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5M63
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BU of 5m63 by Molmil
Crystal structure of group B Streptococcus type III DP2 oligosaccharide bound to Fab NVS-1-19-5
Descriptor: (2~{R},3~{R},4~{S},5~{S})-2-[bis(oxidanyl)methyl]-5-(hydroxymethyl)oxolane-3,4-diol, 1,2-ETHANEDIOL, H chain of Fab NVS-1-19-5, ...
Authors:Carboni, F, Adamo, R, Veggi, D, Rappuoli, R, Malito, E, Margarit, I.R, Berti, F.
Deposit date:2016-10-24
Release date:2017-05-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4E9L
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BU of 4e9l by Molmil
FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections
Descriptor: Attaching and effacing protein, pathogenesis factor
Authors:Spraggon, G, Nesta, B, Alteri, C, Gomes Moriel, D, Rosini, R, Veggi, D, Smith, S, Bertoldi, I, Pastorello, I, Ferlenghi, I, Fontana, M.R, Frankel, G, Mobley, H.L.T, Rappuoli, R, Pizza, M, Serino, L, Soriana, M.
Deposit date:2012-03-21
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections.
MBio, 3, 2012
1JI4
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BU of 1ji4 by Molmil
NAP protein from helicobacter pylori
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, FE (III) ION, NEUTROPHIL-ACTIVATING PROTEIN A, ...
Authors:Zanotti, G, Papinutto, E, Dundon, W.G, Battistutta, R, Seveso, M, Del Giudice, G, Rappuoli, R, Montecucco, C.
Deposit date:2001-06-29
Release date:2002-10-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structure of the Neutrophil-activating Protein from Helicobacter pylori
J.Mol.Biol., 323, 2002
1YS5
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BU of 1ys5 by Molmil
Solution structure of the antigenic domain of GNA1870 of Neisseria meningitidis
Descriptor: lipoprotein
Authors:Cantini, F, Savino, S, Masignani, V, Pizza, M, Scarselli, M, Swennen, E, Romagnoli, G, Veggi, D, Banci, L, Rappuoli, R.
Deposit date:2005-02-07
Release date:2006-02-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis
J.Biol.Chem., 281, 2006
3RKI
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BU of 3rki by Molmil
Structural basis for immunization with post-fusion RSV F to elicit high neutralizing antibody titers
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Swanson, K.A, Settembre, E.C, Shaw, C.A, Dey, A.K, Rappuoli, R, Mandl, C.W, Dormitzer, P.D, Carfi, A.
Deposit date:2011-04-18
Release date:2011-05-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers.
Proc.Natl.Acad.Sci.USA, 108, 2011
2KC0
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BU of 2kc0 by Molmil
Solution structure of the factor H binding protein
Descriptor: lipoprotein
Authors:Cantini, F, Veggi, D, Dragonetti, S, Savino, S, Scarselli, M, Romagnoli, G, Pizza, M, Banci, L, Rappuoli, R.
Deposit date:2008-12-13
Release date:2009-02-17
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidis
J.Biol.Chem., 284, 2009
2X9W
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BU of 2x9w by Molmil
STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor: CELL WALL SURFACE ANCHOR FAMILY PROTEIN, GLYCEROL
Authors:Spraggon, G, Koesema, E, Scarselli, M, Malito, E, Biagini, M, Norais, N, Emolo, C, Barocchi, M.A, Giusti, F, Hilleringmann, M, Rappuoli, R, Lesley, S, Covacci, A, Masignani, V, Ferlenghi, I.
Deposit date:2010-03-25
Release date:2010-06-30
Last modified:2019-10-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus Pneumoniae Pilus.
Plos One, 5, 2010
2X9Z
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BU of 2x9z by Molmil
STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor: CELL WALL SURFACE ANCHOR FAMILY PROTEIN
Authors:Spraggon, G, Koesema, E, Scarselli, M, Malito, E, Biagini, M, Norais, N, Emolo, C, Barocchi, M.A, Giusti, F, Hilleringmann, M, Rappuoli, R, Lesley, S, Covacci, A, Masignani, V, Ferlenghi, I.
Deposit date:2010-03-25
Release date:2010-06-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus Pneumoniae Pilus.
Plos One, 5, 2010
2X9Y
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BU of 2x9y by Molmil
STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor: CELL WALL SURFACE ANCHOR FAMILY PROTEIN
Authors:Spraggon, G, Koesema, E, Scarselli, M, Malito, E, Biagini, M, Norais, N, Emolo, C, Barocchi, M.A, Giusti, F, Hilleringmann, M, Rappuoli, R, Lesley, S, Covacci, A, Masignani, V, Ferlenghi, I.
Deposit date:2010-03-25
Release date:2010-06-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus Pneumoniae Pilus.
Plos One, 5, 2010
2X9X
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BU of 2x9x by Molmil
STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor: CELL WALL SURFACE ANCHOR FAMILY PROTEIN, IMIDAZOLE, SODIUM ION
Authors:Spraggon, G, Koesema, E, Scarselli, M, Malito, E, Biagini, M, Norais, N, Emolo, C, Barocchi, M.A, Giusti, F, Hilleringmann, M, Rappuoli, R, Lesley, S, Covacci, A, Masignani, V, Ferlenghi, I.
