Author results

1FLK
  • Download 1flk
  • View 1flk
Molmil generated image of 1flk
MOLECULAR BASIS FOR CD40 SIGNALING MEDIATED BY TRAF3
分子名称:TNF RECEPTOR ASSOCIATED FACTOR 3
著者Ni, C.-Z., Welsh, K., Leo, E., Chiou, C.-K., Wu, H., Reed, J.C., Ely, K.R.
登録日2000-08-14
公開日2000-10-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis for CD40 signaling mediated by TRAF3.
Proc.Natl.Acad.Sci.USA, 97, 2000
1FLL
  • Download 1fll
  • View 1fll
Molmil generated image of 1fll
MOLECULAR BASIS FOR CD40 SIGNALING MEDIATED BY TRAF3
分子名称:TNF RECEPTOR ASSOCIATED FACTOR 3, B-CELL SURFACE ANTIGEN CD40
著者Ni, C.-Z., Welsh, K., Leo, E., Chiou, C.-K., Wu, H., Reed, J.C., Ely, K.R.
登録日2000-08-14
公開日2000-10-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular basis for CD40 signaling mediated by TRAF3.
Proc.Natl.Acad.Sci.USA, 97, 2000
1I6Z
  • Download 1i6z
  • View 1i6z
Molmil generated image of 1i6z
BAG DOMAIN OF BAG1 COCHAPERONE
分子名称:BAG-FAMILY MOLECULAR CHAPERONE REGULATOR-1
著者Briknarova, K., Takayama, S., Brive, L., Havert, M.L., Knee, D.A., Velasco, J., Homma, S., Cabezas, E., Stuart, J., Hoyt, D.W., Satterthwait, A.C., Llinas, M., Reed, J.C., Ely, K.R.
登録日2001-03-06
公開日2001-09-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein.
Nat.Struct.Biol., 8, 2001
1KZZ
  • Download 1kzz
  • View 1kzz
Molmil generated image of 1kzz
DOWNSTREAM REGULATOR TANK BINDS TO THE CD40 RECOGNITION SITE ON TRAF3
分子名称:TNF receptor associated factor 3, TRAF family member-associated NF-kappa-b activator
著者Li, C., Ni, C.-Z., Havert, M.L., Cabezas, E., He, J., Kaiser, D., Reed, J.C., Satterthwait, A.C., Cheng, G., Ely, K.R.
登録日2002-02-08
公開日2002-04-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Structure, 10, 2002
1L0A
  • Download 1l0a
  • View 1l0a
Molmil generated image of 1l0a
DOWNSTREAM REGULATOR TANK BINDS TO THE CD40 RECOGNITION SITE ON TRAF3
分子名称:TNF receptor associated factor 3, TRAF family member-associated NF-kappa-b activator
著者Li, C., Ni, C.-Z., Havert, M.L., Cabezas, E., He, J., Kaiser, D., Reed, J.C., Satterthwait, A.C., Cheng, G., Ely, K.R.
登録日2002-02-08
公開日2002-04-10
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Structure, 10, 2002
1OTV
  • Download 1otv
  • View 1otv
Molmil generated image of 1otv
PQQC, PYRROLOQUINOLINQUINONE SYNTHASE C
分子名称:Coenzyme PQQ synthesis protein C
著者Magnusson, O.T., Toyama, H., Saeki, M., Rojas, A., Reed, J.C., Adachi, O., Klinman, J.P., SChwarzenbacher, R.
登録日2003-03-23
公開日2004-05-11
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Quinone Biogenesis: Structure and Mechanism of PqqC, the Final Catalyst in the Production of Pyrroloquinoline Quinone.
Proc.Natl.Acad.Sci.USA, 101, 2004
1OTW
  • Download 1otw
  • View 1otw
Molmil generated image of 1otw
CRYSTAL STRUCTURE OF PQQC IN COMPLEX WITH PQQ AND A PUTATIVE H2O2
分子名称:Coenzyme PQQ synthesis protein C, PYRROLOQUINOLINE QUINONE, HYDROGEN PEROXIDE
著者Magnusson, O.T., Toyama, H., Saeki, M., Rojas, A., Reed, J.C., Liddington, R.C., Klinman, J.P., Schwarzenbacher, R.
登録日2003-03-23
公開日2004-05-11
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone.
Proc.Natl.Acad.Sci.USA, 101, 2004
1RF3
  • Download 1rf3
  • View 1rf3
Molmil generated image of 1rf3
STRUCTURALLY DISTINCT RECOGNITION MOTIFS IN LYMPHOTOXIN-B RECEPTOR AND CD40 FOR TRAF-MEDIATED SIGNALING
分子名称:TNF receptor associated factor 3, 24-residue peptide from Lymphotoxin-B Receptor
著者Li, C., Norris, P.S., Ni, C.Z., Havert, M.L., Chiong, E.M., Tran, B.R., Cabezas, E., Cheng, G., Reed, J.C., Satterthwait, A.C., Ware, C.F., Ely, K.R.
