson, P.O., Evertsson, E., Fex, T., Fjellstrom, O., Gustafsson, D., Hallberg, C., Hicks, R., Jarkvist, E., Johansson, C., Kalies, I., Kang, D., Svalstedt Karlsson, B., Kartberg, F., Legnehed, A., Lindqvist, A.M., Martinsson, S.A., Moberg, A., Petersson, A.U., Ridderstrom, M., Thelin, A., Tigerstrom, A., Vinblad, J., Xu, B., Knecht, W.
登録日2013-06-28
公開日2014-07-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Small Molecules Used to Decipher the Pathophysiological Roles of the Kringle Domains Kiv-7, - 10 and Kv of Apolipoprotein(A)
To be Published
1QH3
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HUMAN GLYOXALASE II WITH CACODYLATE AND ACETATE IONS PRESENT IN THE ACTIVE SITE
分子名称:PROTEIN (HYDROXYACYLGLUTATHIONE HYDROLASE), ZINC ION, CACODYLATE ION, ...
著者Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
登録日1999-05-10
公開日1999-09-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
1QH5
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HUMAN GLYOXALASE II WITH S-(N-HYDROXY-N-BROMOPHENYLCARBAMOYL)GLUTATHIONE
分子名称:PROTEIN (HYDROXYACYLGLUTATHIONE HYDROLASE), ZINC ION, GLUTATHIONE, ...
著者Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
登録日1999-05-11
公開日1999-09-24
最終更新日2011-12-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
1QIN
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HUMAN GLYOXALASE I COMPLEXED WITH S-(N-HYDROXY-N-P-IODOPHENYLCARBAMOYL) GLUTATHIONE
分子名称:PROTEIN (LACTOYLGLUTATHIONE LYASE), ZINC ION, S-(N-HYDROXY-N-IODOPHENYLCARBAMOYL)GLUTATHIONE
著者Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
登録日1999-06-14
公開日1999-11-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38, 1999
1QIP
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HUMAN GLYOXALASE I COMPLEXED WITH S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE
分子名称:PROTEIN (LACTOYLGLUTATHIONE LYASE), ZINC ION, S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE, ...
著者Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
登録日1999-06-14
公開日1999-11-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38, 1999
1BH5
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HUMAN GLYOXALASE I Q33E, E172Q DOUBLE MUTANT
分子名称:LACTOYLGLUTATHIONE LYASE, ZINC ION, S-HEXYLGLUTATHIONE
著者Cameron, A.D., Jones, T.A.
登録日1998-06-13
公開日1998-11-04
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Involvement of an active-site Zn2+ ligand in the catalytic mechanism of human glyoxalase I.
J.Biol.Chem., 273, 1998
1FRO
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HUMAN GLYOXALASE I WITH BENZYL-GLUTATHIONE INHIBITOR
分子名称:LACTOYLGLUTATHIONE LYASE, ZINC ION, S-BENZYL-GLUTATHIONE
著者Cameron, A.D., Jones, T.A.
登録日1997-02-25
公開日1997-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping.
EMBO J., 16, 1997