Author results

5AAW
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STRUCTURE OF A REDESIGNED CROSS-REACTIVE ANTIBODY TO DENGUE VIRUS WITH INCREASED IN VIVO POTENCY
Descriptor:SCFV513, DENGUE SEROTYPE 4 ENVELOPE PROTEIN DOMAIN 3
Authors:Wong, Y., Robinson, L., Lescar, J., Sasisekharan, R.
Deposit date:2015-07-30
Release date:2015-09-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Structure-Guided Design of an Anti-Dengue Antibody Directed to a Non-Immunodominant Epitope.
Cell(Cambridge,Mass.), 162, 2015
5AAM
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STRUCTURE OF A REDESIGNED CROSS-REACTIVE ANTIBODY TO DENGUE VIRUS WITH INCREASED IN VIVO POTENCY
Descriptor:SCFV513, ENVELOPE PROTEIN
Authors:Wong, Y.H., Robinson, L.N., Lescar, J., Sasisekharan, R.
Deposit date:2015-07-27
Release date:2015-08-05
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure-Guided Design of an Anti-Dengue Antibody Directed to a Non-Immunodominant Epitope.
Cell(Cambridge,Mass.), 162, 2015
4M4K
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CRYSTAL STRUCTURE OF THE DROSPHILA BETA,14GALACTOSYLTRANSFERASE 7 MUTANT D211N COMPLEX WITH MANGANESE, UDP-GAL AND XYLOBIOSE
Descriptor:Beta-4-galactosyltransferase 7, MANGANESE (II) ION, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-08-07
Release date:2013-09-25
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4LW6
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF DROSOPHILA BETA1,4GALACTOSYLTRANSFERASE 7 COMPLEX WITH XYLOBIOSE
Descriptor:Beta-4-galactosyltransferase 7, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
Authors:Qasba, P.K., Ramakrishnan, B.
Deposit date:2013-07-26
Release date:2013-09-25
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4LW3
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CRYSTAL STRUCTURE OF THE DROSOPHILA BETA1,4GALACTOSYLTRANSFERASE7 CATALYTIC DOMAIN D211N SINGLE MUTANT ENZYME COMPLEX WITH MANGANESE AND UDP-GALACTOSE
Descriptor:Beta-4-galactosyltransferase 7, MANGANESE (II) ION, GALACTOSE-URIDINE-5'-DIPHOSPHATE
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-07-26
Release date:2013-09-25
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4L41
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HUMAN LACTOSE SYNTHASE: A 2:1 COMPLEX BETWEEN HUMAN ALPHA-LACTALBUMIN AND HUMAN BETA1,4-GALACTOSYLTRANSFERASE
Descriptor:Alpha-lactalbumin, Beta-1,4-galactosyltransferase 1, CALCIUM ION, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-06-07
Release date:2013-10-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Human Lactose Synthase forms a Novel 1:2 Complex between beta1,4Galactosyltransferase 1 and alpha-Lactalbumin Proteins
To be Published
4KRV
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF BOVINE BETA1,4-GALACTOSYLTRANSFERASE MUTANT M344H-GALT1 COMPLEX WITH 6-SULFO-GLCNAC
Descriptor:Beta-1,4-galactosyltransferase 1, MANGANESE (II) ION, 6-AMINOHEXYL-URIDINE-C1,5'-DIPHOSPHATE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-05-17
Release date:2013-08-28
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Investigations on beta 1,4-galactosyltransferase I using 6-sulfo-GlcNAc as an acceptor sugar substrate.
Glycoconj J, 30, 2013
4IRQ
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN BETA1,4GALACTOSYLTRANSFERASE 7 IN CLOSED CONFORMATION IN COMPLEX WITH MANGANESE AND UDP
Descriptor:Beta-1,4-galactosyltransferase 7, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
Authors:Tsutsui, Y., Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-01-15
Release date:2013-09-25
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of beta-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding.
J.Biol.Chem., 288, 2013
4IRP
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN BETA1,4-GALACTOSYLTRANSFERASE-7 IN OPEN CONFORMATION WITH MANGANSES AND UDP
Descriptor:Beta-1,4-galactosyltransferase 7, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Tsutsui, Y., Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-01-15
Release date:2013-09-25
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4EEO
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,6-GLCNAC-ALPHA-BENZYL
Descriptor:Beta-1,4-galactosyltransferase 1, benzyl 2-(acetylamino)-2-deoxy-alpha-D-glucopyranoside, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EEM
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,6-MAN-ALPHA-METHYL
Descriptor:Beta-1,4-galactosyltransferase 1, O1-METHYL-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EEG
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,6-GAL-BETA
Descriptor:Beta-1,4-galactosyltransferase 1, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EEA
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,6-GAL-BETA1,4-GLC-BETA
Descriptor:Beta-1,4-galactosyltransferase 1, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EE5
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH TRISACCHARIDE FROM LACTO-N-NEOTETRAOSE
Descriptor:Beta-1,4-galactosyltransferase 1, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EE4
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH TETRASACCHARIDE FROM LACTO-N-NEOHEXOSE
Descriptor:Beta-1,4-galactosyltransferase 1, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EE3
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH PENTASACCHARIDE
Descriptor:Beta-1,4-galactosyltransferase 1, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
3LW6
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CRYSTAL STRUCTURE OF DROSOPHILA BETA1,4-GALACTOSYLTRANSFERASE-7
Descriptor:Beta-4-galactosyltransferase 7, URIDINE-5'-DIPHOSPHATE, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2010-02-23
Release date:2010-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of the catalytic domain of Drosophila beta1,4-Galactosyltransferase-7.