登録日2003-11-07
公開日2004-07-06
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling.
J.Biol.Chem., 278, 2003
1YSG
  • Download 1ysg
  • View 1ysg
Molmil generated image of 1ysg
SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-XL IN COMPLEX WITH "SAR BY NMR" LIGANDS
分子名称:Apoptosis regulator Bcl-X, 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID, 5,6,7,8-TETRAHYDRONAPHTHALEN-1-OL
著者Oltersdorf, T., Elmore, S.W., Shoemaker, A.R., Armstrong, R.C., Augeri, D.J., Belli, B.A., Bruncko, M., Deckwerth, T.L., Dinges, J., Hajduk, P.J., Joseph, M.K., Kitada, S., Korsmeyer, S.J., Kunzer, A.R., Letai, A., Li, C., Mitten, M.J., Nettesheim, D.G., Ng, S., Nimmer, P.M., O'Connor, J.M., Oleksijew, A., Petros, A.M., Reed, J.C., Shen, W., Tahir, S.K., Thompson, C.B., Tomaselli, K.J., Wang, B., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H.
登録日2005-02-08
公開日2005-06-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YSI
  • Download 1ysi
  • View 1ysi
Molmil generated image of 1ysi
SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-XL IN COMPLEX WITH AN ACYL-SULFONAMIDE-BASED LIGAND
分子名称:Apoptosis regulator Bcl-X, N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITRO-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE
著者Oltersdorf, T., Elmore, S.W., Shoemaker, A.R., Armstrong, R.C., Augeri, D.J., Belli, B.A., Bruncko, M., Deckwerth, T.L., Dinges, J., Hajduk, P.J., Joseph, M.K., Kitada, S., Korsmeyer, S.J., Kunzer, A.R., Letai, A., Li, C., Mitten, M.J., Nettesheim, D.G., Ng, S., Nimmer, P.M., O'Connor, J.M., Oleksijew, A., Petros, A.M., Reed, J.C., Shen, W., Tahir, S.K., Thompson, C.B., Tomaselli, K.J., Wang, B., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H.
登録日2005-02-08
公開日2005-06-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YSN
  • Download 1ysn
  • View 1ysn
Molmil generated image of 1ysn
SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-XL COMPLEXED WITH AN ACYL-SULFONAMIDE-BASED LIGAND
分子名称:Apoptosis regulator Bcl-X, 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE
著者Oltersdorf, T., Elmore, S.W., Shoemaker, A.R., Armstrong, R.C., Augeri, D.J., Belli, B.A., Bruncko, M., Deckwerth, T.L., Dinges, J., Hajduk, P.J., Joseph, M.K., Kitada, S., Korsmeyer, S.J., Kunzer, A.R., Letai, A., Li, C., Mitten, M.J., Nettesheim, D.G., Ng, S., Nimmer, P.M., O'Connor, J.M., Oleksijew, A., Petros, A.M., Reed, J.C., Shen, W., Tahir, S.K., Thompson, C.B., Tomaselli, K.J., Wang, B., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H.
登録日2005-02-08
公開日2005-06-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YSW
  • Download 1ysw
  • View 1ysw
Molmil generated image of 1ysw
SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-2 COMPLEXED WITH AN ACYL-SULFONAMIDE-BASED LIGAND
分子名称:Apoptosis regulator Bcl-2, 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE
著者Oltersdorf, T., Elmore, S.W., Shoemaker, A.R., Armstrong, R.C., Augeri, D.J., Belli, B.A., Bruncko, M., Deckwerth, T.L., Dinges, J., Hajduk, P.J., Joseph, M.K., Kitada, S., Korsmeyer, S.J., Kunzer, A.R., Letai, A., Li, C., Mitten, M.J., Nettesheim, D.G., Ng, S., Nimmer, P.M., O'Connor, J.M., Oleksijew, A., Petros, A.M., Reed, J.C., Shen, W., Tahir, S.K., Thompson, C.B., Tomaselli, K.J., Wang, B., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H.
登録日2005-02-09
公開日2005-06-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YSX
  • Download 1ysx
  • View 1ysx
Molmil generated image of 1ysx
SOLUTION STRUCTURE OF DOMAIN 3 FROM HUMAN SERUM ALBUMIN COMPLEXED TO AN ANTI-APOPTOTIC LIGAND DIRECTED AGAINST BCL-XL AND BCL-2
分子名称:Serum albumin, 4-({2-[(2,4-DIMETHYLPHENYL)SULFANYL]ETHYL}AMINO)-N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITROBENZENESULFONAMIDE
著者Oltersdorf, T., Elmore, S.W., Shoemaker, A.R., Armstrong, R.C., Augeri, D.J., Belli, B.A., Bruncko, M., Deckwerth, T.L., Dinges, J., Hajduk, P.J., Joseph, M.K., Kitada, S., Korsmeyer, S.J., Kunzer, A.R., Letai, A., Li, C., Mitten, M.J., Nettesheim, D.G., Ng, S., Nimmer, P.M., O'Connor, J.M., Oleksijew, A., Petros, A.M., Reed, J.C., Shen, W., Tahir, S.K., Thompson, C.B., Tomaselli, K.J., Wang, B., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H.
