Author results

4E26
  • Download 4e26
  • View 4e26
Molmil generated image of 4e26
BRAF IN COMPLEX WITH AN ORGANIC INHIBITOR 7898734
分子名称:Serine/threonine-protein kinase B-raf, 5-chloro-7-[(R)-furan-2-yl(pyridin-2-ylamino)methyl]quinolin-8-ol
著者Qin, J., Xie, P., Ventocilla, C., Zhou, G., Vultur, A., Chen, Q., Herlyn, M., Winkler, J., Marmorstein, R.
登録日2012-03-07
公開日2012-05-09
最終更新日2013-01-09
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Identification of a Novel Family of BRAF(V600E) Inhibitors.
J.Med.Chem., 55, 2012
6MIF
  • Download 6mif
  • View 6mif
Molmil generated image of 6mif
LIM5 DOMAIN OF PINCH1 PROTEIN
分子名称:LIM and senescent cell antigen-like-containing domain protein 1, ZINC ION
著者Qin, J., Vaynberg, J.
登録日2018-09-19
公開日2018-10-31
実験手法SOLUTION NMR
主引用文献Lim5 domain of PINCH1 protein
To Be Published
3UCC
  • Download 3ucc
  • View 3ucc
Molmil generated image of 3ucc
ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-1-PGA/PEP
分子名称:Gamma-enolase, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID, ...
著者Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L.
登録日2011-10-26
公開日2012-08-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
3UCD
  • Download 3ucd
  • View 3ucd
Molmil generated image of 3ucd
ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-2-PGA/PEP
分子名称:Gamma-enolase, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID, ...
著者Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L.
登録日2011-10-26
公開日2012-08-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
3UJE
  • Download 3uje
  • View 3uje
Molmil generated image of 3uje
ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-3-PGA/PEP
分子名称:Gamma-enolase, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID, ...
著者Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L.
登録日2011-11-07
公開日2012-08-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
3UJF
  • Download 3ujf
  • View 3ujf
Molmil generated image of 3ujf
ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-4-PGA/PEP
分子名称:Gamma-enolase, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID, ...
著者Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L.
登録日2011-11-07
公開日2012-08-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
3UJR
  • Download 3ujr
  • View 3ujr
Molmil generated image of 3ujr
ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-5-PGA/PEP
分子名称:Gamma-enolase, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID, ...
著者Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L.
登録日2011-11-08
公開日2012-08-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
3UJS
  • Download 3ujs
  • View 3ujs
Molmil generated image of 3ujs
ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-6-PGA/PEP
分子名称:Gamma-enolase, MAGNESIUM ION, (2R)-3-oxo-2-(phosphonooxy)propanoic acid, ...
著者Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L.
登録日2011-11-08
公開日2012-08-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
2AKM
  • Download 2akm
  • View 2akm
Molmil generated image of 2akm
FLUORIDE INHIBITION OF ENOLASE: CRYSTAL STRUCTURE OF THE INHIBITORY COMPLEX
分子名称:Gamma enolase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Qin, J., Chai, G., Brewer, J.M., Lovelace, L.L.
登録日2005-08-03
公開日2006-03-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Fluoride inhibition of enolase: crystal structure and thermodynamics
Biochemistry, 45, 2006
2AKZ
  • Download 2akz
  • View 2akz
Molmil generated image of 2akz
FLUORIDE INHIBITION OF ENOLASE: CRYSTAL STRUCTURE OF THE INHIBITORY COMPLEX
分子名称:Gamma enolase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Qin, J., Chai, G., Brewer, J.M., Lovelace, L.L.
登録日2005-08-04
公開日2006-03-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Fluoride inhibition of enolase: crystal structure and thermodynamics
Biochemistry, 45, 2006
2EVK
  • Download 2evk
  • View 2evk
Molmil generated image of 2evk
THE STRUCTURES OF THIOLATE- AND CARBOXYLATE-LIGATED FERRIC H93G MYOGLOBIN: MODELS FOR CYTOCHROME P450 AND FOR OXYANION-BOUND HEME PROTEINS
分子名称:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ACETIC ACID
著者Qin, J., Perera, R., Lovelace, L.L., Dawson, J.H., Lebioda, L.
登録日2005-10-31
公開日2006-04-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structures of thiolate- and carboxylate-ligated ferric H93G myoglobin: models for cytochrome P450 and for oxyanion-bound heme proteins.
Biochemistry, 45, 2006
2EVP
  • Download 2evp
  • View 2evp
Molmil generated image of 2evp
THE STRUCTURES OF THIOLATE- AND CARBOXYLATE-LIGATED FERRIC H93G MYOGLOBIN: MODELS FOR CYTOCHROME P450 AND FOR OXYANION-BOUND HEME PROTEINS
分子名称:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, BETA-MERCAPTOETHANOL
著者Qin, J., Perera, R., Lovelace, L.L., Dawson, J.H., Lebioda, L.
登録日2005-10-31
公開日2006-03-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of Thiolate- and Carboxylate-Ligated Ferric H93G Myoglobin: Models for Cytochrome P450 and for Oxyanion-Bound Heme Proteins(,).