J.Biol.Chem., 285, 2010
3EE5
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA1,4-GALACTOSYLTRANSFERASE-I (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,3-GAL-BETA-NAPHTHALENEMETHANOL
Descriptor:Beta-1,4-galactosyltransferase 1, 6-AMINOHEXYL-URIDINE-C1,5'-DIPHOSPHATE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2008-09-04
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Deoxygenated Disaccharide Analogs as Specific Inhibitors of {beta}1-4-Galactosyltransferase 1 and Selectin-mediated Tumor Metastasis
J.Biol.Chem., 284, 2009
396D
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CRYSTAL STRUCTURES OF TWO ISOMOPHOUS A-DNA DECAMERS D(GTACGCGTAC) AND D(GGCCGCGGCC)
Descriptor:DNA (5'-D(*GP*GP*CP*CP*GP*CP*GP*GP*CP*C)-3')
Authors:Ban, C., Sundaralingam, M.
Deposit date:1998-04-29
Release date:1998-05-01
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Two Isomophous A-DNA Decamers d(GTACGCGTAC) and d(GGCCGCGGCC)
To be Published
395D
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CRYSTAL STRUCTURES OF TWO ISOMORPHOUS A-DNA DECAMERS D(GTACGCGTAC) AND D(GGCCGCGGCC)
Descriptor:DNA (5'-D(*GP*TP*AP*CP*GP*CP*GP*TP*AP*C)-3')
Authors:Ban, C., Sundaralingam, M.
Deposit date:1998-04-29
Release date:1998-05-01
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of Two Isomorphous A-DNA Decamers d(GTACGCGTAC) and d(GGCCGCGGCC)
To be Published
394D
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CRYSTAL STRUCTURE OF TWO SELF-COMPLEMENTARY CHIMERIC DECAMERS D(CCGG)R(C)D(GCCGG) AND D(CCGG)R(CG)D(CCGG)
Descriptor:DNA/RNA (5'-D(*CP*CP*GP*GP)-R(*CP*GP)-D(*CP*CP*GP*G)-3')
Authors:Ban, C., Sundaralingam, M.
Deposit date:1998-04-29
Release date:1998-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Two Self-Complementary Chimeric Decamers d(CCGG)r(C)d(GCCGG) and d(CCGG)r(CG)d(CCGG)
To be Published
393D
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CRYSTAL STRUCTURE OF TWO SELF-COMPLEMENTARY CHIMERIC DECAMER D(CCGG)R(C)D(GCCGG) AND D(CCGG)R(CG)D(CCGG)
Descriptor:DNA/RNA (5'-D(*CP*CP*GP*GP)-R(*CP)-D(*GP*CP*CP*GP*G)-3')
Authors:Ban, C., Sundaralingam, M., Ramakrishnan, B.
Deposit date:1998-04-29
Release date:1998-05-01
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Two Self-Complementary Chimeric Decamer d(CCGG)r(C)d(GCCGG) and d(CCGG)r(CG)d(CCGG)
To be Published
327D
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CRYSTAL STRUCTURES OF D(GM5CGM5CGCGCGC)
Descriptor:DNA (5'-D(*GP*(5CM)P*GP*(5CM)P*GP*CP*GP*CP*GP*C)-3')
Authors:Tippin, D.B., Ramakrishnan, B., Sundaralingam, M.
Deposit date:1997-03-17
Release date:1997-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Methylation of the Z-DNA decamer d(GC)5 potentiates the formation of A-DNA: crystal structure of d(Gm5CGm5CGCGCGC).
J.Mol.Biol., 270, 1997
306D
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SIDE-BY-SIDE BINDING OF DISTAMYCIN MOLECULES TO D(ICITACIC)
Descriptor:DNA (5'-D(*IP*CP*IP*TP*AP*CP*IP*C)-3'), DISTAMYCIN A, MAGNESIUM ION
Authors:Chen, X., Ramakrishnan, B., Sundaralingam, M.
Deposit date:1997-01-03
Release date:1997-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of the side-by-side binding of distamycin to AT-containing DNA octamers d(ICITACIC) and d(ICATATIC).
J.Mol.Biol., 267, 1997
305D
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SIDE-BY-SIDE BINDING OF DISTAMYCIN MOLECULES TO D(ICATATIC) IN THE TETRAGONAL FORM
Descriptor:DNA (5'-D(*IP*CP*AP*TP*AP*TP*IP*C)-3'), DISTAMYCIN A, MAGNESIUM ION
Authors:Chen, X., Ramakrishnan, B., Sundaralingam, M.
Deposit date:1997-01-03
Release date:1997-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Crystal structures of the side-by-side binding of distamycin to AT-containing DNA octamers d(ICITACIC) and d(ICATATIC).
J.Mol.Biol., 267, 1997
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