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6E8J
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CRYSTAL STRUCTURE OF A BACTERIAL HOMOLOG TO HUMAN LYSOSOMAL TRANSPORTER, SPINSTER, IN INWARD-FACING AND OCCUPIED CONFORMATION
Descriptor:Major facilitator family transporter
Authors:Zhou, F., Yao, D., Rao, B., Zhang, L., Cao, Y.
Deposit date:2018-07-30
Release date:2019-08-14
Method:X-RAY DIFFRACTION (3.091 Å)
Cite:The Structure of a Bacterial Homolog to Human Lysosomal Transporter Spinster
To Be Published
6E9C
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SELENOMETHIONINE DERIVATIVE STRUCTURE OF A BACTERIAL HOMOLOG TO HUMAN LYSOSOMAL TRANSPORTER, SPINSTER
Descriptor:Major facilitator family transporter
Authors:Zhou, F., Yao, D., Rao, B., Zhang, L., Cao, Y.
Deposit date:2018-07-31
Release date:2019-08-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Structure of a Bacterial Homolog to Human Lysosomal Transporter Spinster
To Be Published
6EBA
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CRYSTAL STRUCTURE OF A BACTERIAL HOMOLOG TO HUMAN LYSOSOMAL TRANSPORTER, SPINSTER, IN INWARD-FACING AND UNOCCUPIED CONFORMATION
Descriptor:Major facilitator family transporter
Authors:Zhou, F., Yao, D., Rao, B., Zhang, L., Cao, Y.
Deposit date:2018-08-06
Release date:2019-08-21
Method:X-RAY DIFFRACTION (3.812 Å)
Cite:The Structure of a Bacterial Homolog to Human Lysosomal Transporter Spinster
To Be Published
2PEI
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CRYSTAL STRUCTURE OF SELENOMETHIONINE-LABELED RBCX
Descriptor:ORF134
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEJ
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CRYSTAL STRUCTURE OF RBCX POINT MUTANT Y17A/Y20L
Descriptor:ORF134
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEK
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CRYSTAL STRUCTURE OF RBCX POINT MUTANT Q29A
Descriptor:ORF134
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEM
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CRYSTAL STRUCTURE OF RBCX IN COMPLEX WITH SUBSTRATE
Descriptor:ORF134, RbcL
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEN
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CRYSTAL STRUCTURE OF RBCX, CRYSTAL FORM I
Descriptor:ORF134
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEO
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CRYSTAL STRUCTURE OF RBCX FROM ANABAENA CA
Descriptor:RbcX protein
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PEQ
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CRYSTAL STRUCTURE OF RBCX, CRYSTAL FORM II
Descriptor:ORF134
Authors:Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U., Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
1Z3L
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X-RAY CRYSTAL STRUCTURE OF A MUTANT RIBONUCLEASE S (F8ANB)
Descriptor:Ribonuclease pancreatic, S-Peptide, S-Protein, ...
Authors:Das, M., Vasudeva Rao, B., Ghosh, S., Varadarajan, R.
Deposit date:2005-03-14
Release date:2005-03-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Attempts to delineate the relative contributions of changes in hydrophobicity and packing to changes in stability of ribonuclease S mutants.
Biochemistry, 44, 2005
1Z3M
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CRYSTAL STRUCTURE OF MUTANT RIBONUCLEASE S (F8NVA)
Descriptor:Ribonuclease pancreatic, S-Peptide, S-protein, ...
Authors:Das, M., Vasudeva Rao, B., Ghosh, S., Varadarajan, R.
Deposit date:2005-03-14
Release date:2005-03-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Attempts to delineate the relative contributions of changes in hydrophobicity and packing to changes in stability of ribonuclease S mutants.
Biochemistry, 44, 2005
2OI0
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CRYSTAL STRUCTURE ANALYSIS 0F THE TNF-A COVERTING ENZYME (TACE) IN COMPLEXED WITH ARYL-SULFONAMIDE
Descriptor:TNF- a Converting Enzyme (TACE), ZINC ION, (3S)-1-{[4-(BUT-2-YN-1-YLOXY)PHENYL]SULFONYL}PYRROLIDINE-3-THIOL
Authors:Wei, Y., Rao, G.B., Bandarage, U.K.
Deposit date:2007-01-10
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel thiol-based TACE inhibitors: rational design, synthesis, and SAR of thiol-containing aryl sulfonamides
Bioorg.Med.Chem.Lett., 17, 2007
5AG4
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CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A THIAZOLIDINONE LIGAND
Descriptor:GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA, (2S)-3-(3-chlorophenyl)-2-(pyridin-2-yl)-1,3-thiazolidin-4-one
Authors:Robinson, D.A., Spinks, D., Smith, V.C., Thompson, S., Smith, A., Torrie, L.S., McElroy, S.P., Brand, S., Brenk, R., Frearson, J.A., Read, K.D., Wyatt, P.G., Gilbert, I.H.
Deposit date:2015-01-29
Release date:2015-10-07
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode.
Chemmedchem, 10, 2015
5AG5
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CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A THIAZOLIDINONE LIGAND
Descriptor:GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, (2R)-3-benzyl-2-(1H-indazol-5-yl)-1,3-thiazolidin-4-one, TETRADECANOYL-COA
Authors:Robinson, D.A., Spinks, D., Smith, V.C., Thompson, S., Smith, A., Torrie, L.S., McElroy, S.P., Brand, S., Brenk, R., Frearson, J.A., Read, K.D., Wyatt, P.G., Gilbert, I.H.
Deposit date:2015-01-29
Release date:2015-10-07
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode.
Chemmedchem, 10, 2015
5AG6
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CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A THIAZOLIDINONE LIGAND
Descriptor:GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, (2R)-2-(4-hydroxy-3-methoxyphenyl)-3-(pyridin-2-ylmethyl)-1,3-thiazolidin-4-one, TETRADECANOYL-COA
Authors:Robinson, D.A., Spinks, D., Smith, V.C., Thompson, S., Smith, A., Torrie, L.S., McElroy, S.P., Brand, S., Brenk, R., Frearson, J.A., Read, K.D., Wyatt, P.G., Gilbert, I.H.
Deposit date:2015-01-29
Release date:2015-10-07
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode.
Chemmedchem, 10, 2015
5AG7
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CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A BENZOMORPHOLINE LIGAND
Descriptor:GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, ethyl (3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetate, TETRADECANOYL-COA
Authors:Robinson, D.A., Spinks, D., Smith, V.C., Thompson, S., Smith, A., Torrie, L.S., McElroy, S.P., Brand, S., Brenk, R., Frearson, J.A., Read, K.D., Wyatt, P.G., Gilbert, I.H.
Deposit date:2015-01-29
Release date:2015-10-07
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode.
Chemmedchem, 10, 2015
5AGE
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CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A BENZOMORPHOLINONE LIGAND
Descriptor:GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, 4-[(5-methyl-1,2-oxazol-3-yl)methyl]-7-[4-(1-methylpiperidin-4-yl)butyl]-2H-1,4-benzoxazin-3(4H)-one, TETRADECANOYL-COA
Authors:Robinson, D.A., Spinks, D., Smith, V.C., Thompson, S., Smith, A., Torrie, L.S., McElroy, S.P., Brand, S., Brenk, R., Frearson, J.A., Read, K.D., Wyatt, P.G., Gilbert, I.H.
Deposit date:2015-01-29
Release date:2015-10-07
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode.
Chemmedchem, 10, 2015