Author results

1JI4
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NAP PROTEIN FROM HELICOBACTER PYLORI
Descriptor:NEUTROPHIL-ACTIVATING PROTEIN A, FE (III) ION, UNKNOWN ATOM OR ION, ...
Authors:Zanotti, G., Papinutto, E., Dundon, W.G., Battistutta, R., Seveso, M., Del Giudice, G., Rappuoli, R., Montecucco, C.
Deposit date:2001-06-29
Release date:2002-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structure of the Neutrophil-activating Protein from Helicobacter pylori
J.Mol.Biol., 323, 2002
4E9L
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FDEC, A NOVEL BROADLY CONSERVED ESCHERICHIA COLI ADHESIN ELICITING PROTECTION AGAINST URINARY TRACT INFECTIONS
Descriptor:Attaching and effacing protein, pathogenesis factor
Authors:Spraggon, G., Nesta, B., Alteri, C., Gomes Moriel, D., Rosini, R., Veggi, D., Smith, S., Bertoldi, I., Pastorello, I., Ferlenghi, I., Fontana, M.R., Frankel, G., Mobley, H.L.T., Rappuoli, R., Pizza, M., Serino, L., Soriana, M.
Deposit date:2012-03-21
Release date:2012-04-25
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections.
MBio, 3, 2012
5M63
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CRYSTAL STRUCTURE OF GROUP B STREPTOCOCCUS TYPE III DP2 OLIGOSACCHARIDE BOUND TO FAB NVS-1-19-5
Descriptor:H chain of Fab NVS-1-19-5, L chain of Fab NVS-1-19-5, 1,2-ETHANEDIOL, ...
Authors:Carboni, F., Adamo, R., Veggi, D., Rappuoli, R., Malito, E., Margarit, I.R., Berti, F.
Deposit date:2016-10-24
Release date:2017-05-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1YS5
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SOLUTION STRUCTURE OF THE ANTIGENIC DOMAIN OF GNA1870 OF NEISSERIA MENINGITIDIS
Descriptor:lipoprotein
Authors:Cantini, F., Savino, S., Masignani, V., Pizza, M., Scarselli, M., Swennen, E., Romagnoli, G., Veggi, D., Banci, L., Rappuoli, R.
Deposit date:2005-02-07
Release date:2006-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis
J.Biol.Chem., 281, 2006
2KC0
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SOLUTION STRUCTURE OF THE FACTOR H BINDING PROTEIN
Descriptor:lipoprotein
Authors:Cantini, F., Veggi, D., Dragonetti, S., Savino, S., Scarselli, M., Romagnoli, G., Pizza, M., Banci, L., Rappuoli, R.
Deposit date:2008-12-13
Release date:2009-02-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidis
J.Biol.Chem., 284, 2009
2X9W
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STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:CELL WALL SURFACE ANCHOR FAMILY PROTEIN, GLYCEROL
Authors:Spraggon, G., Koesema, E., Scarselli, M., Malito, E., Biagini, M., Norais, N., Emolo, C., Barocchi, M.A., Giusti, F., Hilleringmann, M., Rappuoli, R., Lesley, S., Covacci, A., Masignani, V., Ferlenghi, I.
Deposit date:2010-03-25
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus Pneumoniae Pilus.
Plos One, 5, 2010
2X9X
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STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:CELL WALL SURFACE ANCHOR FAMILY PROTEIN, IMIDAZOLE, SODIUM ION
Authors:Spraggon, G., Koesema, E., Scarselli, M., Malito, E., Biagini, M., Norais, N., Emolo, C., Barocchi, M.A., Giusti, F., Hilleringmann, M., Rappuoli, R., Lesley, S., Covacci, A., Masignani, V., Ferlenghi, I.
Deposit date:2010-03-25
Release date:2010-06-30
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus Pneumoniae Pilus.
Plos One, 5, 2010
2X9Y
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STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:CELL WALL SURFACE ANCHOR FAMILY PROTEIN
Authors:Spraggon, G., Koesema, E., Scarselli, M., Malito, E., Biagini, M., Norais, N., Emolo, C., Barocchi, M.A., Giusti, F., Hilleringmann, M., Rappuoli, R., Lesley, S., Covacci, A., Masignani, V., Ferlenghi, I.
Deposit date:2010-03-25
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus Pneumoniae Pilus.
Plos One, 5, 2010
2X9Z
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STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:CELL WALL SURFACE ANCHOR FAMILY PROTEIN
Authors:Spraggon, G., Koesema, E., Scarselli, M., Malito, E., Biagini, M., Norais, N., Emolo, C., Barocchi, M.A., Giusti, F., Hilleringmann, M., Rappuoli, R., Lesley, S., Covacci, A., Masignani, V., Ferlenghi, I.
Deposit date:2010-03-25
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus Pneumoniae Pilus.
Plos One, 5, 2010
3RKI
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STRUCTURAL BASIS FOR IMMUNIZATION WITH POST-FUSION RSV F TO ELICIT HIGH NEUTRALIZING ANTIBODY TITERS
Descriptor:Fusion glycoprotein F0, N-ACETYL-D-GLUCOSAMINE
Authors:Swanson, K.A., Settembre, E.C., Shaw, C.A., Dey, A.K., Rappuoli, R., Mandl, C.W., Dormitzer, P.D., Carfi, A.
Deposit date:2011-04-18
Release date:2011-05-18
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers.
Proc.Natl.Acad.Sci.USA, 108, 2011
1HTL
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MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
Descriptor:HEAT-LABILE ENTEROTOXIN, SUBUNIT B, SUBUNIT A
Authors:Merritt, E.A., Hol, W.G.J.
