1EK3
 
 | | KAPPA-4 IMMUNOGLOBULIN VL, REC | | Descriptor: | CALCIUM ION, CHLORIDE ION, KAPPA-4 IMMUNOGLOBULIN LIGHT CHAIN VL | | Authors: | Pokkuluri, P.R, Huang, D.-B, Raffen, R, Stevens, F.J, Schiffer, M. | | Deposit date: | 2000-03-06 | | Release date: | 2001-03-06 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Structure of Amyloidogenic Kappa-4 Immunoglobulin VL, REC
To be Published
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1EEQ
 | | M4L/Y(27D)D/T94H Mutant of LEN | | Descriptor: | KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN) | | Authors: | Pokkuluri, P.R, Raffen, R, Dieckman, L, Boogaard, C, Stevens, F.J, Schiffer, M. | | Deposit date: | 2000-02-01 | | Release date: | 2001-02-01 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Increasing protein stability by polar surface residues: domain-wide consequences of interactions within a loop.
Biophys.J., 82, 2002
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4LVE
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3LVE
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2LVE
 | | RECOMBINANT LEN | | Descriptor: | RLEN | | Authors: | Schiffer, M, Pokkuluri, P.R. | | Deposit date: | 1998-05-13 | | Release date: | 1999-05-18 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A domain flip as a result of a single amino-acid substitution.
Structure, 6, 1998
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1LVE
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1EEU
 | | M4L/Y(27D)D/Q89D/T94H mutant of LEN | | Descriptor: | ISOPROPYL ALCOHOL, KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN) | | Authors: | Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M. | | Deposit date: | 2000-02-03 | | Release date: | 2001-02-03 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions.
Protein Sci., 11, 2002
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1EFQ
 | | Q38D mutant of LEN | | Descriptor: | KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN), URANYL (VI) ION, ZINC ION | | Authors: | Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M. | | Deposit date: | 2000-02-09 | | Release date: | 2001-02-09 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions.
Protein Sci., 11, 2002
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5LVE
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1QAC
 | | CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE | | Descriptor: | IMMUNOGLOBULIN LIGHT CHAIN VARIABLE DOMAIN | | Authors: | Pokkuluri, P.R, Cai, X, Johnson, G, Stevens, F.J, Schiffer, M. | | Deposit date: | 1999-02-25 | | Release date: | 2000-02-23 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface.
Protein Sci., 9, 2000
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