Author results

3DPR
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HUMAN RHINOVIRUS 2 BOUND TO A CONCATAMER OF THE VLDL RECEPTOR MODULE V3
Descriptor:Protein VP1, Protein VP2, Protein VP3, ...
Authors:Querol-Audi, J., Pous, J., Fita, I., Verdaguer, N.
Deposit date:2008-07-09
Release date:2009-04-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Minor group human rhinovirus-receptor interactions: geometry of multimodular attachment and basis of recognition
Febs Lett., 583, 2009
3GF5
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CRYSTAL STRUCTURE OF THE P21 R1-R7 N-TERMINAL DOMAIN OF MURINE MVP
Descriptor:Major vault protein, GLYCEROL
Authors:Querol-Audi, J., Casanas, A., Luque, D., Caston, J.R., Fita, I., Verdaguer, N.
Deposit date:2009-02-26
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP
Embo J., 28, 2009
3GNF
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P1 CRYSTAL STRUCTURE OF THE N-TERMINAL R1-R7 OF MURINE MVP
Descriptor:Major vault protein
Authors:Querol-Audi, J., Casanas, A., Uson, I., Luque, D., Caston, J.R., Fita, I., Verdaguer, N.
Deposit date:2009-03-17
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP
Embo J., 28, 2009
3GNG
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P21B CRYSTAL STRUCTURE OF R1-R7 OF MURINE MVP
Descriptor:Major vault protein
Authors:Querol-Audi, J., Casanas, A., Uson, I., Caston, J.R., Fita, I., Verdaguer, N.
Deposit date:2009-03-17
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP
Embo J., 28, 2009
4PDW
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A BENZONITRILE ANALOGUE INHIBITS RHINOVIRUS REPLICATION
Descriptor:Genome polyprotein, Capsid protein VP4/VP2, GLYCEROL, ...
Authors:Querol-Audi, J., Guerra, P., Lacroix, C., Roche, M., Franco, D., Froeyen, M., Terme, T., Vanelle, P., Neyts, J., Leyssen, P., Verdaguer, N.
Deposit date:2014-04-22
Release date:2014-07-02
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:A novel benzonitrile analogue inhibits rhinovirus replication.
J.Antimicrob.Chemother., 69, 2014
5ME5
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CRYSTAL STRUCTURE OF EIF4E FROM C. MELO BOUND TO A EIF4G PEPTIDE
Descriptor:Eukaryotic transcription initiation factor 4E, eIF4G, SULFATE ION
Authors:Querol-Audi, J., Silva, C., Miras, M., Truniger, V., Aranda-Regules, M., Verdaguer, N.
Deposit date:2016-11-14
Release date:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation.
Plant Physiol., 174, 2017
5ME6
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CRYSTAL STRUCTURE OF EIF4E FROM C. MELO BOUND TO A CAP ANALOG
Descriptor:Eukaryotic transcription initiation factor 4E, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Authors:Querol-Audi, J., Silva, C., Miras, M., Aranda-Regules, M., Verdaguer, N.
Deposit date:2016-11-14
Release date:2017-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation.
Plant Physiol., 174, 2017
5ME7
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CRYSTAL STRUCTURE OF EIF4E FROM C. MELO
Descriptor:Eukaryotic transcription initiation factor 4E, GLYCEROL
Authors:Querol-Audi, J., Silva, C., Miras, M., Aranda-Regules, M., Verdaguer, N.
Deposit date:2016-11-14
Release date:2017-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation.
Plant Physiol., 174, 2017
2GSY
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THE 2.6A STRUCTURE OF INFECTIOUS BURSAL VIRUS DERIVED T=1 PARTICLES
Descriptor:polyprotein, CALCIUM ION
Authors:Garriga, D., Querol-Audi, J., Abaitua, F., Saugar, I., Pous, J., Verdaguer, N., Caston, J.R., Rodriguez, J.F.
Deposit date:2006-04-27
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The 2.6-angstrom structure of infectious bursal disease virus-derived t=1 particles reveals new stabilizing elements of the virus capsid.
J.Virol., 80, 2006
2PMP
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STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM THE ISOPRENOID BIOSYNTHETIC PATHWAY OF ARABIDOPSIS THALIANA
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, PHOSPHATE ION, ...
Authors:Calisto, B.M., Perez-Gil, J., Querol-Audi, J., Fita, I., Imperial, S.
Deposit date:2007-04-23
Release date:2007-09-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Biosynthesis of isoprenoids in plants: Structure of the 2C-methyl-D-erithrytol 2,4-cyclodiphosphate synthase from Arabidopsis thaliana. Comparison with the bacterial enzymes.
Protein Sci., 16, 2007
4HL8
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RE-REFINEMENT OF THE VAULT RIBONUCLEOPROTEIN PARTICLE
Descriptor:Major vault protein
Authors:Casanas, A., Querol-Audi, J., Guerra, P., Pous, J., Tanaka, H., Tsukihara, T., Verdaguer, V., Fita, I.
Deposit date:2012-10-16
Release date:2013-06-05
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:New features of vault architecture and dynamics revealed by novel refinement using the deformable elastic network approach.
