Author results

1XQH
  • Download 1xqh
  • View 1xqh
Molmil generated image of 1xqh
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE METHYLTRANSFERASE SET9 (ALSO KNOWN AS SET7/9) WITH A P53 PEPTIDE AND SAH
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-4 specific, 9-mer peptide from tumor protein p53, ...
Authors:Chuikov, S., Kurash, J.K., Wilson, J.R., Xiao, B., Justin, N., Ivanov, G.S., McKinney, K., Tempst, P., Prives, C., Gamblin, S.J., Barlev, N.A., Reinberg, D.
Deposit date:2004-10-12
Release date:2004-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Regulation of p53 activity through lysine methylation
Nature, 432, 2004
2BQZ
  • Download 2bqz
  • View 2bqz
Molmil generated image of 2bqz
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE METHYLTRANSFERASE PR-SET7 (ALSO KNOWN AS SET8)
Descriptor:SET8 PROTEIN, HISTONE H4, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Xiao, B., Jing, C., Kelly, G., Walker, P.A., Muskett, F.W., Frenkiel, T.A., Martin, S.R., Sarma, K., Reinberg, D., Gamblin, S.J., Wilson, J.R.
Deposit date:2005-04-28
Release date:2005-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Specificity and Mechanism of the Histone Methyltransferase Pr-Set7
Genes Dev., 19, 2005
1TFB
  • Download 1tfb
  • View 1tfb
Molmil generated image of 1tfb
NMR STUDIES OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB: DYNAMICS AND INTERACTION WITH VP16 ACTIVATION DOMAIN, 20 STRUCTURES
Descriptor:TFIIB
Authors:Bagby, S., Ikura, M.
Deposit date:1996-11-14
Release date:1997-03-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Human general transcription factor TFIIB: conformational variability and interaction with VP16 activation domain.
Biochemistry, 37, 1998
3IIW
  • Download 3iiw
  • View 3iiw
Molmil generated image of 3iiw
CRYSTAL STRUCTURE OF EED IN COMPLEX WITH A TRIMETHYLATED HISTONE H3K27 PEPTIDE
Descriptor:Polycomb protein EED, Histone H3 peptide
Authors:Justin, N., Sharpe, M.L., Martin, S., Taylor, W.R., De Marco, V., Gamblin, S.J.
Deposit date:2009-08-03
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
3IIY
  • Download 3iiy
  • View 3iiy
Molmil generated image of 3iiy
CRYSTAL STRUCTURE OF EED IN COMPLEX WITH A TRIMETHYLATED HISTONE H1K26 PEPTIDE
Descriptor:Polycomb protein EED, Histone H1K26 peptide
Authors:Justin, N., Sharpe, M.L., Martin, S., Taylor, W.R., De Marco, V., Gamblin, S.J.
Deposit date:2009-08-03
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
3IJ0
  • Download 3ij0
  • View 3ij0
Molmil generated image of 3ij0
CRYSTAL STRUCTURE OF EED IN COMPLEX WITH A TRIMETHYLATED HISTONE H3K9 PEPTIDE
Descriptor:Polycomb protein EED, Histone H3K9 peptide
Authors:Justin, N., Sharpe, M.L., Martin, S., Taylor, W.R., De Marco, V., Gamblin, S.J.
Deposit date:2009-08-03
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
3IJ1
  • Download 3ij1
  • View 3ij1
Molmil generated image of 3ij1
CRYSTAL STRUCTURE OF EED IN COMPLEX WITH A TRIMETHYLATED HISTONE H4K20 PEPTIDE
Descriptor:Polycomb protein EED, Histone H4K20 peptide
Authors:Justin, N., Sharpe, M.L., Martin, S., Taylor, W.R., De Marco, V., Gamblin, S.J.
Deposit date:2009-08-03
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
3IJC
  • Download 3ijc
  • View 3ijc
Molmil generated image of 3ijc
CRYSTAL STRUCTURE OF EED IN COMPLEX WITH NDSB-195
Descriptor:Polycomb protein EED, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE
Authors:Justin, N., Sharpe, M.L., Martin, S., Taylor, W.R., De Marco, V., Gamblin, S.J.
Deposit date:2009-08-04
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
3OOI
  • Download 3ooi
  • View 3ooi
Molmil generated image of 3ooi
CRYSTAL STRUCTURE OF HUMAN HISTONE-LYSINE N-METHYLTRANSFERASE NSD1 SET DOMAIN IN COMPLEX WITH S-ADENOSYL-L-METHIONINE
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, ZINC ION, ...
Authors:Qiao, Q., Wang, M., Xu, R.M.
