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Renin in complex with (S)-1-(3-fluoro-5-(((S)-1-phenylethyl)carbamoyl)benzyl)-4-isopropyl-4-methyl-6-oxotetrahydropyrimidin-2(1H)-iminium
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 3-{[(4S)-2-amino-4-methyl-6-oxo-4-(propan-2-yl)-5,6-dihydropyrimidin-1(4H)-yl]methyl}-5-fluoro-N-[(1S)-1-phenylethyl]benzamide, Renin
Authors:	Orth, P.
Deposit date:	2015-01-13
Release date:	2015-02-25
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Iminopyrimidinones: A novel pharmacophore for the development of orally active renin inhibitors. Bioorg.Med.Chem.Lett., 25, 2015

Renin in complex with (4S)-4-isopropyl-4-methyl-6-oxo-1-(3-(2-oxo-4-phenylpyrrolidin-1-yl)benzyl)tetrahydropyrimidin-2(1H)-iminium
Descriptor:	(2Z,6S)-2-imino-6-methyl-3-{3-[(4R)-2-oxo-4-phenylpyrrolidin-1-yl]benzyl}-6-(propan-2-yl)tetrahydropyrimidin-4(1H)-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin
Authors:	Orth, P.
Deposit date:	2015-01-29
Release date:	2015-02-18
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors. Bioorg. Med. Chem. Lett., 25, 2015

Renin in complex with (S)-1-(3-(benzylcarbamoyl)benzyl)-4-isopropyl-4-methyl-6-oxotetrahydropyrimidin-2(1H)-iminium
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, N-benzyl-3-{[(2Z,4S)-2-imino-4-methyl-6-oxo-4-(propan-2-yl)tetrahydropyrimidin-1(2H)-yl]methyl}benzamide, Renin
Authors:	Orth, P.
Deposit date:	2015-01-29
Release date:	2015-02-18
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors. Bioorg. Med. Chem. Lett., 25, 2015

Structure of CrgA, a Cell Division Structural and Regulatory Protein from Mycobacterium tuberculosis, in Lipid Bilayers
Descriptor:	Cell division protein CrgA
Authors:	Das, N, Dai, J, Hung, I, Rajagopalan, M, Zhou, H, Cross, T.A.
Deposit date:	2014-03-18
Release date:	2014-12-17
Last modified:	2023-06-14
Method:	SOLID-STATE NMR
Cite:	Structure of CrgA, a cell division structural and regulatory protein from Mycobacterium tuberculosis, in lipid bilayers. Proc.Natl.Acad.Sci.USA, 112, 2015