1S9L
| NMR Solution Structure of a Parallel LNA Quadruplex | Descriptor: | 5'-((TLN)P*(LCG)P*(LCG)P*(LCG)P*(TLN))-3' | Authors: | Randazzo, A, Esposito, V, Ohlenschlager, O, Ramachandran, R, Mayola, L. | Deposit date: | 2004-02-05 | Release date: | 2004-06-29 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | NMR solution structure of a parallel LNA quadruplex. Nucleic Acids Res., 32, 2004
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2IDN
| NMR structure of a new modified Thrombin Binding Aptamer containing a 5'-5' inversion of polarity site | Descriptor: | 3'-D(P*GP*G*T)-5'-5'-D(P*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3' | Authors: | Randazzo, A, Martino, L, Virno, A, Mayol, L, Giancola, C. | Deposit date: | 2006-09-15 | Release date: | 2007-01-09 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | A new modified thrombin binding aptamer containing a 5'-5' inversion of polarity site. Nucleic Acids Res., 34, 2006
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2MKO
| G-triplex structure and formation propensity | Descriptor: | DNA_(5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*G)-3'), POTASSIUM ION | Authors: | Cerofolini, L, Fragai, M, Giachetti, A, Limongelli, V, Luchinat, C, Novellino, E, Parrinello, M, Randazzo, A. | Deposit date: | 2014-02-11 | Release date: | 2014-11-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | G-triplex structure and formation propensity. Nucleic Acids Res., 42, 2014
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2MKM
| G-triplex structure and formation propensity | Descriptor: | DNA_(5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*G)-3') | Authors: | Cerofolini, L, Fragai, M, Giachetti, A, Limongelli, V, Luchinat, C, Novellino, E, Parrinello, M, Randazzo, A. | Deposit date: | 2014-02-10 | Release date: | 2014-11-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | G-triplex structure and formation propensity. Nucleic Acids Res., 42, 2014
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2KVY
| NMR solution structure of the 4:1 complex between an uncharged distamycin A analogue and [d(TGGGGT)]4 | Descriptor: | 4-amino-1-methyl-N-{1-methyl-5-[(1-methyl-5-{[3-(methylamino)-3-oxopropyl]carbamoyl}-1H-pyrrol-3-yl)carbamoyl]-1H-pyrrol-3-yl}-1H-pyrrole-2-carboxamide, DNA (5'-D(*TP*GP*GP*GP*GP*T)-3') | Authors: | Cosconati, S, Marinelli, L, Trotta, R, Virno, A, De Tito, S, Romagnoli, R, Pagano, B, Limongelli, V, Giancola, C, Baraldi, P, Mayol, L, Novellino, E, Randazzo, A. | Deposit date: | 2010-03-29 | Release date: | 2010-05-26 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle. J.Am.Chem.Soc., 132, 2010
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7PNL
| Complex between monomolecular human telomeric G-quadruplex and a sulfonamide derivative of the natural alkaloid Berberine | Descriptor: | 4-[[1-[3-[(17-methoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15,17,19-octaen-16-yl)oxy]propyl]triazol-4-yl]methoxy]benzenesulfonamide, G-guadruplex DNA (23-mer), POTASSIUM ION | Authors: | Bazzicalupi, C, Gratteri, P, Petreni, A, Nocentini, A. | Deposit date: | 2021-09-07 | Release date: | 2022-09-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Complex between monomolecular human telomeric G-quadruplex and a sulfonamide derivative of the natural alkaloid Berberine To Be Published
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4DII
| X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of potassium ions | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2012-01-31 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res., 40, 2012
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4DIH
| X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of sodium ions | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2012-01-31 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res., 40, 2012
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4I7Y
| Crystal Structure of Human Alpha Thrombin in Complex with a 27-mer Aptamer Bound to Exosite II | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, DNA (27-MER), ... | Authors: | Pica, A, Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2012-12-01 | Release date: | 2013-10-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Duplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer. Acta Crystallogr.,Sect.D, 69, 2013
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4L0A
| X-ray structure of an all LNA quadruplex | Descriptor: | DNA/RNA (5'-R(*(TLN)P*(LCG)P*(LCG)P*(LCG)P*(TLN))-3'), GLYCEROL, POTASSIUM ION | Authors: | Russo Krauss, I, Parkinson, G, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2013-05-31 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A regular thymine tetrad and a peculiar supramolecular assembly in the first crystal structure of an all-LNA G-quadruplex. Acta Crystallogr.,Sect.D, 70, 2014
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6SAQ
| wild-type NuoEF from Aquifex aeolicus bound to NADH-OH | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Gerhardt, S. | Deposit date: | 2019-07-17 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural Basis for Inhibition of ROS-Producing Respiratory Complex I by NADH-OH. Angew.Chem.Int.Ed.Engl., 2021
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3QLP
| X-ray structure of the complex between human alpha thrombin and a modified thrombin binding aptamer (mTBA) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ... | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2011-02-03 | Release date: | 2011-10-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Thrombin-aptamer recognition: a revealed ambiguity. Nucleic Acids Res., 39, 2011
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2JT7
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