Author results

2AX4
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CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF HUMAN 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULPHATE SYNTHETASE 2
Descriptor:Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2, ADENOSINE-5'-DIPHOSPHATE
Authors:Rabeh, W.M., Nedyalkova, L., Ismail, S., Park, H., Arrowsmith, C., Edwards, A., Sundstrom, M., Weigelt, J., Bochkarev, A., Structural Genomics Consortium (SGC)
Deposit date:2005-09-02
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the kinase domain of PAPSS 2
To be Published
2FV7
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CRYSTAL STRUCTURE OF HUMAN RIBOKINASE
Descriptor:Ribokinase, SODIUM ION, MAGNESIUM ION, ...
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Arrowsmith, C., Edwards, A., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2006-01-30
Release date:2006-02-28
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human ribokinase
to be published
2H16
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STRUCTURE OF HUMAN ADP-RIBOSYLATION FACTOR-LIKE 5 (ARL5)
Descriptor:ADP-ribosylation factor-like protein 5A, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
Authors:Rabeh, W.M., Tempel, W., Yaniw, D., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2006-05-16
Release date:2006-06-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human ADP-ribosylation factor-like 5 (ARL5)
To be Published
2H17
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STRUCTURE OF HUMAN ADP-RIBOSYLATION FACTOR-LIKE 5 (ARL5)
Descriptor:ADP-ribosylation factor-like protein 5A, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
Authors:Rabeh, W.M., Tempel, W., Yaniw, D., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2006-05-16
Release date:2006-06-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of human ADP-ribosylation factor-like 5 (ARL5)
To be Published
2HLZ
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CRYSTAL STRUCTURE OF HUMAN KETOHEXOKINASE
Descriptor:Ketohexokinase, UNKNOWN ATOM OR ION
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2006-07-10
Release date:2006-08-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of human ketohexokinase (CASP Target)
To be Published
2I7Q
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CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE A
Descriptor:Choline kinase alpha, CHLORIDE ION, UNKNOWN ATOM OR ION
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Wasney, G., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2006-08-31
Release date:2006-09-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Human Choline Kinase A
To be Published
2IG7
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CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE B
Descriptor:Choline/ethanolamine kinase, UNKNOWN ATOM OR ION
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Wasney, G., Landry, R., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2006-09-22
Release date:2006-10-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Human Choline Kinase B
To be Published
2NZT
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CRYSTAL STRUCTURE OF HUMAN HEXOKINASE II
Descriptor:Hexokinase-2, ALPHA-D-GLUCOSE, BETA-D-GLUCOSE-6-PHOSPHATE, ...
Authors:Rabeh, W.M., Zhu, H., Nedyalkova, L., Tempel, W., Wasney, G., Landry, R., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2006-11-25
Release date:2006-12-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of human hexokinase II
To be Published
2QNR
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HUMAN SEPTIN 2 IN COMPLEX WITH GDP
Descriptor:Septin-2, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
Authors:Rabeh, W.M., Nedyalkova, L., Tempel, W., Landry, R., Crombet, L., Kozieradzki, I., Senisterra, G., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-07-19
Release date:2007-07-31
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human septin 2 in complex with GDP.
To be Published
4Z9M
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CRYSTAL STRUCTURE OF HUMAN SARCOMERIC MITOCHONDRIAL CREATINE KINASE
Descriptor:Creatine kinase S-type, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2015-04-10
Release date:2015-04-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human sarcomeric mitochondrial creatine kinase
To Be Published
2P0E
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HUMAN NICOTINAMIDE RIBOSIDE KINASE 1 IN COMPLEX WITH TIAZOFURIN
Descriptor:Nicotinamide riboside kinase 1, PHOSPHATE ION, CHLORIDE ION, ...
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Brenner, C., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-02-28
Release date:2007-05-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+).
Plos Biol., 5, 2007
2QSY
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HUMAN NICOTINAMIDE RIBOSIDE KINASE 1 IN COMPLEX WITH ADP
Descriptor:Nicotinamide riboside kinase 1, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Brenner, C., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-07-31
Release date:2007-08-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+).
Plos Biol., 5, 2007
2QSZ
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HUMAN NICOTINAMIDE RIBOSIDE KINASE 1 IN COMPLEX WITH NICOTINAMIDE MONONUCLEOTIDE
Descriptor:Nicotinamide riboside kinase 1, PHOSPHATE ION, CHLORIDE ION, ...
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Brenner, C., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-07-31
Release date:2007-08-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+).
Plos Biol., 5, 2007
2QT0
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HUMAN NICOTINAMIDE RIBOSIDE KINASE 1 IN COMPLEX WITH NICOTINAMIDE RIBOSIDE AND AN ATP ANALOGUE
Descriptor:Nicotinamide riboside kinase 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Brenner, C., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-07-31
Release date:2007-08-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+).
Plos Biol., 5, 2007
2QT1
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HUMAN NICOTINAMIDE RIBOSIDE KINASE 1 IN COMPLEX WITH NICOTINAMIDE RIBOSIDE
Descriptor:Nicotinamide riboside kinase 1, PHOSPHATE ION, Nicotinamide riboside, ...
