Author results

3IOL
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CRYSTAL STRUCTURE OF GLUCAGON-LIKE PEPTIDE-1 IN COMPLEX WITH THE EXTRACELLULAR DOMAIN OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR
Descriptor:Glucagon-like peptide 1 receptor, Glucagon, decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside
Authors:Reedtz-Runge, S.
Deposit date:2009-08-14
Release date:2009-10-27
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor
J.Biol.Chem., 285, 2010
4ZGM
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CRYSTAL STRUCTURE OF SEMAGLUTIDE PEPTIDE BACKBONE IN COMPLEX WITH THE GLP-1 RECEPTOR EXTRACELLULAR DOMAIN
Descriptor:Glucagon-like peptide 1 receptor, Semaglutide peptide backbone; 8Aib,34R-GLP-1(7-37)-OH, 3,6,9,12,15,18-hexaoxahexacosan-1-ol
Authors:Reedtz-Runge, S.
Deposit date:2015-04-23
Release date:2015-09-09
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide.
J.Med.Chem., 58, 2015
5E94
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ANTIBODY-BOUND GLUCAGON-LIKE PEPTIDE-1 RECEPTOR EXTRACELLULAR DOMAIN
Descriptor:Antibody Fab fragment light chain, Antibody Fab fragment heavy chain, Glucagon-like peptide 1 receptor
Authors:Soroka, V., Schluckebier, G., Reedtz-Runge, S.
Deposit date:2015-10-14
Release date:2016-08-24
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.
Sci Rep, 6, 2016
5II0
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CRYSTAL STRUCTURE OF THE HUMAN CALCITONIN RECEPTOR ECTODOMAIN IN COMPLEX WITH A TRUNCATED SALMON CALCITONIN ANALOGUE
Descriptor:Calcitonin receptor, Calcitonin, SODIUM ION, ...
Authors:Johansson, E., Reedtz-Runge, S.
Deposit date:2016-03-01
Release date:2016-05-11
Last modified:2016-07-06
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Type II Turn of Receptor-bound Salmon Calcitonin Revealed by X-ray Crystallography.
J.Biol.Chem., 291, 2016
5XEZ
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STRUCTURE OF THE FULL-LENGTH GLUCAGON CLASS B G PROTEIN-COUPLED RECEPTOR
Descriptor:Glucagon receptor,Endolysin,Glucagon receptor, Antibody, mAb1, ...
Authors:Zhang, H., Qiao, A., Yang, D., Yang, L., Dai, A., de Graaf, C., Reedtz-Runge, S., Dharmarajan, V., Zhang, H., Han, G.W., Grant, T., Sierra, R., Weierstall, U., Nelson, G., Liu, W., Wu, Y., Ma, L., Cai, X., Lin, G., Wu, X., Geng, Z., Dong, Y., Song, G., Griffin, P., Lau, J., Cherezov, V., Yang, H., Hanson, M., Stevens, R., Jiang, H., Wang, M., Zhao, Q., Wu, B.
Deposit date:2017-04-06
Release date:2017-05-24
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
5XF1
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STRUCTURE OF THE FULL-LENGTH GLUCAGON CLASS B G PROTEIN-COUPLED RECEPTOR
Descriptor:Glucagon receptor,Endolysin,Glucagon receptor, Antibody mAb1 Heavy chain, Antibody mAb1 Light chain, ...
Authors:Zhang, H., Qiao, A., Yang, D., Yang, L., Dai, A., de Graaf, C., Reedtz-Runge, S., Dharmarajan, V., Zhang, H., Han, G.W., Grant, T., Sierra, R., Weierstall, U., Nelson, G., Liu, W., Wu, Y., Ma, L., Cai, X., Lin, G., Wu, X., Geng, Z., Dong, Y., Song, G., Griffin, P., Lau, J., Cherezov, V., Yang, H., Hanson, M., Stevens, R., Jiang, H., Wang, M., Zhao, Q., Wu, B.
Deposit date:2017-04-06
Release date:2017-05-24
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
5OTT
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EXTRACELLULAR DOMAIN OF GLP-1 RECEPTOR IN COMPLEX WITH EXENDIN-4 VARIANT GLY2HCS/THR5HCS
Descriptor:Glucagon-like peptide 1 receptor, Exendin-4
Authors:Mortensen, S.
Deposit date:2017-08-22
Release date:2018-07-04
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4.
Biochemistry, 57, 2018
5OTU
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EXTRACELLULAR DOMAIN OF GLP-1 RECEPTOR IN COMPLEX WITH GLP-1 VARIANT ALA8HCS/THR11HCS
Descriptor:Glucagon-like peptide 1 receptor, Glucagon
Authors:Mortensen, S.
Deposit date:2017-08-22
Release date:2018-07-04
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4.
Biochemistry, 57, 2018
5OTV
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EXTRACELLULAR DOMAIN OF GLP-1 RECEPTOR IN COMPLEX WITH GLP-1 VARIANT ALA8CYC/THR11HCS
Descriptor:Glucagon-like peptide 1 receptor, Glucagon
Authors:Mortensen, S.
Deposit date:2017-08-22
Release date:2018-07-04
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4.
Biochemistry, 57, 2018
5OTW
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EXTRACELLULAR DOMAIN OF GLP-1 RECEPTOR IN COMPLEX WITH GLP-1 VARIANT ALA8HCS/THR11CYS
Descriptor:Glucagon-like peptide 1 receptor, Glucagon
Authors:Mortensen, S.
Deposit date:2017-08-22
Release date:2018-07-04
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4.
Biochemistry, 57, 2018
5OTX
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EXTRACELLULAR DOMAIN OF GLP-1 RECEPTOR IN COMPLEX WITH GLP-1 VARIANT ALA8CYS/THR11CYS
Descriptor:Glucagon-like peptide 1 receptor, Glucagon
Authors:Mortensen, S.
Deposit date:2017-08-22
Release date:2018-07-04
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4.
Biochemistry, 57, 2018
5YQZ
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STRUCTURE OF THE GLUCAGON RECEPTOR IN COMPLEX WITH A GLUCAGON ANALOGUE
Descriptor:Glucagon receptor,Endolysin,Glucagon receptor, Glucagon analogue, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhang, H., Qiao, A., Yang, L., VAN EPS, N., Frederiksen, K., Yang, D., Dai, A., Cai, X., Zhang, H., Yi, C., Can, C., He, L., Yang, H., Lau, J., Ernst, O., Hanson, M., Stevens, R., Wang, M., Seedtz-Runge, S., Jiang, H., Zhao, Q., Wu, B.
Deposit date:2017-11-08
Release date:2018-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the glucagon receptor in complex with a glucagon analogue.
Nature, 553, 2018