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7T5Q
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BU of 7t5q by Molmil
Cryo-EM Structure of a Transition State of Arp2/3 Complex Activation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, van Eeuwen, T, Boczkowska, M, Dominguez, R.
Deposit date:2021-12-13
Release date:2023-06-14
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of an Arp2/3 complex mini-branch capped by capping protein (CapZ)
To Be Published
4EDQ
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BU of 4edq by Molmil
MBP-fusion protein of myosin-binding protein c residues 149-269
Descriptor: Maltose-binding periplasmic protein,Myosin-binding protein C, cardiac-type chimeric protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2012-03-27
Release date:2013-03-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:MBP-fusion protein of myosin-binding protein c residues 149-269
To be Published
6NBW
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BU of 6nbw by Molmil
Ternary Complex of Beta/Gamma-Actin with Profilin and AnCoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-10
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NAS
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BU of 6nas by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and AcCoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-06
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NBE
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BU of 6nbe by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and CoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-07
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
3M3N
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BU of 3m3n by Molmil
Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rebowski, G, Namgoong, S, Dominguez, R.
Deposit date:2010-03-09
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (7 Å)
Cite:Structure of a longitudinal actin dimer assembled by tandem w domains: implications for actin filament nucleation.
J.Mol.Biol., 403, 2010
4Z94
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BU of 4z94 by Molmil
Actin Complex With a Chimera of Tropomodulin-1 and Leiomodin-1 Actin-Binding Site 2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2015-04-09
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.
Nat Commun, 6, 2015
4Z79
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BU of 4z79 by Molmil
Leiomodin-1 Actin-Binding Site 2 (ABS2)
Descriptor: CHLORIDE ION, GLYCEROL, Leiomodin-1 Actin-Binding Site 2 (ABS2), ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2015-04-06
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.
Nat Commun, 6, 2015
7JPN
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BU of 7jpn by Molmil
Cryo-EM structure of Arpin-bound Arp2/3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ...
Authors:van Eeuwen, T, Fregoso, F.E, Dominguez, R, Zimmet, A, Boczkowska, M, Rebowski, G.
Deposit date:2020-08-09
Release date:2022-02-09
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Molecular mechanism of Arp2/3 complex inhibition by Arpin.
Nat Commun, 13, 2022
4Z8G
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BU of 4z8g by Molmil
Chimera of Tropomodulin-1 and Leiomodin-1 Actin-Binding Site 2 (TL1 ABS2)
Descriptor: NICKEL (II) ION, Tropomodulin-1, Leiomodin-1 chimera (TP1 ABS2)
Authors:Boczkowska, M, Rebowski, G, Dominguez, R.
Deposit date:2015-04-08
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.
Nat Commun, 6, 2015
2PBD
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BU of 2pbd by Molmil
Ternary complex of profilin-actin with the poly-PRO-GAB domain of VASP*
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Ferron, F, Rebowski, G, Dominguez, R.
Deposit date:2007-03-28
Release date:2007-11-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP
Embo J., 26, 2007
2PAV
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BU of 2pav by Molmil
Ternary complex of Profilin-Actin with the Last Poly-Pro of Human VASP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Ferron, F, Rebowski, G, Dominguez, R.
Deposit date:2007-03-27
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP.
Embo J., 26, 2007
3OK8
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BU of 3ok8 by Molmil
I-BAR OF PinkBAR
Descriptor: Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2, GLYCEROL
Authors:Boczkowska, M, Rebowski, G, Saarikangas, J, Lappalainen, P, Dominguez, R.
Deposit date:2010-08-24
Release date:2011-07-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures.
Nat.Struct.Mol.Biol., 18, 2011
3M1F
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BU of 3m1f by Molmil
Crosslinked complex of actin with first W domain of Vibrio parahaemolyticus VopL
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Namgoong, S, Dominguez, R.
