Author results

2WVW
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CRYO-EM STRUCTURE OF THE RBCL-RBCX COMPLEX
Descriptor:RIBULOSE BISPHOSPHATE CARBOXYLASE LARGE CHAIN, RBCX PROTEIN
Authors:Liu, C., Young, A.L., Starling-Windhof, A., Bracher, A., Saschenbrecker, S., Rao, B.V., Rao, K.V., Berninghausen, O., Mielke, T., Hartl, F.U., Beckmann, R., Hayer-Hartl, M.
Deposit date:2009-10-20
Release date:2010-01-19
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Coupled Chaperone Action in Folding and Assembly of Hexadecameric Rubisco
Nature, 463, 2010
1KC5
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CRYSTAL STRUCTURE OF ANTIBODY PC287 IN COMPLEX WITH PS1 PEPTIDE
Descriptor:PC287 Immunoglobulin, PS1 peptide
Authors:Nair, D.T., Singh, K., Siddiqui, Z., Nayak, B.P., Rao, K.V., Salunke, D.M.
Deposit date:2001-11-07
Release date:2002-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
1KCV
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CRYSTAL STRUCTURE OF ANTIBODY PC282
Descriptor:PC282 IMMUNOGLOBULIN
Authors:Nair, D.T., Singh, K., Siddiqui, Z., Nayak, B.P., Rao, K.V., Salunke, D.M.
Deposit date:2001-11-11
Release date:2002-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
2A6D
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CRYSTAL STRUCTURE ANALYSIS OF THE ANTI-ARSONATE GERMLINE ANTIBODY 36-65 IN COMPLEX WITH A PHAGE DISPLAY DERIVED DODECAPEPTIDE RLLIADPPSPRE
Descriptor:Germline antibody 36-65 Fab light chain, Germline antibody 36-65 Fab Heavy chain, Dodecapeptide, ...
Authors:Sethi, D.K., Agarwal, A., Manivel, V., Rao, K.V., Salunke, D.M.
Deposit date:2005-07-02
Release date:2006-06-13
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.
Immunity, 24, 2006
2A6I
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CRYSTAL STRUCTURE ANALYSIS OF THE ANTI-ARSONATE GERMLINE ANTIBODY 36-65 IN COMPLEX WITH A PHAGE DISPLAY DERIVED DODECAPEPTIDE KLASIPTHTSPL
Descriptor:Germline antibody 36-65 Fab light chain, Germline antibody 36-65 Fab heavy chain, Dodecapeptide: KLASIPTHTSPL
Authors:Sethi, D.K., Agarwal, A., Manivel, V., Rao, K.V., Salunke, D.M.
Deposit date:2005-07-02
Release date:2006-06-13
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.
Immunity, 24, 2006
2A6J
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CRYSTAL STRUCTURE ANALYSIS OF THE ANTI-ARSONATE GERMLINE ANTIBODY 36-65
Descriptor:Germline antibody 36-65 Fab light chain, Germline antibody 36-65 Fab heavy chain
Authors:Sethi, D.K., Agarwal, A., Manivel, V., Rao, K.V., Salunke, D.M.
Deposit date:2005-07-02
Release date:2006-06-13
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.
Immunity, 24, 2006
2A6K
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CRYSTAL STRUCTURE ANALYSIS OF THE GERMLINE ANTIBODY 36-65 FAB IN COMPLEX WITH THE DODECAPEPTIDE SLGDNLTNHNLR
Descriptor:Germline antibody 36-65 Fab light chain, Germline antibody 36-65 Fab heavy chain, DODECAPEPTIDE: SLGDNLTNHNLR
Authors:Sethi, D.K., Agarwal, A., Manivel, V., Rao, K.V., Salunke, D.M.
Deposit date:2005-07-03
Release date:2006-06-13
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.
Immunity, 24, 2006
5DQC
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CO-CRYSTAL OF BACE1 WITH COMPOUND 0211
Descriptor:Beta-secretase 1, N-[(2S,3R)-3-hydroxy-4-({(2S,3S)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide
Authors:Ghosh, A.K., Bhavanam, S.R., Yen, T.-C., Cardenas, E.L., Rao, K.V., Downs, D., Huang, X., Tang, J., Mescar, A.D.
Deposit date:2015-09-14
Release date:2016-02-17
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (2.4651 Å)
Cite:Design of Potent and Highly Selective Inhibitors for Human beta-Secretase 2 (Memapsin 1), a Target for Type 2 Diabetes.
Chem Sci, 7, 2016
1KCS
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CRYSTAL STRUCTURE OF ANTIBODY PC282 IN COMPLEX WITH PS1 PEPTIDE
Descriptor:PC282 IMMUNOGLOBULIN, PS1 peptide
Authors:Nair, D.T., Singh, K., Siddiqui, Z., Nayak, B.P., Rao, K.V.S., Salunke, D.M.
Deposit date:2001-11-11
Release date:2002-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
1KCU
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CRYSTAL STRUCTURE OF ANTIBODY PC287
Descriptor:PC287 IMMUNOGLOBULIN
Authors:Nair, D.T., Singh, K., Siddiqui, Z., Nayak, B.P., Rao, K.V.S., Salunke, D.M.
