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8SJ7
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BU of 8sj7 by Molmil
Crystal structure of FBF-2 (RBD+CT) in complex with compact FBE RNA
Descriptor: Fem-3 mRNA-binding factor 2, RNA (5'-R(*CP*UP*GP*UP*GP*AP*AP*UP*G)-3')
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2023-04-17
Release date:2023-09-27
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Competing intrinsically-disordered regions and electrostatic repulsion regulate PUF RNA-binding affinity
To Be Published
6PUN
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BU of 6pun by Molmil
Crystal structure of a ternary complex of FBF-2 with LST-1 (site B) and compact FBE RNA
Descriptor: 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, GLYCEROL, ...
Authors:Qiu, C, Campbell, Z.T, Hall, T.M.T.
Deposit date:2019-07-18
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity.
Elife, 8, 2019
4WZW
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BU of 4wzw by Molmil
Crystal structure of human Puf-A in complex with DNA
Descriptor: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), Pumilio domain-containing protein KIAA0020
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2014-11-20
Release date:2014-12-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9516 Å)
Cite:A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.
Proc.Natl.Acad.Sci.USA, 111, 2014
4WZR
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BU of 4wzr by Molmil
Crystal structure of human Puf-A
Descriptor: GLYCEROL, Pumilio domain-containing protein KIAA0020
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2014-11-20
Release date:2014-12-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.154 Å)
Cite:A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.
Proc.Natl.Acad.Sci.USA, 111, 2014
7S02
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BU of 7s02 by Molmil
Crystal structure of FBF-2 in complex with LST-1 site A peptide and FBE RNA
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FBE RNA, ...
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2021-08-28
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Bipartite interaction sites differentially modulate RNA-binding affinity of a protein complex essential for germline stem cell self-renewal.
Nucleic Acids Res., 50, 2022
7RZZ
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BU of 7rzz by Molmil
Crystal structure of FBF-2 in complex with LST-1 site A peptide and compact FBE RNA
Descriptor: Fem-3 mRNA-binding factor 2, Lateral Signaling Target, RNA
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2021-08-28
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Bipartite interaction sites differentially modulate RNA-binding affinity of a protein complex essential for germline stem cell self-renewal.
Nucleic Acids Res., 50, 2022
6UZ4
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BU of 6uz4 by Molmil
Solution structure of AGL55-Kringle 2 complex
Descriptor: M protein, Plasminogen
Authors:Qiu, C, Yuan, Y, Castellino, F.J.
Deposit date:2019-11-14
Release date:2020-12-09
Method:SOLUTION NMR
Cite:Structural evolution of the A-domain in plasminogen-binding Group A streptococcal M-protein reflects improved adaptability of the pathogen to the host
To Be Published
6UZ5
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BU of 6uz5 by Molmil
Solution structure of KTI55-Kringle 2 complex
Descriptor: M protein, Plasminogen
Authors:Qiu, C, Yuan, Y, Castellino, F.J.
Deposit date:2019-11-14
Release date:2020-12-09
Method:SOLUTION NMR
Cite:Structural evolution of the A-domain in plasminogen-binding Group A streptococcal M-protein reflects improved adaptability of the pathogen to the host
To Be Published
6BZL
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BU of 6bzl by Molmil
Solution structure of VEK75
Descriptor: M protein
Authors:Qiu, C, Yuan, Y, Castellino, F.J.
Deposit date:2017-12-24
Release date:2019-01-16
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization.
J.Struct.Biol., 204, 2018
1XS8
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BU of 1xs8 by Molmil
Solution Structure of YGGX protein of salmonella enterica
Descriptor: UPF0269 protein yggX
Authors:Qiu, C, Thorgersen, M.P, Westler, W.M, Downs, D.M, Markley, J.L.
Deposit date:2004-10-18
Release date:2005-01-04
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution strutcure of Yggx:a protein involved in protection of Fe-S clusters towards oxidation
To be Published
3BCE
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BU of 3bce by Molmil
Crystal structure of the ErbB4 kinase
Descriptor: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, Receptor tyrosine-protein kinase erbB-4, ...
Authors:Qiu, C.
Deposit date:2007-11-12
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase.
Structure, 16, 2008
3BCZ
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BU of 3bcz by Molmil
Crystal structure of Memo
Descriptor: GLYCEROL, Protein MEMO1
Authors:Qiu, C.
Deposit date:2007-11-13
Release date:2007-11-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Memo Is Homologous to Nonheme Iron Dioxygenases and Binds an ErbB2-derived Phosphopeptide in Its Vestigial Active Site.
J.Biol.Chem., 283, 2008
3BBW
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BU of 3bbw by Molmil
crystal structure of the ErbB4 kinase in its inactive conformation
Descriptor: Receptor tyrosine-protein kinase erbB-4
Authors:Qiu, C.
Deposit date:2007-11-11
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4 Å)
Cite:Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase.