Deposit date:2010-03-25
Release date:2010-06-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus Pneumoniae Pilus.
Plos One, 5, 2010
1HTL
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BU of 1htl by Molmil
MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
Descriptor: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1995-02-15
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli.
Nat.Struct.Biol., 2, 1995
6Y54
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BU of 6y54 by Molmil
Crystal structure of a Neisseria meningitidis serogroup A capsular oligosaccharide bound to a functional Fab
Descriptor: 1,2-ETHANEDIOL, Fab A1.1 H chain, Fab A1.1 L chain, ...
Authors:Dello Iacono, L, Henriques, P, Adamo, R.
Deposit date:2020-02-24
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharide.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XZW
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BU of 6xzw by Molmil
Crystal structure of the meningococcal vaccine antigen fHbp in complex with a cross-reactive human Fab.
Descriptor: 1,2-ETHANEDIOL, Fab 4B3 (heavy chain), Fab 4B3 (light chain), ...
Authors:Veggi, D, Cozzi, R.
Deposit date:2020-02-05
Release date:2020-10-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp.
Plos Pathog., 16, 2020
1LT4
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BU of 1lt4 by Molmil
HEAT-LABILE ENTEROTOXIN MUTANT S63K
Descriptor: HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Van Den Akker, F, Hol, W.G.J.
Deposit date:1997-04-14
Release date:1997-06-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
Protein Sci., 6, 1997
1LTG
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BU of 1ltg by Molmil
THE ARG7LYS MUTANT OF HEAT-LABILE ENTEROTOXIN EXHIBITS GREAT FLEXIBILITY OF ACTIVE SITE LOOP 47-56 OF THE A SUBUNIT
Descriptor: HEAT-LABILE ENTEROTOXIN
Authors:Van Den Akker, F, Hol, W.G.J.
Deposit date:1995-06-13
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
Biochemistry, 34, 1995
2YPV
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BU of 2ypv by Molmil
Crystal structure of the Meningococcal vaccine antigen factor H binding protein in complex with a bactericidal antibody
Descriptor: 1,2-ETHANEDIOL, FAB 12C1, LIPOPROTEIN
Authors:Malito, E, Veggi, D, Bottomley, M.J.
Deposit date:2012-11-01
Release date:2013-02-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Defining a Protective Epitope on Factor H Binding Protein, a Key Meningococcal Virulence Factor and Vaccine Antigen.
Proc.Natl.Acad.Sci.USA, 110, 2013
4CJD
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BU of 4cjd by Molmil
Crystal structure of Neisseria meningitidis trimeric autotransporter and vaccine antigen NadA
Descriptor: IODIDE ION, NADA
Authors:Malito, E, Biancucci, M, Spraggon, G, Bottomley, M.J.
Deposit date:2013-12-19
Release date:2014-11-26
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.056 Å)
Cite:Structure of the Meningococcal Vaccine Antigen Nada and Epitope Mapping of a Bactericidal Antibody.
Proc.Natl.Acad.Sci.USA, 111, 2014
2FJC
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BU of 2fjc by Molmil
Crystal structure of antigen TpF1 from Treponema pallidum
Descriptor: Antigen TpF1, FE (III) ION
Authors:Thumiger, A, Polenghi, A, Papinutto, E, Battistutta, R, Montecucco, C, Zanotti, G.
Deposit date:2006-01-02
Release date:2006-01-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of antigen TpF1 from Treponema pallidum.
Proteins, 62, 2006
7S6L
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BU of 7s6l by Molmil
J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (conformation 3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2021-09-14
Release date:2022-05-11
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S6I
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BU of 7s6i by Molmil
SARS-CoV-2-6P-Mut2 S protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2021-09-14
Release date:2022-05-11
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S6K
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BU of 7s6k by Molmil
J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2021-09-14
Release date:2022-05-11
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S6J
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BU of 7s6j by Molmil
J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2021-09-14
Release date:2022-05-11
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SBU
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BU of 7sbu by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a highly potent antibody J08 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, J08 Fab heavy chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2021-09-25
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
2XTL
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BU of 2xtl by Molmil
Structure of the major pilus backbone protein from Streptococcus Agalactiae
Descriptor: CELL WALL SURFACE ANCHOR FAMILY PROTEIN, POTASSIUM ION
Authors:Rinauda, D, Gourlay, L.J, Soriano, M, Grandi, G, Bolognesi, M.
Deposit date:2010-10-11
Release date:2011-07-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure-Based Approach to Rationally Design a Chimeric Protein for an Effective Vaccine Against Group B Streptococcus Infections.
Proc.Natl.Acad.Sci.USA, 108, 2011
4AE1
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BU of 4ae1 by Molmil
Crystal structure of diphtheria toxin mutant CRM197 in complex with nicotinamide
Descriptor: DIPHTHERIA TOXIN, NICOTINAMIDE
Authors:Malito, E, Spraggon, G.
Deposit date:2012-01-04
Release date:2012-03-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.078 Å)
Cite:Structural Basis for Lack of Toxicity of the Diphtheria Toxin Mutant Crm197.
Proc.Natl.Acad.Sci.USA, 109, 2012

 

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