Acta Crystallogr.,Sect.D, 69, 2013
3B6O
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STRUCTURE OF TREX1 IN COMPLEX WITH A NUCLEOTIDE AND AN INHIBITOR ION (LITHIUM)
Descriptor:Three prime repair exonuclease 1, LITHIUM ION, THYMIDINE-5'-PHOSPHATE
Authors:Brucet, M., Querol-Audi, J., Fita, I., Celada, A.
Deposit date:2007-10-29
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical studies of TREX1 inhibition by metals. Identification of a new active histidine conserved in DEDDh exonucleases.
Protein Sci., 17, 2008
3B6P
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STRUCTURE OF TREX1 IN COMPLEX WITH A NUCLEOTIDE AND INHIBITOR IONS (SODIUM AND ZINC)
Descriptor:Three prime repair exonuclease 1, ZINC ION, SODIUM ION, ...
Authors:Brucet, M., Querol-Audi, J., Fita, I., Celada, A.
Deposit date:2007-10-29
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and biochemical studies of TREX1 inhibition by metals. Identification of a new active histidine conserved in DEDDh exonucleases.
Protein Sci., 17, 2008
4L3B
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X-RAY STRUCTURE OF THE HRV2 A PARTICLE UNCOATING INTERMEDIATE
Descriptor:Protein VP1, Protein VP2, Protein VP3
Authors:Vives-Adrian, L., Querol-Audi, J., Garriga, D., Pous, J., Verdaguer, N.
Deposit date:2013-06-05
Release date:2013-11-27
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle.
Proc.Natl.Acad.Sci.USA, 110, 2013
2PUS
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UNPRECEDENTED ACTIVATION MECHANISM OF A NON-CANONICAL RNA-DEPENDENT RNA POLYMERASE
Descriptor:IBDV VP1 RNA-dependant RNA polymerase
Authors:Garriga, D., Navarro, A., Querol-Audi, J., Abaitua, F., Rodriguez, J.F., Verdaguer, N.
Deposit date:2007-05-09
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QJ1
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CRYSTAL STRUCTURE OF INFECTIOUS BURSAL DISEASE VIRUS VP1 POLYMERASE INCUBATED WITH AN OLIGOPEPTIDE MIMICKING THE VP3 C-TERMINUS
Descriptor:Infectious bursal disease virus VP1 polymerase
Authors:Garriga, D., Navarro, A., Querol-Audi, J., Abaitua, F., Rodriguez, J.F., Verdaguer, N.
Deposit date:2007-07-06
Release date:2007-11-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Unprecedented activation mechanism of a non-canonical RNA-dependent RNA polymerase
To be Published
2R70
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CRYSTAL STRUCTURE OF INFECTIOUS BURSAL DISEASE VIRUS VP1 POLYMERASE, COCRYSTALLIZED WITH AN OLIGOPEPTIDE MIMICKING THE VP3 C-TERMINUS.
Descriptor:INFECTIOUS BURSAL VIRUS VP1 POLYMERASE
Authors:Garriga, D., Navarro, A., Querol-Audi, J., Abaitua, F., Rodriguez, J.F., Verdaguer, N.
Deposit date:2007-09-07
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2R72
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CRYSTAL STRUCTURE OF INFECTIOUS BURSAL DISEASE VIRUS VP1 POLYMERASE, INCUBATED WITH MG2+ ION.
Descriptor:INFECTIOUS BURSAL DISEASE VIRUS VP1 POLYMERASE, MAGNESIUM ION
Authors:Garriga, D., Navarro, A., Querol-Audi, J., Abaitua, F., Rodriguez, J.F., Verdaguer, N.
Deposit date:2007-09-07
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3GPE
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CRYSTAL STRUCTURE ANALYSIS OF PKC (ALPHA)-C2 DOMAIN COMPLEXED WITH CA2+ AND PTDINS(4,5)P2
Descriptor:Protein kinase C alpha type, CALCIUM ION, PHOSPHATE ION, ...
Authors:Ferrer-Orta, C., Querol-Audi, J., Fita, I., Verdaguer, N.
Deposit date:2009-03-23
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.
Proc.Natl.Acad.Sci.USA, 106, 2009
4ZPY
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STRUCTURE OF N170A MVM MUTANT EMPTY CAPSID
Descriptor:VP1 protein
Authors:Guerra, P., Querol-Audi, J., Silva, C., Mateu, M.G., Verdaguer, N.
Deposit date:2015-05-08
Release date:2017-05-24
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis for biologically relevant mechanical stiffening of a virus capsid by cavity-creating or spacefilling mutations.
Sci Rep, 7, 2017
2O4G
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STRUCTURE OF TREX1 IN COMPLEX WITH A NUCLEOTIDE
Descriptor:Three prime repair exonuclease 1, MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE
Authors:Brucet, M., Macias, M.J., Fita, I., Celada, A.
Deposit date:2006-12-04
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains.
J.Biol.Chem., 282, 2007
2O4I
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STRUCTURE OF TREX1 IN COMPLEX WITH DNA
Descriptor:5'-D(*GP*CP*TP*AP*GP*GP*CP*AP*GP*GP*AP*AP*CP*CP*CP*CP*TP*CP*CP*TP*CP*CP*CP*CP*T)-3', Three prime repair exonuclease 1
Authors:Brucet, M., Macias, M.J., Fita, I., Celada, A.
Deposit date:2006-12-04
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains.
J.Biol.Chem., 282, 2007