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2X7L
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IMPLICATIONS OF THE HIV-1 REV DIMER STRUCTURE AT 3.2A RESOLUTION FOR MULTIMERIC BINDING TO THE REV RESPONSE ELEMENT
Descriptor:FAB HEAVY CHAIN, FAB LIGHT CHAIN, PROTEIN REV
Authors:DiMattia, M.A., Watts, N.R., Stahl, S.J., Rader, C., Wingfield, P.T., Stuart, D.I., Steven, A.C., Grimes, J.M.
Deposit date:2010-03-01
Release date:2010-03-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Implications of the HIV-1 Rev Dimer Structure at 3. 2 A Resolution for Multimeric Binding to the Rev Response Element.
Proc.Natl.Acad.Sci.USA, 107, 2010
6BA5
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POTENT AND SELECTIVE ANTITUMOR ACTIVITY OF A T-CELL ENGAGING BISPECIFIC ANTIBODY TARGETING A MEMBRANE-PROXIMAL EPITOPE OF ROR1
Descriptor:Variable domain of Light Chain, antibody R11, Variable domain Heavy chain, ...
Authors:Park, H., Rader, C.
Deposit date:2017-10-12
Release date:2018-06-13
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BAN
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POTENT AND SELECTIVE ANTITUMOR ACTIVITY OF A T-CELL ENGAGING BISPECIFIC ANTIBODY TARGETING A MEMBRANE-PROXIMAL EPITOPE OF ROR1
Descriptor:Variable domain of R11 Light Chain, Variable domain R11 Heavy chain, Inactive tyrosine-protein kinase transmembrane receptor ROR1
Authors:Park, H., Rader, C.
Deposit date:2017-10-14
Release date:2018-06-13
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DZR
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CRYSTAL STRUCTURE OF H38C2 K99R MUTATION
Descriptor:h38c2 heavy chain, h38c2 light chain, CITRATE ANION, ...
Authors:Park, H., Rader, C.
Deposit date:2018-07-05
Release date:2019-07-10
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues.
Cell Chem Biol, 26, 2019
6U85
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SITE-SPECIFIC LYSINE ARYLATION AS AN ALTERNATIVE BIOCONJUGATION STRATEGY FOR CHEMICALLY PROGRAMMED ANTIBODIES AND ANTIBODY-DRUG CONJUGATES
Descriptor:Antibody Fab heavy chain, antibody Fab Light chain, GLYCEROL
Authors:Park, H., Rader, C.
Deposit date:2019-09-04
Release date:2019-11-13
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates.
Bioconjug.Chem., 30, 2019