Author results

3GJC
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CRYSTAL STRUCTURE OF THE E290S MUTANT OF LEUT WITH BOUND OG
Descriptor:Transporter, SODIUM ION, LEUCINE, ...
Authors:Winther, A.M.L., Quick, M., Javitch, J.A., Nissen, P.
Deposit date:2009-03-08
Release date:2009-04-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation
Proc.Natl.Acad.Sci.USA, 106, 2009
3GJD
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CRYSTAL STRUCTURE OF LEUT WITH BOUND OG
Descriptor:Transporter, SODIUM ION, CHLORIDE ION, ...
Authors:Winther, A.M.L., Quick, M., Javitch, J.A., Nissen, P.
Deposit date:2009-03-08
Release date:2009-04-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation
Proc.Natl.Acad.Sci.USA, 106, 2009
4F11
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR GBR2
Descriptor:Gamma-aminobutyric acid type B receptor subunit 2
Authors:Geng, Y., Xiong, D., Mosyak, L., Malito, D.L., Kniazeff, J., Chen, Y., Burmakina, S., Quick, M., Bush, M., Javitch, J.A., Pin, J.-P., Fan, Q.R.
Deposit date:2012-05-05
Release date:2012-06-06
Last modified:2012-08-15
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2.
Nat.Neurosci., 15, 2012
4F12
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR GBR2
Descriptor:Gamma-aminobutyric acid type B receptor subunit 2, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE
Authors:Geng, Y., Xiong, D., Mosyak, L., Malito, D.L., Kniazeff, J., Chen, Y., Burmakina, S., Quick, M., Bush, M., Javitch, J.A., Pin, J.-P., Fan, Q.R.
Deposit date:2012-05-05
Release date:2012-06-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2.
Nat.Neurosci., 15, 2012
5K5S
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CRYSTAL STRUCTURE OF THE ACTIVE FORM OF HUMAN CALCIUM-SENSING RECEPTOR EXTRACELLULAR DOMAIN
Descriptor:Extracellular calcium-sensing receptor, TRYPTOPHAN, PHOSPHATE ION, ...
Authors:Geng, Y., Mosyak, L., Kurinov, I., Zuo, H., Sturchler, E., Cheng, T.C., Subramanyam, P., Brown, A.P., Brennan, S.C., Mun, H.-C., Bush, M., Chen, Y., Nguyen, T., Cao, B., Chang, D., Quick, M., Conigrave, A., Colecraft, H.M., McDonald, P., Fan, Q.R.
Deposit date:2016-05-23
Release date:2016-08-03
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural mechanism of ligand activation in human calcium-sensing receptor.
Elife, 5, 2016
5K5T
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CRYSTAL STRUCTURE OF THE INACTIVE FORM OF HUMAN CALCIUM-SENSING RECEPTOR EXTRACELLULAR DOMAIN
Descriptor:Extracellular calcium-sensing receptor, CALCIUM ION, SULFATE ION, ...
Authors:Geng, Y., Mosyak, L., Kurinov, I., Zuo, H., Sturchler, E., Cheng, T.C., Subramanyam, P., Brown, A.P., Brennan, S.C., Mun, H.-C., Bush, M., Chen, Y., Nguyen, T., Cao, B., Chang, D., Quick, M., Conigrave, A., Colecraft, H.M., McDonald, P., Fan, Q.R.
Deposit date:2016-05-23
Release date:2016-08-03
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural mechanism of ligand activation in human calcium-sensing receptor.
Elife, 5, 2016
4HMK
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CRYSTAL STRUCTURE OF LEUT-E290S WITH BOUND BR
Descriptor:Transporter, LEUCINE, SODIUM ION, ...
Authors:Kantcheva, A.K., Quick, M., Shi, L., Winther, A.M.L., Stolzenberg, S., Weinstein, H., Javitch, J.A., Nissen, P.
Deposit date:2012-10-18
Release date:2013-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:The chloride binding site of Neurotransmitter Sodium Symporters
Proc.Natl.Acad.Sci.USA, 2013
4HOD
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CRYSTAL STRUCTURE OF LEUT-E290S WITH BOUND CL
Descriptor:Transporter, LEUCINE, SODIUM ION, ...
Authors:Kantcheva, A.K., Quick, M., Shi, L., Winther, A.M.L., Stolzenberg, S., Weinstein, H., Javitch, J.A., Nissen, P.
Deposit date:2012-10-22
Release date:2013-05-08
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The chloride binding site of Neurotransmitter Sodium Symporters
Proc.Natl.Acad.Sci.USA, 2013
4US3
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CRYSTAL STRUCTURE OF THE BACTERIAL NSS MEMBER MHST IN AN OCCLUDED INWARD-FACING STATE
Descriptor:TRANSPORTER, TRYPTOPHAN, SODIUM ION, ...
Authors:Malinauskaite, L., Quick, M., Reinhard, L., Lyons, J.A., Yano, H., Javitch, J.A., Nissen, P.
Deposit date:2014-07-02
Release date:2014-09-24
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:A Mechanism for Intracellular Release of Na+ by Neurotransmitter/Sodium Symporters
Nat.Struct.Mol.Biol., 21, 2014
4US4
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CRYSTAL STRUCTURE OF THE BACTERIAL NSS MEMBER MHST IN AN OCCLUDED INWARD-FACING STATE (LIPIDIC CUBIC PHASE FORM)
Descriptor:TRANSPORTER, TRYPTOPHAN, SODIUM ION, ...
