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6MHE
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GALPHAI3 CO-CRYSTALLIZED WITH KB752
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, KB752 peptide, GLYCEROL, ...
Authors:Rees, S.D., Kalogriopoulos, N.A., Ngo, T., Kopcho, N., Ilatovskiy, A., Sun, N., Komives, E., Chang, G., Ghosh, P., Kufareva, I.
Deposit date:2018-09-17
Release date:2019-07-31
Last modified:2019-08-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for GPCR-independent activation of heterotrimeric Gi proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
6MHF
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GALPHAI3 CO-CRYSTALLIZED WITH GIV/GIRDIN
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, Girdin, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Rees, S.D., Kalogriopoulos, N.A., Ngo, T., Kopcho, N., Ilatovskiy, A., Sun, N., Komives, E., Chang, G., Ghosh, P., Kufareva, I.
Deposit date:2018-09-17
Release date:2019-07-31
Last modified:2019-08-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for GPCR-independent activation of heterotrimeric Gi proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
6MNJ
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HADZA MICROBIAL SIALIDASE HZ136
Descriptor:Hz136
Authors:Rees, S.D., Zaramela, L., Zengler, K., Chang, G.
Deposit date:2018-10-01
Release date:2019-10-02
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 2019
4XWK
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P-GLYCOPROTEIN CO-CRYSTALLIZED WITH BDE-100
Descriptor:Multidrug resistance protein 1A, 2,4-dibromophenyl 2,4,6-tribromophenyl ether
Authors:McGrath, A.P., Rees, S.D., Chang, G.
Deposit date:2015-01-28
Release date:2016-04-27
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure.
Sci Adv, 2, 2016
6MRV
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SIALIDASE26 CO-CRYSTALLIZED WITH DANA
Descriptor:Sialidase26, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID
Authors:Zaramela, L.S., Martino, C., Alisson-Silva, F., Rees, S.D., Diaz, S.L., Chuzel, L., Ganatra, M.B., Taron, C.H., Zuniga, C., Chang, G., Varki, A., Zengler, K.
Deposit date:2018-10-15
Release date:2019-10-02
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 2019
6MRX
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SIALIDASE26 APO
Descriptor:Sialidase26
Authors:Zaramela, L.S., Martino, C., Alisson-Silva, F., Rees, S.D., Diaz, S.L., Chuzel, L., Ganatra, M.B., Taron, C.H., Zuniga, C., Chang, G., Varki, A., Zengler, K.
Deposit date:2018-10-15
Release date:2019-10-02
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 2019
6MYV
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SIALIDASE26 CO-CRYSTALLIZED WITH DANA-GC
Descriptor:Sialidase26, 2,6-anhydro-3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-L-altro-non-2-enonic acid
Authors:Zaramela, L.S., Martino, C., Alisson-Silva, F., Rees, S.D., Diaz, S.L., Chuzel, L., Ganatra, M.B., Taron, C.H., Zuniga, C., Huang, J., Siegel, D., Chang, G., Varki, A., Zengler, K.
Deposit date:2018-11-02
Release date:2019-10-02
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 2019
4Q9H
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P-GLYCOPROTEIN AT 3.4 A RESOLUTION
Descriptor:Multidrug resistance protein 1A
Authors:McGrath, A.P., Szewczyk, P., Chang, G.
Deposit date:2014-05-01
Release date:2015-03-04
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
4Q9I
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P-GLYCOPROTEIN COCRYSTALLISED WITH QZ-ALA
Descriptor:Multidrug resistance protein 1A, (30F)A(30F)A(30F)A Peptide
Authors:McGrath, A.P., Szewczyk, P., Chang, G.
Deposit date:2014-05-01
Release date:2015-03-04
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (3.781 Å)
Cite:Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
4Q9J
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P-GLYCOPROTEIN COCRYSTALLISED WITH QZ-VAL
Descriptor:Multidrug resistance protein 1A, N-{[5-AMINO-1-(5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-1H-IMIDAZOL-4-YL]CARBONYL}-L-ASPARTIC ACID
Authors:McGrath, A.P., Szewczyk, P., Chang, G.
Deposit date:2014-05-01
Release date:2015-03-04
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
4Q9K
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P-GLYCOPROTEIN COCRYSTALLISED WITH QZ-LEU
Descriptor:Multidrug resistance protein 1A, (30F)L(30F)L(30F)L Peptide
Authors:McGrath, A.P., Szewczyk, P., Chang, G.
Deposit date:2014-05-01
Release date:2015-03-04
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
4Q9L
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P-GLYCOPROTEIN COCRYSTALLISED WITH QZ-PHE
Descriptor:Multidrug resistance protein 1A, (30F)F(30F)F(30F)F Peptide
Authors:McGrath, A.P., Szewczyk, P., Chang, G.
Deposit date:2014-05-01
Release date:2015-03-04
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
6OCE
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STRUCTURE OF THE RICE HYPEROSMOLALITY-GATED ION CHANNEL OSCA1.2
Descriptor:stress-gated cation channel 1.2
Authors:Maity, K., Heumann, J.M., McGrath, A.P., Chang, G., Stowell, M.H.
Deposit date:2019-03-23
Release date:2019-07-03
Last modified:2019-07-24
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Cryo-EM structure of OSCA1.2 fromOryza sativaelucidates the mechanical basis of potential membrane hyperosmolality gating.
Proc.Natl.Acad.Sci.USA, 116, 2019