登録日2005-02-09
公開日2005-06-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1ZMS
  • Download 1zms
  • View 1zms
Molmil generated image of 1zms
LMP1 PROTEIN BINDS TO TRAF3 AS A STRUCTURAL CD40
分子名称:TNF receptor associated factor 3, Latent membrane protein 1
著者Wu, S.D., Xie, P., Welsh, K., Li, C., Ni, C.-Z., Zhu, X., Reed, J.C., Satterthwait, A.C., Bishop, G.A., Ely, K.R.
登録日2005-05-10
公開日2005-07-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献LMP1 protein from the Epstein Barr virus is a structural CD40 decoy in B lymphocytes fro binding to TRAF3
J.Biol.Chem., 39, 2005
2A25
  • Download 2a25
  • View 2a25
Molmil generated image of 2a25
CRYSTAL STRUCTURE OF SIAH1 SBD BOUND TO THE PEPTIDE EKPAAVVAPITTG FROM SIP
分子名称:Ubiquitin ligase SIAH1, Calcyclin-binding protein peptide, ZINC ION
著者Santelli, E., Leone, M., Li, C., Fukushima, T., Preece, N.E., Olson, A.J., Ely, K.R., Reed, J.C., Pellecchia, M., Liddington, R.C., Matsuzawa, S.
登録日2005-06-21
公開日2005-08-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex
J.Biol.Chem., 280, 2005
2A26
  • Download 2a26
  • View 2a26
Molmil generated image of 2a26
CRYSTAL STRUCTURE OF THE N-TERMINAL, DIMERIZATION DOMAIN OF SIAH INTERACTING PROTEIN
分子名称:Calcyclin-binding protein, SULFATE ION, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID
著者Santelli, E., Leone, M., Li, C., Fukushima, T., Preece, N.E., Olson, A.J., Ely, K.R., Reed, J.C., Pellecchia, M., Liddington, R.C., Matsuzawa, S.
登録日2005-06-21
公開日2005-08-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex
J.Biol.Chem., 280, 2005
1RCW
  • Download 1rcw
  • View 1rcw
Molmil generated image of 1rcw
CRYSTAL STRUCTURE OF CT610 FROM CHLAMYDIA TRACHOMATIS
分子名称:CT610, FE (III) ION
著者Schwarzenbacher, R., Liddington, R.C.
登録日2003-11-04
公開日2004-05-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Chlamydia protein CADD reveals a redox enzyme that modulates host cell apoptosis.
J.Biol.Chem., 279, 2004
2GKW
  • Download 2gkw
  • View 2gkw
Molmil generated image of 2gkw
KEY CONTACTS PROMOTE RECONGNITO OF BAFF-R BY TRAF3
分子名称:TNF receptor-associated factor 3, Tumor necrosis factor receptor superfamily member 13C
著者Ely, K.R.
登録日2006-04-03
公開日2006-04-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation.
J.Immunol., 173, 2004
2I39
  • Download 2i39
  • View 2i39
Molmil generated image of 2i39
CRYSTAL STRUCTURE OF VACCINIA VIRUS N1L PROTEIN
分子名称:Protein N1, (4S)-2-METHYL-2,4-PENTANEDIOL
著者Aoyagi, M., Aleshin, A.E., Stec, B., Liddington, R.C.
登録日2006-08-17
公開日2006-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein.
Protein Sci., 16, 2007
3H16
  • Download 3h16
  • View 3h16
Molmil generated image of 3h16
CRYSTAL STRUCTURE OF A BACTERIA TIR DOMAIN, PDTIR FROM PARACOCCUS DENITRIFICANS
分子名称:TIR protein, SULFATE ION
著者Chan, S.L., Low, L.Y., Santelli, E., Pascual, J.
登録日2009-04-11
公開日2009-06-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Mimicry in Innate Immunity: CRYSTAL STRUCTURE OF A BACTERIAL TIR DOMAIN.
J.Biol.Chem., 284, 2009
4EWI
  • Download 4ewi
  • View 4ewi
Molmil generated image of 4ewi
CRYSTAL STRUCTURE OF THE NLRP4 PYRIN DOMAIN
分子名称:NACHT, LRR and PYD domains-containing protein 4, CHLORIDE ION, ...
著者Eibl, C., Hessenberger, M., Puehringer, S., Page, R., Diederichs, K., Peti, W.
登録日2012-04-27
公開日2012-09-05
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural and Functional Analysis of the NLRP4 Pyrin Domain.
Biochemistry, 51, 2012