Authors:Malinauskaite, L., Quick, M., Reinhard, L., Lyons, J.A., Yano, H., Javitch, J.A., Nissen, P.
Deposit date:2014-07-02
Release date:2014-09-24
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Mechanism for Intracellular Release of Na+ by Neurotransmitter/Sodium Symporters
Nat.Struct.Mol.Biol., 21, 2014
3K3F
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CRYSTAL STRUCTURE OF THE UREA TRANSPORTER FROM DESULFOVIBRIO VULGARIS
Descriptor:Urea transporter, GOLD ION
Authors:Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2009-10-02
Release date:2009-11-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a bacterial homologue of the kidney urea transporter.
Nature, 462, 2009
3K3G
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CRYSTAL STRUCTURE OF THE UREA TRANSPORTER FROM DESULFOVIBRIO VULGARIS BOUND TO 1,3-DIMETHYLUREA
Descriptor:Urea transporter, GOLD ION, 1,3-dimethylurea
Authors:Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2009-10-02
Release date:2009-11-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a bacterial homologue of the kidney urea transporter.
Nature, 462, 2009
3PJZ
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CRYSTAL STRUCTURE OF THE POTASSIUM TRANSPORTER TRKH FROM VIBRIO PARAHAEMOLYTICUS
Descriptor:Potassium uptake protein TrkH, POTASSIUM ION
Authors:Cao, Y., Jin, X., Huang, H., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2010-11-10
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.506 Å)
Cite:Crystal structure of a potassium ion transporter, TrkH.
Nature, 471, 2011
3QNQ
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CRYSTAL STRUCTURE OF THE TRANSPORTER CHBC, THE IIC COMPONENT FROM THE N,N'-DIACETYLCHITOBIOSE-SPECIFIC PHOSPHOTRANSFERASE SYSTEM
Descriptor:PTS system, cellobiose-specific IIC component, DI(N-ACETYL-D-GLUCOSAMINE), ...
Authors:Cao, Y., Jin, X., Huang, H., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2011-02-08
Release date:2011-04-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.295 Å)
Cite:Crystal structure of a phosphorylation-coupled saccharide transporter.
Nature, 473, 2011
4EZC
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CRYSTAL STRUCTURE OF THE UT-B UREA TRANSPORTER FROM BOS TAURUS
Descriptor:Urea transporter 1, BETA-D-GLUCOSE, B-OCTYLGLUCOSIDE, ...
Authors:Cao, Y., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2012-05-02
Release date:2012-06-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structure and permeation mechanism of a mammalian urea transporter.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EZD
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CRYSTAL STRUCTURE OF THE UT-B UREA TRANSPORTER FROM BOS TAURUS BOUND TO SELENOUREA
Descriptor:Urea transporter 1, selenourea, BETA-D-GLUCOSE, ...
Authors:Cao, Y., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2012-05-02
Release date:2012-06-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and permeation mechanism of a mammalian urea transporter.
Proc.Natl.Acad.Sci.USA, 109, 2012
4N7W
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CRYSTAL STRUCTURE OF THE SODIUM BILE ACID SYMPORTER FROM YERSINIA FREDERIKSENII
Descriptor:Transporter, sodium/bile acid symporter family, CITRIC ACID, ...
Authors:Zhou, X., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2013-10-16
Release date:2013-12-11
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Structural basis of the alternating-access mechanism in a bile acid transporter.
Nature, 505, 2013
4N7X
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THE E254A MUTANT OF THE SODIUM BILE ACID SYMPORTER FROM YERSINIA FREDERIKSENII
Descriptor:Transporter, sodium/bile acid symporter family
Authors:Zhou, X., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2013-10-16
Release date:2013-12-11
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of the alternating-access mechanism in a bile acid transporter.
Nature, 505, 2013
5IWS
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CRYSTAL STRUCTURE OF THE TRANSPORTER MALT, THE EIIC DOMAIN FROM THE MALTOSE-SPECIFIC PHOSPHOTRANSFERASE SYSTEM
Descriptor:Protein-N(Pi)-phosphohistidine-sugar phosphotransferase (Enzyme II of the phosphotransferase system) (PTS system glucose-specific IIBC component), MALTOSE
Authors:McCoy, J.G., Ren, Z., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-03-22
Release date:2016-05-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:The Structure of a Sugar Transporter of the Glucose EIIC Superfamily Provides Insight into the Elevator Mechanism of Membrane Transport.
Structure, 24, 2016
6D79
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STRUCTURE OF CYSZ, A SULFATE PERMEASE FROM PSEUDOMONAS FRAGI
Descriptor:Sulfate transporter CysZ
Authors:Sanghai, Z.A., Liu, Q., Clarke, O.B., Banerjee, S., Rajashankar, K.R., Hendrickson, W.A., Mancia, F.
Deposit date:2018-04-24
Release date:2018-05-16
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Structure-based analysis of CysZ-mediated cellular uptake of sulfate.
Elife, 7, 2018
6D9Z
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STRUCTURE OF CYSZ, A SULFATE PERMEASE FROM PSEUDOMONAS DENITRIFICANS
Descriptor:Sulfate transporter CysZ, B-OCTYLGLUCOSIDE
Authors:Sanghai, Z.A., Clarke, O.B., Liu, Q., Banerjee, S., Rajashankar, K.R., Hendrickson, W.A., Mancia, F.
Deposit date:2018-04-30
Release date:2018-05-23
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (3.402132 Å)
Cite:Structure-based analysis of CysZ-mediated cellular uptake of sulfate.
Elife, 7, 2018