Author results

1LBK
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CRYSTAL STRUCTURE OF A RECOMBINANT GLUTATHIONE TRANSFERASE, CREATED BY REPLACING THE LAST SEVEN RESIDUES OF EACH SUBUNIT OF THE HUMAN CLASS PI ISOENZYME WITH THE ADDITIONAL C-TERMINAL HELIX OF HUMAN CLASS ALPHA ISOENZYME
Descriptor:Glutathione S-transferase class pi chimaera (CODA), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, ...
Authors:Kong, G.K.W., Micaloni, C., Mazzetti, A.P., Nuccetelli, M., Antonini, G., Stella, L., McKinstry, W.J., Polekhina, G., Rossjohn, J., Federici, G., Ricci, G., Parker, M.W., Lo Bello, M.
Deposit date:2002-04-04
Release date:2002-04-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences.
J.Mol.Biol., 325, 2003
14GS
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GLUTATHIONE S-TRANSFERASE P1-1 APO FORM 1
Descriptor:GLUTATHIONE S-TRANSFERASE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Oakley, A.J., Lo Bello, M., Ricci, G., Federici, G., Parker, M.W.
Deposit date:1997-11-29
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Evidence for an induced-fit mechanism operating in pi class glutathione transferases.
Biochemistry, 37, 1998
16GS
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GLUTATHIONE S-TRANSFERASE P1-1 APO FORM 3
Descriptor:GLUTATHIONE S-TRANSFERASE, SULFATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Oakley, A.J., Lo Bello, M., Ricci, G., Federici, G., Parker, M.W.
Deposit date:1997-11-30
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evidence for an induced-fit mechanism operating in pi class glutathione transferases.
Biochemistry, 37, 1998
3FR3
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TETRAMERIZATION AND COOPERATIVITY IN PLASMODIUM FALCIPARUM GLUTATHIONE TRANSFERASE ARE MEDIATED BY THE ATYPIC LOOP 113-118
Descriptor:Glutathione S-transferase, OXIDIZED GLUTATHIONE DISULFIDE
Authors:Perbandt, M., Liebau, E., Ricci, G.
Deposit date:2009-01-08
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118
To be Published
3FR6
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TETRAMERIZATION AND COOPERATIVITY IN PLASMODIUM FALCIPARUM GLUTATHIONE TRANSFERASE ARE MEDIATED BY THE ATYPIC LOOP 113-118
Descriptor:Glutathione S-transferase, MAGNESIUM ION
Authors:Perbandt, M., Liebau, E., Ricci, G.
Deposit date:2009-01-08
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118
To be Published
3FR9
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TETRAMERIZATION AND COOPERATIVITY IN PLASMODIUM FALCIPARUM GLUTATHIONE TRANSFERASE ARE MEDIATED BY THE ATYPIC LOOP 113-118
Descriptor:Glutathione S-transferase, GLUTATHIONE, CHLORIDE ION
Authors:Perbandt, M., Liebau, E., Ricci, G.
Deposit date:2009-01-08
Release date:2010-01-26
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118
To be Published
3FRC
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TETRAMERIZATION AND COOPERATIVITY IN PLASMODIUM FALCIPARUM GLUTATHIONE TRANSFERASE ARE MEDIATED BY THE ATYPIC LOOP 113-118
Descriptor:Glutathione S-transferase, N-[(4S)-4-ammonio-4-carboxybutanoyl]-S-(4-bromobenzyl)-L-cysteinylglycine
Authors:Perbandt, M., Liebau, E., Ricci, G.
Deposit date:2009-01-08
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118
To be Published
4GSS
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HUMAN GLUTATHIONE S-TRANSFERASE P1-1 Y108F MUTANT
Descriptor:GLUTATHIONE S-TRANSFERASE, S-HEXYLGLUTATHIONE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Oakley, A., Rossjohn, J., Parker, M.
Deposit date:1997-01-20
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme.
Biochemistry, 36, 1997
18GS
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GLUTATHIONE S-TRANSFERASE P1-1 COMPLEXED WITH 1-(S-GLUTATHIONYL)-2,4-DINITROBENZENE
Descriptor:GLUTATHIONE S-TRANSFERASE, GLUTATHIONE S-(2,4 DINITROBENZENE), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Oakley, A.J., Lo Bello, M., Ricci, G., Federici, G., Parker, M.W.
Deposit date:1997-12-07
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site).
J.Mol.Biol., 291, 1999
1ZGN
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CRYSTAL STRUCTURE OF THE GLUTATHIONE TRANSFERASE PI IN COMPLEX WITH DINITROSYL-DIGLUTATHIONYL IRON COMPLEX
Descriptor:Glutathione S-transferase P, FE (III) ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Parker, L.J., Adams, J.J., Parker, M.W.
