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1YSW
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BU of 1ysw by Molmil
Solution structure of the anti-apoptotic protein Bcl-2 complexed with an acyl-sulfonamide-based ligand
Descriptor: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-2
Authors:Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
Deposit date:2005-02-09
Release date:2005-06-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1I6Z
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BU of 1i6z by Molmil
BAG DOMAIN OF BAG1 COCHAPERONE
Descriptor: BAG-FAMILY MOLECULAR CHAPERONE REGULATOR-1
Authors:Briknarova, K, Takayama, S, Brive, L, Havert, M.L, Knee, D.A, Velasco, J, Homma, S, Cabezas, E, Stuart, J, Hoyt, D.W, Satterthwait, A.C, Llinas, M, Reed, J.C, Ely, K.R.
Deposit date:2001-03-06
Release date:2001-09-06
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein.
Nat.Struct.Biol., 8, 2001
1KZZ
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BU of 1kzz by Molmil
DOWNSTREAM REGULATOR TANK BINDS TO THE CD40 RECOGNITION SITE ON TRAF3
Descriptor: TNF receptor associated factor 3, TRAF family member-associated NF-kappa-b activator
Authors:Li, C, Ni, C.-Z, Havert, M.L, Cabezas, E, He, J, Kaiser, D, Reed, J.C, Satterthwait, A.C, Cheng, G, Ely, K.R.
Deposit date:2002-02-08
Release date:2002-04-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Structure, 10, 2002
1L0A
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BU of 1l0a by Molmil
DOWNSTREAM REGULATOR TANK BINDS TO THE CD40 RECOGNITION SITE ON TRAF3
Descriptor: TNF receptor associated factor 3, TRAF family member-associated NF-kappa-b activator
Authors:Li, C, Ni, C.-Z, Havert, M.L, Cabezas, E, He, J, Kaiser, D, Reed, J.C, Satterthwait, A.C, Cheng, G, Ely, K.R.
Deposit date:2002-02-08
Release date:2002-04-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Structure, 10, 2002
1YSG
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BU of 1ysg by Molmil
Solution Structure of the Anti-apoptotic Protein Bcl-xL in Complex with "SAR by NMR" Ligands
Descriptor: 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID, 5,6,7,8-TETRAHYDRONAPHTHALEN-1-OL, Apoptosis regulator Bcl-X
Authors:Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
Deposit date:2005-02-08
Release date:2005-06-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YSI
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BU of 1ysi by Molmil
Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand
Descriptor: Apoptosis regulator Bcl-X, N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITRO-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE
Authors:Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
Deposit date:2005-02-08
Release date:2005-06-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YSX
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Solution structure of domain 3 from human serum albumin complexed to an anti-apoptotic ligand directed against Bcl-xL and Bcl-2
Descriptor: 4-({2-[(2,4-DIMETHYLPHENYL)SULFANYL]ETHYL}AMINO)-N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITROBENZENESULFONAMIDE, Serum albumin
Authors:Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
Deposit date:2005-02-09
Release date:2005-06-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YSN
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BU of 1ysn by Molmil
Solution structure of the anti-apoptotic protein Bcl-xL complexed with an acyl-sulfonamide-based ligand
Descriptor: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-X
Authors:Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
Deposit date:2005-02-08
Release date:2005-06-07
Last modified:2023-11-29
Method:SOLUTION NMR
Cite:An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1ZMS
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BU of 1zms by Molmil
LMP1 Protein binds to TRAF3 as a structural CD40
Descriptor: Latent membrane protein 1, TNF receptor associated factor 3
Authors:Wu, S.D, Xie, P, Welsh, K, Li, C, Ni, C.-Z, Zhu, X, Reed, J.C, Satterthwait, A.C, Bishop, G.A, Ely, K.R.
Deposit date:2005-05-10
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:LMP1 protein from the Epstein Barr virus is a structural CD40 decoy in B lymphocytes fro binding to TRAF3
J.Biol.Chem., 39, 2005
2A25
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BU of 2a25 by Molmil
Crystal structure of Siah1 SBD bound to the peptide EKPAAVVAPITTG from SIP
Descriptor: Calcyclin-binding protein peptide, Ubiquitin ligase SIAH1, ZINC ION
Authors:Santelli, E, Leone, M, Li, C, Fukushima, T, Preece, N.E, Olson, A.J, Ely, K.R, Reed, J.C, Pellecchia, M, Liddington, R.C, Matsuzawa, S.
Deposit date:2005-06-21
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex
J.Biol.Chem., 280, 2005
2A26
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BU of 2a26 by Molmil
Crystal structure of the N-terminal, dimerization domain of Siah Interacting Protein
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Calcyclin-binding protein, SULFATE ION
Authors:Santelli, E, Leone, M, Li, C, Fukushima, T, Preece, N.E, Olson, A.J, Ely, K.R, Reed, J.C, Pellecchia, M, Liddington, R.C, Matsuzawa, S.