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Brenner, C., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-07-31
Release date:2007-08-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+).
Plos Biol., 5, 2007
2JC3
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STRUCTURE OF O-ACETYLSERINE SULFHYDRYLASE B FROM SALMONELLA TYPHIMURIUM
Descriptor:O-ACETYLSERINE SULFHYDRYLASE B, PYRIDOXAL-5'-PHOSPHATE
Authors:Chattopadhyay, A., Rabeh, W.M., Speroni, F., Meier, M., Ivaninskii, S., Mozzarelli, A., Burkhard, P., Cook, P.F.
Deposit date:2006-12-19
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure, Mechanism, and Conformational Dynamics of O-Acetylserine Sulfhydrylase from Salmonella Typhimurium: Comparison of a and B Isozymes.
Biochemistry, 46, 2007
2Q3F
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X-RAY CRYSTAL STRUCTURE OF PUTATIVE HUMAN RAS-RELATED GTP BINDING D IN COMPLEX WITH GMPPNP
Descriptor:Ras-related GTP-binding protein D, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Mulichak, A.M., Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Keefe, L.J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-05-30
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human Ras-related GTP-binding D.
To be published
3F2R
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CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA IN COMPLEX WITH HEMICHOLINIUM-3
Descriptor:Choline kinase alpha, (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium), UNKNOWN ATOM OR ION
Authors:Hong, B., Tempel, W., Rabeh, W.M., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2008-10-30
Release date:2008-11-11
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of human choline kinase alpha in complex with hemicholinium-3
To be Published
6AAA
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STRUCTURE OF A BLUE-SHIFTED LUCIFERASE FROM AMYDETES VIVIANII
Descriptor:Blue-shifted Luciferase, GLYCEROL
Authors:Carrasco-Lopez, C., Naumov, P., Rabeh, W.
Deposit date:2018-07-18
Release date:2018-08-22
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Beetle luciferases with naturally red- and blue-shifted emission.
Life Sci Alliance, 1, 2018
6ABH
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STRUCTURE OF A NATURAL RED EMITTING LUCIFERASE FROM PHRIXOTHRIX HIRTUS (P1 CRYSTAL FORM)
Descriptor:Red-bioluminescence eliciting luciferase
Authors:Carrasco-Lopez, C., Panjikar, S., Naumov, P., Rabeh, W.
Deposit date:2018-07-21
Release date:2018-08-22
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Beetle luciferases with naturally red- and blue-shifted emission.
Life Sci Alliance, 1, 2018
6AC3
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STRUCTURE OF A NATURAL RED EMITTING LUCIFERASE FROM PHRIXOTHRIX HIRTUS (P3121 CRYSTAL FORM)
Descriptor:Red-bioluminescence eliciting luciferase
Authors:Carrasco-Lopez, C., Panjikar, S., Naumov, P., Rabeh, W.
Deposit date:2018-07-24
Release date:2018-08-22
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Beetle luciferases with naturally red- and blue-shifted emission.
Life Sci Alliance, 1, 2018
2I7N
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CRYSTAL STRUCTURE OF HUMAN PANK1 ALPHA: THE CATALYTIC CORE DOMAIN IN COMPLEX WITH ACCOA
Descriptor:Pantothenate kinase 1, ACETYL COENZYME *A
Authors:Hong, B.S., Wang, L., Tempel, W., Loppnau, P., Allali-Hassani, A., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H.W.
Deposit date:2006-08-31
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.
J.Biol.Chem., 282, 2007
2I7P
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CRYSTAL STRUCTURE OF HUMAN PANK3 IN COMPLEX WITH ACCOA
Descriptor:Pantothenate kinase 3, ACETYL COENZYME *A
Authors:Hong, B.S., Wang, L., Shen, L., Tempel, W., Loppnau, P., Finerty, P., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H.W., Structural Genomics Consortium (SGC)
Deposit date:2006-08-31
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.
J.Biol.Chem., 282, 2007
3EO3
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CRYSTAL STRUCTURE OF THE N-ACETYLMANNOSAMINE KINASE DOMAIN OF HUMAN GNE PROTEIN
Descriptor:Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, ZINC ION, UNKNOWN ATOM OR ION
Authors:Nedyalkova, L., Tong, Y., Rabeh, W.M., Hong, B., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2008-09-26
Release date:2008-10-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal structure of the N-acetylmannosamine kinase domain of GNE.
Plos One, 4, 2009
3FEG
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CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE BETA IN COMPLEX WITH PHOSPHORYLATED HEMICHOLINIUM-3 AND ADENOSINE NUCLEOTIDE
Descriptor:Choline/ethanolamine kinase, (2S)-2-[4'-({dimethyl[2-(phosphonooxy)ethyl]ammonio}acetyl)biphenyl-4-yl]-2-hydroxy-4,4-dimethylmorpholin-4-ium, SULFATE ION, ...
Authors:Hong, B.S., Tempel, W., Rabeh, W.M., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H.W., Structural Genomics Consortium (SGC)
Deposit date:2008-11-29
Release date:2008-12-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.302 Å)
Cite:Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity.
J.Biol.Chem., 285, 2010
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