Deposit date:2005-04-21
Release date:2005-11-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo
J.Biol.Chem., 280, 2005
10GS
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HUMAN GLUTATHIONE S-TRANSFERASE P1-1, COMPLEX WITH TER117
Descriptor:GLUTATHIONE S-TRANSFERASE P1-1, L-gamma-glutamyl-S-benzyl-N-[(S)-carboxy(phenyl)methyl]-L-cysteinamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Oakley, A., Parker, M.
Deposit date:1997-08-14
Release date:1998-09-16
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution.
J.Mol.Biol., 274, 1997
5GSS
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HUMAN GLUTATHIONE S-TRANSFERASE P1-1, COMPLEX WITH GLUTATHIONE
Descriptor:GLUTATHIONE S-TRANSFERASE P1-1, GLUTATHIONE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Oakley, A., Parker, M.
Deposit date:1997-08-11
Release date:1998-09-16
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution.
J.Mol.Biol., 274, 1997
6GSS
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HUMAN GLUTATHIONE S-TRANSFERASE P1-1, COMPLEX WITH GLUTATHIONE
Descriptor:GLUTATHIONE S-TRANSFERASE P1-1, GLUTATHIONE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Oakley, A., Parker, M.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution.
J.Mol.Biol., 274, 1997
7GSS
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HUMAN GLUTATHIONE S-TRANSFERASE P1-1, COMPLEX WITH GLUTATHIONE
Descriptor:GLUTATHIONE S-TRANSFERASE P1-1, GLUTATHIONE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Oakley, A., Parker, M.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution.
J.Mol.Biol., 274, 1997
8GSS
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HUMAN GLUTATHIONE S-TRANSFERASE P1-1, COMPLEX WITH GLUTATHIONE
Descriptor:GLUTATHIONE S-TRANSFERASE P1-1, SULFATE ION, GLUTATHIONE, ...
Authors:Oakley, A., Parker, M.
Deposit date:1997-08-14
Release date:1998-09-16
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution.
J.Mol.Biol., 274, 1997
9GSS
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HUMAN GLUTATHIONE S-TRANSFERASE P1-1, COMPLEX WITH S-HEXYL GLUTATHIONE
Descriptor:GLUTATHIONE S-TRANSFERASE P1-1, SULFATE ION, S-HEXYLGLUTATHIONE, ...
Authors:Oakley, A., Parker, M.
Deposit date:1997-08-14
Release date:1998-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution.
J.Mol.Biol., 274, 1997
5DAK
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE PI COMPLEXED WITH A METALLOID IN THE ABSENCE OF GLUTATHIONE
Descriptor:Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ARSENIC
Authors:Parker, L.J., Parker, M.W., Morton, C.J.
Deposit date:2015-08-20
Release date:2016-12-07
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
5DAL
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE PI COMPLEXED WITH A METALLOID IN THE PRESENCE OF GLUTATHIONE
Descriptor:Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Di-glutathione-PhenylArsine, ...
Authors:Parker, L.J., Parker, M.W., Morton, C.J.
Deposit date:2015-08-20
Release date:2016-12-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
5DCG
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CRYSTAL STRUCTURE OF WT APO HUMAN GLUTATHIONE TRANSFERASE PI
Descriptor:Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHOSPHATE ION, ...
Authors:Parker, L.J., Parker, M.W., Morton, C.J.
Deposit date:2015-08-24
Release date:2016-12-07
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
5DDL
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CRYSTAL STRUCTURE OF WT HUMAN GLUTATHIONE TRANSFERASE PI SOAKED WITH A METALLOID THEN BACK-SOAKED WITH GLUTATHIONE
Descriptor:Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Di-glutathione-PhenylArsine, ...
Authors:Parker, L.J., Parker, M.W., Morton, C.J.
Deposit date:2015-08-25
Release date:2016-10-26
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
19GS
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GLUTATHIONE S-TRANSFERASE P1-1
Descriptor:GLUTATHIONE S-TRANSFERASE, 3,3'-(4,5,6,7-TETRABROMO-3-OXO-1(3H)-ISOBENZOFURANYLIDENE)BIS [6-HYDROXYBENZENESULFONIC ACID]ANION, GLUTATHIONE, ...
Authors:Oakley, A.J., Lo Bello, M., Parker, M.W.
Deposit date:1997-12-14
Release date:1998-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site).
J.Mol.Biol., 291, 1999
20GS
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GLUTATHIONE S-TRANSFERASE P1-1 COMPLEXED WITH CIBACRON BLUE
Descriptor:GLUTATHIONE S-TRANSFERASE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CIBACRON BLUE
Authors:Oakley, A.J., Lo Bello, M., Nuccetelli, M., Mazzetti, A.P., Parker, M.W.
Deposit date:1997-12-16
Release date:1998-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site).
J.Mol.Biol., 291, 1999
22GS
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HUMAN GLUTATHIONE S-TRANSFERASE P1-1 Y49F MUTANT
Descriptor:GLUTATHIONE S-TRANSFERASE P1-1, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Oakley, A.J.
Deposit date:1998-03-10
Release date:1999-03-23
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione.
J.Biol.Chem., 278, 2003