Author results

1PBR
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STRUCTURE OF 16S RIBOSOMAL RNA, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:16S RIBOSOMAL RNA, 2-amino-2-deoxy-alpha-D-glucopyranose, 2-DEOXYSTREPTAMINE, ...
Authors:Fourmy, D., Recht, M.I., Blanchard, S., Puglisi, J.D.
Deposit date:1996-09-12
Release date:1997-09-17
Last modified:2013-01-16
Method:SOLUTION NMR
Cite:Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic.
Science, 274, 1996
2QBX
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EPHB2/SNEW ANTAGONISTIC PEPTIDE COMPLEX
Descriptor:Ephrin type-B receptor 2, antagonistic peptide, SULFATE ION
Authors:Chrencik, J.E., Brooun, A., Recht, M.I., Nicola, G., Pasquale, E.B., Kuhn, P., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
Deposit date:2007-06-18
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition.
J.Biol.Chem., 282, 2007
3TVX
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THE STRUCTURE OF PDE4A WITH PENTOXIFYLLINE AT 2.84A RESOLUTION
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4A, ZINC ION, MAGNESIUM ION, ...
Authors:Badger, J., Sridhar, V.
Deposit date:2011-09-20
Release date:2012-01-25
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Fragment-Based Screening for Inhibitors of PDE4A Using Enthalpy Arrays and X-ray Crystallography.
J Biomol Screen, 17, 2012
4LKQ
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT017
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 4-amino-1,7-dihydro-6H-pyrazolo[3,4-d]pyrimidine-6-thione, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-08
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LLJ
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT214
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 2H-isoindole-1,3-diamine, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LLK
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT217
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 2-methylquinazolin-4(3H)-one, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LLP
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT401
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 4-amino-2-methylphenol, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LLX
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT434
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 4,6-dimethylpyrimidin-2-amine, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LM0
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT448
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 5-NITROINDAZOLE, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LM1
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT450
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 5-nitroquinoline, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LM2
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT462
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 2,3-dihydro-1,4-benzodioxin-6-ylmethanol, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LM3
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT464
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethanone, NICKEL (II) ION, ...
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LM4
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT902
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, quinazolin-4(1H)-one, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-10
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4MRW
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT0120 (7-CHLOROQUINOLIN-4-OL)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 7-chloroquinolin-4-ol, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., NIenaber, V.
Deposit date:2013-09-17
Release date:2014-05-14
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014
4MRZ
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT0429 (4-METHYL-3-NITROPYRIDIN-2-AMINE)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 4-methyl-3-nitropyridin-2-amine, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-09-17
Release date:2014-05-14
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014
4MS0
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT0443 (6-CHLOROPYRIMIDINE-2,4-DIAMINE)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 6-chloropyrimidine-2,4-diamine, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-09-18
Release date:2014-05-14
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014
4MSA
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT0449 (5-NITRO-1H-BENZIMIDAZOLE)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 5-nitro-1H-benzimidazole, NICKEL (II) ION
Authors:Sridar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-09-18
Release date:2014-05-14
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014
4MSC
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT1595 (2-[(QUINOLIN-7-YLOXY)METHYL]QUINOLINE)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 2-[(quinolin-7-yloxy)methyl]quinoline, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-09-18
Release date:2014-05-14
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014
4MSE
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT1597 (2-({[(2S)-2-METHYL-2,3-DIHYDRO-1,3-BENZOTHIAZOL-5-YL]OXY}METHYL)QUINOLINE)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 2-{[(2-methyl-1,3-benzothiazol-5-yl)oxy]methyl}quinoline, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-09-18
Release date:2014-05-14
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014
4MSH
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT0143 ((2S)-4-CHLORO-2,3-DIHYDRO-1,3-BENZOTHIAZOL-2-AMINE)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 4-chloro-1,3-benzothiazol-2-amine, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-09-18
Release date:2014-05-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014
4MSN
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT0451 (8-NITROQUINOLINE)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 8-nitroquinoline, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-09-18
Release date:2014-05-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014
2BBA
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CRYSTAL STRUCTURE AND THERMODYNAMIC CHARACTERIZATION OF THE EPHB4 RECEPTOR IN COMPLEX WITH AN EPHRIN-B2 ANTAGONIST PEPTIDE REVEALS THE DETERMINANTS FOR RECEPTOR SPECIFICITY.
Descriptor:Ephrin type-B receptor 4, Agonist peptide, SULFATE ION
Authors:Chrencik, J.E., Kuhn, P., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
Deposit date:2005-10-17
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity.
Structure, 14, 2006
2HLE
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STRUCTURAL AND BIOPHYSICAL CHARACTERIZATION OF THE EPHB4-EPHRINB2 PROTEIN PROTEIN INTERACTION AND RECEPTOR SPECIFICITY.
Descriptor:Ephrin type-B receptor 4, Ephrin-B2
Authors:Chrencik, J.E., Brooun, A., Kuhn, P., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
Deposit date:2006-07-06
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and Biophysical Characterization of the EphB4-EphrinB2 Protein-Protein Interaction and Receptor Specificity.
J.Biol.Chem., 281, 2006
3RF2
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CRYSTAL STRUCTURE OF 30S RIBOSOMAL PROTEIN S8 FROM AQUIFEX AEOLICUS
Descriptor:30S ribosomal protein S8, SULFATE ION
Authors:Menichelli, E., Williamson, J.R.
Deposit date:2011-04-05
Release date:2011-11-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:The Structure of Aquifex aeolicus Ribosomal Protein S8 Reveals a Unique Subdomain that Contributes to an Extremely Tight Association with 16S rRNA.
J.Mol.Biol., 415, 2012