Deposit date:2010-03-04
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structure of a longitudinal actin dimer assembled by tandem w domains: implications for actin filament nucleation.
J.Mol.Biol., 403, 2010
8TAH
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BU of 8tah by Molmil
Cryo-EM structure of Cortactin-bound to Arp2/3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ...
Authors:Fregoso, F.E, van Eeuwen, T, Dominguez, R.
Deposit date:2023-06-27
Release date:2023-09-27
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins.
Nat Commun, 14, 2023
1N2D
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BU of 1n2d by Molmil
Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin
Descriptor: IQ2 AND IQ3 MOTIFS FROM MYO2P, A CLASS V MYOSIN, Myosin Light Chain
Authors:Terrak, M, Wu, G, Stafford, W.F, Lu, R.C, Dominguez, R.
Deposit date:2002-10-22
Release date:2003-11-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the light chain-binding domain of myosin V.
Proc.Natl.Acad.Sci.USA, 102, 2005
5WFN
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BU of 5wfn by Molmil
Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT)
Descriptor: Actin-5C, Leiomodin-2, MAGNESIUM ION, ...
Authors:Yurtsever, Z, Eck, M.J, Dominguez, R.
Deposit date:2017-07-12
Release date:2017-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination
Biophys.J., 113, 2017
3RYL
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BU of 3ryl by Molmil
Dimerization domain of Vibrio parahemolyticus VopL
Descriptor: protein VPA1370
Authors:Namgoong, S, Dominguez, R.
Deposit date:2011-05-11
Release date:2011-08-31
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism of actin filament nucleation by Vibrio VopL and implications for tandem W domain nucleation.
Nat.Struct.Mol.Biol., 18, 2011
6UHC
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BU of 6uhc by Molmil
CryoEM structure of human Arp2/3 complex with bound NPFs
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ...
Authors:Zimmet, A, van Eeuwen, T, Dominguez, R.
Deposit date:2019-09-27
Release date:2020-07-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism.
Sci Adv, 6, 2020
8F8Q
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BU of 8f8q by Molmil
Cryo-EM structure of the CapZ-capped barbed end of F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Carman, P.J, Barrie, K.R, Dominguez, R.
Deposit date:2022-11-22
Release date:2023-06-07
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Structures of the free and capped ends of the actin filament.
Science, 380, 2023
8F8P
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BU of 8f8p by Molmil
Cryo-EM structure of F-actin in the ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Carman, P.J, Barrie, K.R, Dominguez, R.
Deposit date:2022-11-22
Release date:2023-06-07
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Structures of the free and capped ends of the actin filament.
Science, 380, 2023
8F8R
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BU of 8f8r by Molmil
Cryo-EM structure of the free barbed end of F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Carman, P.J, Barrie, K.R, Dominguez, R.
Deposit date:2022-11-22
Release date:2023-06-07
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of the free and capped ends of the actin filament.
Science, 380, 2023
8F8T
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BU of 8f8t by Molmil
Cryo-EM structure of the Tropomodulin-capped pointed end of F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Carman, P.J, Barrie, K.R, Dominguez, R.
Deposit date:2022-11-22
Release date:2023-06-07
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structures of the free and capped ends of the actin filament.
Science, 380, 2023
8F8S
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BU of 8f8s by Molmil
Cryo-EM structure of the free pointed end of F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Carman, P.J, Barrie, K.R, Dominguez, R.
Deposit date:2022-11-22
Release date:2023-06-07
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Structures of the free and capped ends of the actin filament.
Science, 380, 2023
2Q97
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BU of 2q97 by Molmil
Complex of mammalian actin with toxofilin from toxoplasma gondii
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Lee, S.H, Dominguez, R.
Deposit date:2007-06-12
Release date:2007-10-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Toxofilin from Toxoplasma gondii forms a ternary complex with an antiparallel actin dimer
Proc.Natl.Acad.Sci.Usa, 104, 2007

 

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