Deposit date:2010-08-31
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation
J.Biol.Chem., 286, 2010
3PMT
  • Download 3pmt
  • View 3pmt
Molmil generated image of 3pmt
CRYSTAL STRUCTURE OF THE TUDOR DOMAIN OF HUMAN TUDOR DOMAIN-CONTAINING PROTEIN 3
Descriptor:Tudor domain-containing protein 3, TETRAETHYLENE GLYCOL
Authors:Lam, R., Bian, C.B., Guo, Y.H., Xu, C., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-11-18
Release date:2010-12-01
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30.
Plos One, 7, 2012
3Q0B
  • Download 3q0b
  • View 3q0b
Molmil generated image of 3q0b
CRYSTAL STRUCTURE OF SUVH5 SRA- FULLY METHYLATED CG DNA COMPLEX IN SPACE GROUP P42212
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5, DNA (5'-D(*AP*CP*TP*AP*(5CM)P*GP*TP*AP*GP*T)-3')
Authors:Eerappa, R., Simanshu, D.K., Patel, D.J.
Deposit date:2010-12-15
Release date:2011-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
3Q0C
  • Download 3q0c
  • View 3q0c
Molmil generated image of 3q0c
CRYSTAL STRUCTURE OF SUVH5 SRA-FULLY METHYLATED CG DNA COMPLEX IN SPACE GROUP P6122
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5, DNA (5'-D(*AP*CP*TP*AP*(5CM)P*GP*TP*AP*GP*TP*T)-3'), ...
Authors:Eerappa, R., Simanshu, D.K., Patel, D.J.
Deposit date:2010-12-15
Release date:2011-02-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6567 Å)
Cite:A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
3Q0D
  • Download 3q0d
  • View 3q0d
Molmil generated image of 3q0d
CRYSTAL STRUCTURE OF SUVH5 SRA- HEMI METHYLATED CG DNA COMPLEX
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5, DNA (5'-D(*TP*CP*CP*AP*(5CM)P*GP*TP*CP*AP*G)-3'), ...
Authors:Eerappa, R., Simanshu, D.K., Patel, D.J.
Deposit date:2010-12-15
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3704 Å)
Cite:A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
3Q0F
  • Download 3q0f
  • View 3q0f
Molmil generated image of 3q0f
CRYSTAL STRUCTURE OF SUVH5 SRA- METHYLATED CHH DNA COMPLEX
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5, DNA (5'-D(*CP*TP*GP*AP*GP*GP*AP*GP*TP*AP*T)-3'), ...
Authors:Eerappa, R., Simanshu, D.K., Patel, D.J.
Deposit date:2010-12-15
Release date:2011-02-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
3S6W
  • Download 3s6w
  • View 3s6w
Molmil generated image of 3s6w
CRYSTAL STRUCTURE OF TUDOR DOMAIN OF HUMAN TDRD3
Descriptor:Tudor domain-containing protein 3, ISOPROPYL ALCOHOL
Authors:Liu, H.P., Xu, R.M.
Deposit date:2011-05-26
Release date:2012-03-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30
Plos One, 7, 2012
4O30
  • Download 4o30
  • View 4o30
Molmil generated image of 4o30
CRYSTAL STRUCTURE OF ATXR5 IN COMPLEX WITH HISTONE H3.1 AND ADOHCY
Descriptor:Histone-lysine N-methyltransferase ATXR6, putative, histone H3.1, ...
Authors:Bergamin, E., Mongeon, V., Couture, J.F.
Deposit date:2013-12-17
Release date:2014-03-26
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication.
Science, 343, 2014
5HYN
  • Download 5hyn
  • View 5hyn
Molmil generated image of 5hyn
STRUCTURE OF HUMAN POLYCOMB REPRESSIVE COMPLEX 2 (PRC2) WITH ONCOGENIC HISTONE H3K27M PEPTIDE
Descriptor:Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, Polycomb protein SUZ12, ...
Authors:Zhang, Y., Justin, N., Wilson, J.R., Gamblin, S.J.
Deposit date:2016-02-01
Release date:2016-05-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Nat Commun, 7, 2016
1C9B
  • Download 1c9b
  • View 1c9b
Molmil generated image of 1c9b
CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
Descriptor:ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
Authors:Tsai, F.T.F., Sigler, P.B.
Deposit date:1999-08-01
Release date:2000-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
1D3U
  • Download 1d3u
  • View 1d3u
Molmil generated image of 1d3u
TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/BRE+TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI
Descriptor:DNA 24-MER: BRE+TATA-BOX, DNA 23-MER: BRE+TATA-BOX, TATA-BINDING PROTEIN, ...
Authors:Littlefield, O., Korkhin, Y., Sigler, P.B.
Deposit date:1999-10-01
Release date:1999-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structural basis for the oriented assembly of a TBP/TFB/promoter complex.
Proc.Natl.Acad.Sci.USA, 96, 1999