Deposit date:1995-02-15
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli.
Nat.Struct.Biol., 2, 1995
1LT4
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HEAT-LABILE ENTEROTOXIN MUTANT S63K
Descriptor:HEAT-LABILE ENTEROTOXIN, BETA-D-GALACTOSE, BETA-D-GLUCOSE
Authors:Van Den Akker, F., Hol, W.G.J.
Deposit date:1997-04-14
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
Protein Sci., 6, 1997
1LTG
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THE ARG7LYS MUTANT OF HEAT-LABILE ENTEROTOXIN EXHIBITS GREAT FLEXIBILITY OF ACTIVE SITE LOOP 47-56 OF THE A SUBUNIT
Descriptor:HEAT-LABILE ENTEROTOXIN
Authors:Van Den Akker, F., Hol, W.G.J.
Deposit date:1995-06-13
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
Biochemistry, 34, 1995
2XTL
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STRUCTURE OF THE MAJOR PILUS BACKBONE PROTEIN FROM STREPTOCOCCUS AGALACTIAE
Descriptor:CELL WALL SURFACE ANCHOR FAMILY PROTEIN, POTASSIUM ION
Authors:Rinauda, D., Gourlay, L.J., Soriano, M., Grandi, G., Bolognesi, M.
Deposit date:2010-10-11
Release date:2011-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure-Based Approach to Rationally Design a Chimeric Protein for an Effective Vaccine Against Group B Streptococcus Infections.
Proc.Natl.Acad.Sci.USA, 108, 2011
4CJD
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CRYSTAL STRUCTURE OF NEISSERIA MENINGITIDIS TRIMERIC AUTOTRANSPORTER AND VACCINE ANTIGEN NADA
Descriptor:NADA, IODIDE ION
Authors:Malito, E., Biancucci, M., Spraggon, G., Bottomley, M.J.
Deposit date:2013-12-19
Release date:2014-11-26
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.056 Å)
Cite:Structure of the Meningococcal Vaccine Antigen Nada and Epitope Mapping of a Bactericidal Antibody.
Proc.Natl.Acad.Sci.USA, 111, 2014
2Y7S
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STRUCTURE OF A DESIGNED MENINGOCOCCAL ANTIGEN (FACTOR H BINDING PROTEIN, MUTANT G1) INDUCING BROAD PROTECTIVE IMMUNITY
Descriptor:FACTOR H BINDING PROTEIN
Authors:Malito, E., Spraggon, G., Bottomley, M.J.
Deposit date:2011-02-01
Release date:2011-07-27
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity.
Sci.Transl.Med, 3, 2011
2YPV
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CRYSTAL STRUCTURE OF THE MENINGOCOCCAL VACCINE ANTIGEN FACTOR H BINDING PROTEIN IN COMPLEX WITH A BACTERICIDAL ANTIBODY
Descriptor:LIPOPROTEIN, FAB 12C1, 1,2-ETHANEDIOL
Authors:Malito, E., Veggi, D., Bottomley, M.J.
Deposit date:2012-11-01
Release date:2013-02-20
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Defining a Protective Epitope on Factor H Binding Protein, a Key Meningococcal Virulence Factor and Vaccine Antigen.
Proc.Natl.Acad.Sci.USA, 110, 2013
4AE0
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CRYSTAL STRUCTURE OF DIPHTHERIA TOXIN MUTANT CRM197
Descriptor:DIPHTHERIA TOXIN
Authors:Malito, E., Spraggon, G.
Deposit date:2012-01-04
Release date:2012-03-28
Last modified:2012-04-18
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Structural Basis for Lack of Toxicity of the Diphtheria Toxin Mutant Crm197.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AE1
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CRYSTAL STRUCTURE OF DIPHTHERIA TOXIN MUTANT CRM197 IN COMPLEX WITH NICOTINAMIDE
Descriptor:DIPHTHERIA TOXIN, NICOTINAMIDE
Authors:Malito, E., Spraggon, G.
Deposit date:2012-01-04
Release date:2012-03-28
Last modified:2012-04-18
Method:X-RAY DIFFRACTION (2.078 Å)
Cite:Structural Basis for Lack of Toxicity of the Diphtheria Toxin Mutant Crm197.
Proc.Natl.Acad.Sci.USA, 109, 2012
2FJC
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CRYSTAL STRUCTURE OF ANTIGEN TPF1 FROM TREPONEMA PALLIDUM
Descriptor:Antigen TpF1, FE (III) ION
Authors:Thumiger, A., Polenghi, A., Papinutto, E., Battistutta, R., Montecucco, C., Zanotti, G.
Deposit date:2006-01-02
Release date:2006-01-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of antigen TpF1 from Treponema pallidum.
Proteins, 62, 2006
1O9R
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THE X-RAY CRYSTAL STRUCTURE OF AGROBACTERIUM TUMEFACIENS DPS, A MEMBER OF THE FAMILY THAT PROTECT DNA WITHOUT BINDING
Descriptor:AGROBACTERIUM TUMEFACIENS DPS, FE (III) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Ilari, A., Ceci, P., Chiancone, E.
Deposit date:2002-12-18
Release date:2003-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Dps Protein of Agrobacterium Tumefaciens Does not Bind to DNA But Protects It Toward Oxidative Cleavage: X-Ray Crystal Structure, Iron Binding, and Hydroxyl-Radical Scavenging Properties
J.Biol.Chem., 278, 2003