Deposit date:2001-11-11
Release date:2002-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
2PEI
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CRYSTAL STRUCTURE OF SELENOMETHIONINE-LABELED RBCX
Descriptor:ORF134
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEJ
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CRYSTAL STRUCTURE OF RBCX POINT MUTANT Y17A/Y20L
Descriptor:ORF134
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEK
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CRYSTAL STRUCTURE OF RBCX POINT MUTANT Q29A
Descriptor:ORF134
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEM
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CRYSTAL STRUCTURE OF RBCX IN COMPLEX WITH SUBSTRATE
Descriptor:ORF134, RbcL
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEN
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CRYSTAL STRUCTURE OF RBCX, CRYSTAL FORM I
Descriptor:ORF134
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEO
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CRYSTAL STRUCTURE OF RBCX FROM ANABAENA CA
Descriptor:RbcX protein
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEQ
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CRYSTAL STRUCTURE OF RBCX, CRYSTAL FORM II
Descriptor:ORF134
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
1KCR
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CRYSTAL STRUCTURE OF ANTIBODY PC283 IN COMPLEX WITH PS1 PEPTIDE
Descriptor:PC283 IMMUNOGLOBULIN, PS1 peptide
Authors:Nair, D.T., Singh, K., Sahu, N., Rao, K.V.S., Salunke, D.M.
Deposit date:2001-11-11
Release date:2002-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of an antibody bound to an immunodominant peptide epitope: novel features in peptide-antibody recognition.
J.Immunol., 165, 2000
3HYB
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CRYSTAL STRUCTURE OF RBCX FROM ANABAENA, CRYSTAL FORM II
Descriptor:RbcX protein, SULFATE ION
Authors:Bracher, A., Liu, C.
Deposit date:2009-06-22
Release date:2010-01-19
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Coupled chaperone action in folding and assembly of hexadecameric Rubisco.
Nature, 463, 2010
3RG6
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CRYSTAL STRUCTURE OF A CHAPERONE-BOUND ASSEMBLY INTERMEDIATE OF FORM I RUBISCO
Descriptor:Ribulose bisphosphate carboxylase large chain, RbcX protein
Authors:Bracher, A., Starling-Windhof, A., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2011-04-07
Release date:2011-07-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a chaperone-bound assembly intermediate of form I Rubisco.
Nat.Struct.Mol.Biol., 18, 2011
3MJ5
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SEVERE ACUTE RESPIRATORY SYNDROME-CORONAVIRUS PAPAIN-LIKE PROTEASE INHIBITORS: DESIGN, SYNTHESIS, PROTEIN-LIGAND X-RAY STRUCTURE AND BIOLOGICAL EVALUATION
Descriptor:Replicase polyprotein 1a, N-(1,3-benzodioxol-5-ylmethyl)-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, ZINC ION
Authors:Mesecar, A.D., Ratia, K.M., Pegan, S.D.
Deposit date:2010-04-12
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biological evaluation
J.Med.Chem., 53, 2010
3OK9
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CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH NEW OXATRICYCLIC DESIGNED INHIBITOR GRL-0519A
Descriptor:Protease, (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, SODIUM ION, ...
Authors:Wang, Y.-F., Agniswamy, J., Weber, I.T.
Deposit date:2010-08-24
Release date:2010-09-22
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Probing Multidrug-Resistance and Protein-Ligand Interactions with Oxatricyclic Designed Ligands in HIV-1 Protease Inhibitors.
Chemmedchem, 5, 2010
4HDB
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CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS D30N COMPLEXED WITH INHIBITOR GRL-0519
Descriptor:HIV-1 Protease, (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, SODIUM ION, ...
Authors:Zhang, H., Wang, Y.-F., Shen, C.H., Agniswamy, J., Weber, I.T.
Deposit date:2012-10-02
Release date:2013-08-14
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Novel P2 tris-tetrahydrofuran group in antiviral compound 1 (GRL-0519) fills the S2 binding pocket of selected mutants of HIV-1 protease.
J.Med.Chem., 56, 2013
4HDF
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CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS V82A COMPLEXED WITH INHIBITOR GRL-0519
Descriptor:HIV-1 Protease, CHLORIDE ION, (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate
Authors:Zhang, H., Wang, Y.-F., Weber, I.T.
Deposit date:2012-10-02
Release date:2013-08-14
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Novel P2 tris-tetrahydrofuran group in antiviral compound 1 (GRL-0519) fills the S2 binding pocket of selected mutants of HIV-1 protease.
J.Med.Chem., 56, 2013
4HDP
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CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS I50V COMPLEXED WITH INHIBITOR GRL-0519
Descriptor:HIV-1 Protease, (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, SODIUM ION, ...
Authors:Shen, C.H., Zhang, H., Weber, I.T.
Deposit date:2012-10-02
Release date:2013-08-14
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Novel P2 tris-tetrahydrofuran group in antiviral compound 1 (GRL-0519) fills the S2 binding pocket of selected mutants of HIV-1 protease.
J.Med.Chem., 56, 2013
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