Structure, 16, 2008
3BD0
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BU of 3bd0 by Molmil
Crystal structure of Memo, form II
Descriptor: DI(HYDROXYETHYL)ETHER, Protein MEMO1
Authors:Qiu, C.
Deposit date:2007-11-13
Release date:2007-11-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Memo Is Homologous to Nonheme Iron Dioxygenases and Binds an ErbB2-derived Phosphopeptide in Its Vestigial Active Site.
J.Biol.Chem., 283, 2008
3BBT
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BU of 3bbt by Molmil
crystal structure of the ErbB4 kinase in complex with lapatinib
Descriptor: N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE, Receptor tyrosine-protein kinase erbB-4
Authors:Qiu, C.
Deposit date:2007-11-11
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase.
Structure, 16, 2008
3V71
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BU of 3v71 by Molmil
Crystal structure of PUF-6 in complex with 5BE13 RNA
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Puf (Pumilio/fbf) domain-containing protein 7, confirmed by transcript evidence, ...
Authors:Qiu, C, Kershner, A, Wang, Y, Holley, C.H, Wilinski, D, Keles, S, Kimble, J, Wickens, M, Hall, T.M.T.
Deposit date:2011-12-20
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.902 Å)
Cite:Divergence of PUF protein specificity through variations in an RNA-binding pocket
J.Biol.Chem., 2012
3V6Y
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BU of 3v6y by Molmil
crystal structure of FBF-2 in complex with a mutant gld-1 FBEa13 RNA
Descriptor: Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*AP*CP*UP*GP*UP*GP*CP*CP*AP*UP*AP*C)-3')
Authors:Qiu, C, Kershner, A, Wang, Y, Holley, C.H, Wilinski, D, Keles, S, Kimble, J, Wickens, M, Hall, T.M.T.
Deposit date:2011-12-20
Release date:2012-01-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Divergence of PUF protein specificity through variations in an RNA-binding pocket
J.Biol.Chem., 2012
1KHC
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BU of 1khc by Molmil
Crystal Structure of the PWWP Domain of Mammalian DNA Methyltransferase Dnmt3b
Descriptor: DNA cytosine-5 methyltransferase 3B2, UNKNOWN ATOM OR ION
Authors:Qiu, C, Sawada, K, Zhang, X, Cheng, X.
Deposit date:2001-11-29
Release date:2002-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
Nat.Struct.Biol., 9, 2002
6BZJ
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BU of 6bzj by Molmil
Solution structure of AGL55
Descriptor: M protein
Authors:Qiu, C, Yuan, Y, Castellino, F.J.
Deposit date:2017-12-24
Release date:2019-01-16
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization.
J.Struct.Biol., 204, 2018
6NWW
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BU of 6nww by Molmil
Crystal structure of the RRM domain of S. pombe Puf1 in the P212121 space group
Descriptor: CHLORIDE ION, Pumilio domain-containing protein C56F2.08c
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2019-02-07
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity.
Nucleic Acids Res., 47, 2019
6NX5
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BU of 6nx5 by Molmil
Crystal structure of the RRM domain of S. pombe Puf1 in the P21 space group
Descriptor: 1,2-ETHANEDIOL, Pumilio domain-containing protein C56F2.08c
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2019-02-08
Release date:2019-07-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.554 Å)
Cite:Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity.
Nucleic Acids Res., 47, 2019
6NY5
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BU of 6ny5 by Molmil
Crystal structure of the PUM-HD domain of S. pombe Puf1 in complex with RNA
Descriptor: MAGNESIUM ION, Pumilio domain-containing protein C56F2.08c, RNA (5'-R(P*UP*UP*AP*AP*UP*AP*AP*CP*UP*UP*AP*AP*U)-3'), ...
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2019-02-11
Release date:2019-07-03
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity.
Nucleic Acids Res., 47, 2019
5KL1
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BU of 5kl1 by Molmil
Crystal structure of the Pumilio-Nos-hunchback RNA complex
Descriptor: Maternal protein pumilio, Protein nanos, RNA (5'-R(*AP*AP*AP*UP*UP*GP*UP*AP*CP*AP*UP*A)-3'), ...
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2016-06-23
Release date:2016-08-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.701 Å)
Cite:Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.
Elife, 5, 2016
5KL8
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BU of 5kl8 by Molmil
Crystal structure of the Pumilio-Nos-CyclinB RNA complex
Descriptor: Maternal protein pumilio, Protein nanos, RNA (5'-R(*UP*AP*UP*UP*UP*GP*UP*AP*AP*UP*U)-3'), ...
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2016-06-23
Release date:2016-08-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.
Elife, 5, 2016
5KLA
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BU of 5kla by Molmil
Crystal structure of the drosophila Pumilio RNA-binding domain in complex with hunchback RNA
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Maternal protein pumilio, ...
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2016-06-23
Release date:2016-08-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.
Elife, 5, 2016

 

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