Deposit date:2005-06-21
Release date:2005-08-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex
J.Biol.Chem., 280, 2005
1OTW
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BU of 1otw by Molmil
Crystal structure of PqqC in complex with PQQ and a putative H2O2
Descriptor: Coenzyme PQQ synthesis protein C, HYDROGEN PEROXIDE, PYRROLOQUINOLINE QUINONE
Authors:Magnusson, O.T, Toyama, H, Saeki, M, Rojas, A, Reed, J.C, Liddington, R.C, Klinman, J.P, Schwarzenbacher, R.
Deposit date:2003-03-23
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone.
Proc.Natl.Acad.Sci.USA, 101, 2004
1OTV
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BU of 1otv by Molmil
PqqC, Pyrroloquinolinquinone Synthase C
Descriptor: Coenzyme PQQ synthesis protein C
Authors:Magnusson, O.T, Toyama, H, Saeki, M, Rojas, A, Reed, J.C, Adachi, O, Klinman, J.P, SChwarzenbacher, R.
Deposit date:2003-03-23
Release date:2004-05-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Quinone Biogenesis: Structure and Mechanism of PqqC, the Final Catalyst in the Production of Pyrroloquinoline Quinone.
Proc.Natl.Acad.Sci.USA, 101, 2004
1RF3
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BU of 1rf3 by Molmil
Structurally Distinct Recognition Motifs in Lymphotoxin-B Receptor and CD40 for TRAF-mediated Signaling
Descriptor: 24-residue peptide from Lymphotoxin-B Receptor, TNF receptor associated factor 3
Authors:Li, C, Norris, P.S, Ni, C.Z, Havert, M.L, Chiong, E.M, Tran, B.R, Cabezas, E, Cheng, G, Reed, J.C, Satterthwait, A.C, Ware, C.F, Ely, K.R.
Deposit date:2003-11-07
Release date:2004-07-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling.
J.Biol.Chem., 278, 2003
1FLL
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BU of 1fll by Molmil
MOLECULAR BASIS FOR CD40 SIGNALING MEDIATED BY TRAF3
Descriptor: B-CELL SURFACE ANTIGEN CD40, TNF RECEPTOR ASSOCIATED FACTOR 3
Authors:Ni, C.-Z, Welsh, K, Leo, E, Chiou, C.-K, Wu, H, Reed, J.C, Ely, K.R.
Deposit date:2000-08-14
Release date:2000-10-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular basis for CD40 signaling mediated by TRAF3.
Proc.Natl.Acad.Sci.USA, 97, 2000
1FLK
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BU of 1flk by Molmil
MOLECULAR BASIS FOR CD40 SIGNALING MEDIATED BY TRAF3
Descriptor: TNF RECEPTOR ASSOCIATED FACTOR 3
Authors:Ni, C.-Z, Welsh, K, Leo, E, Chiou, C.-K, Wu, H, Reed, J.C, Ely, K.R.
Deposit date:2000-08-14
Release date:2000-10-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for CD40 signaling mediated by TRAF3.
Proc.Natl.Acad.Sci.USA, 97, 2000
2GKW
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BU of 2gkw by Molmil
Key contacts promote recongnito of BAFF-R by TRAF3
Descriptor: TNF receptor-associated factor 3, Tumor necrosis factor receptor superfamily member 13C
Authors:Ely, K.R.
Deposit date:2006-04-03
Release date:2006-04-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation.
J.Immunol., 173, 2004
2I39
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BU of 2i39 by Molmil
Crystal structure of Vaccinia virus N1L protein
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Protein N1
Authors:Aoyagi, M, Aleshin, A.E, Stec, B, Liddington, R.C.
Deposit date:2006-08-17
Release date:2006-11-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein.
Protein Sci., 16, 2007
3H16
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BU of 3h16 by Molmil
Crystal structure of a bacteria TIR domain, PdTIR from Paracoccus denitrificans
Descriptor: SULFATE ION, TIR protein
Authors:Chan, S.L, Low, L.Y, Santelli, E, Pascual, J.
Deposit date:2009-04-11
Release date:2009-06-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Mimicry in Innate Immunity: CRYSTAL STRUCTURE OF A BACTERIAL TIR DOMAIN.
J.Biol.Chem., 284, 2009
4EWI
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BU of 4ewi by Molmil
Crystal structure of the NLRP4 Pyrin domain
Descriptor: CHLORIDE ION, NACHT, LRR and PYD domains-containing protein 4, ...
Authors:Eibl, C, Hessenberger, M, Puehringer, S, Page, R, Diederichs, K, Peti, W.
Deposit date:2012-04-27
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural and Functional Analysis of the NLRP4 Pyrin Domain.
Biochemistry, 51, 2012
1RCW
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BU of 1rcw by Molmil
Crystal structure of CT610 from Chlamydia trachomatis
Descriptor: CT610, FE (III) ION
Authors:Schwarzenbacher, R, Liddington, R.C.
Deposit date:2003-11-04
Release date:2004-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Chlamydia protein CADD reveals a redox enzyme that modulates host cell apoptosis.
J.Biol.Chem., 279, 2004

217705

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