Biochemistry, 45, 2006
2KBX
  • Download 2kbx
  • View 2kbx
Molmil generated image of 2kbx
SOLUTION STRUCTURE OF ILK-PINCH COMPLEX
分子名称:Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, ZINC ION
著者Qin, J.
登録日2008-12-10
公開日2008-12-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Cytosketal proteins
To be Published
1CQG
  • Download 1cqg
  • View 1cqg
Molmil generated image of 1cqg
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, 31 STRUCTURES
分子名称:THIOREDOXIN, REF-1 PEPTIDE
著者Clore, G.M., Qin, J., Gronenborn, A.M.
登録日1996-04-02
公開日1996-08-01
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure, 4, 1996
1CQH
  • Download 1cqh
  • View 1cqh
Molmil generated image of 1cqh
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, MINIMIZED AVERAGE STRUCTURE
分子名称:THIOREDOXIN, REF-1 PEPTIDE
著者Clore, G.M., Qin, J., Gronenborn, A.M.
登録日1996-04-02
公開日1996-08-01
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure, 4, 1996
4RLO
  • Download 4rlo
  • View 4rlo
Molmil generated image of 4rlo
HUMAN P70S6K1 WITH RUTHENIUM-BASED INHIBITOR EM5
分子名称:Ribosomal protein S6 kinase beta-1, [(amino-kappaN)methanethiolato](3-fluoro-9-hydroxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dionato-kappa~2~N,N')(1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium, GLYCEROL, ...
著者Domsic, J.F., Barber-Rotenberg, J., Salami, J., Qin, J., Marmorstein, R.
登録日2014-10-17
公開日2015-01-21
実験手法X-RAY DIFFRACTION (2.527 Å)
主引用文献Development of Organometallic S6K1 Inhibitors.
J.Med.Chem., 58, 2015
4RLP
  • Download 4rlp
  • View 4rlp
Molmil generated image of 4rlp
HUMAN P70S6K1 WITH RUTHENIUM-BASED INHIBITOR FL772
分子名称:p70S6K1, [(amino-kappaN)methanethiolato](3-fluoro-9-methoxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dionato-kappa~2~N,N')(N-methyl-1,4,7-trithiecan-9-amine-kappa~3~S~1~,S~4~,S~7~)ruthenium, CHLORIDE ION
著者Domsic, J.F., Barber-Rotenberg, J., Salami, J., Qin, J., Marmorstein, R.
登録日2014-10-17
公開日2015-01-21
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Development of Organometallic S6K1 Inhibitors.
J.Med.Chem., 58, 2015
1MDI
  • Download 1mdi
  • View 1mdi
Molmil generated image of 1mdi
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN MUTANT HUMAN THIOREDOXIN AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB
分子名称:THIOREDOXIN, TARGET SITE IN HUMAN NFKB
著者Clore, G.M., Qin, J., Gronenborn, A.M.
登録日1995-02-27
公開日1995-06-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
1MDJ
  • Download 1mdj
  • View 1mdj
Molmil generated image of 1mdj
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB (RESIDUES 56-68 OF THE P50 SUBUNIT OF NFKB)
分子名称:THIOREDOXIN, TARGET SITE IN HUMAN NFKB
著者Clore, G.M., Qin, J., Gronenborn, A.M.
登録日1995-02-27
公開日1995-06-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
1MDK
  • Download 1mdk
  • View 1mdk
Molmil generated image of 1mdk
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB (RESIDUES 56-68 OF THE P50 SUBUNIT OF NFKB)
分子名称:THIOREDOXIN, TARGET SITE IN HUMAN NFKB
著者Clore, G.M., Qin, J., Gronenborn, A.M.
登録日1995-02-27
公開日1995-06-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
1TRS
  • Download 1trs
  • View 1trs
Molmil generated image of 1trs
THE HIGH-RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURES OF THE OXIDIZED AND REDUCED STATES OF HUMAN THIOREDOXIN
分子名称:THIOREDOXIN
著者Clore, G.M., Qin, J., Gronenborn, A.M.
登録日1994-05-10
公開日1994-09-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure, 2, 1994
1TRU
  • Download 1tru
  • View 1tru
Molmil generated image of 1tru
THE HIGH-RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURES OF THE OXIDIZED AND REDUCED STATES OF HUMAN THIOREDOXIN
分子名称:THIOREDOXIN
著者Clore, G.M., Qin, J., Gronenborn, A.M.
登録日1994-05-10
公開日1994-09-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure, 2, 1994
1TRV
  • Download 1trv
  • View 1trv
Molmil generated image of 1trv
THE HIGH-RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURES OF THE OXIDIZED AND REDUCED STATES OF HUMAN THIOREDOXIN
分子名称:THIOREDOXIN
著者Clore, G.M., Qin, J., Gronenborn, A.M.
登録日1994-05-10
公開日1994-09-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure, 2, 1994
1TRW
  • Download 1trw
  • View 1trw
Molmil generated image of 1trw
THE HIGH-RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURES OF THE OXIDIZED AND REDUCED STATES OF HUMAN THIOREDOXIN
分子名称:THIOREDOXIN
著者Clore, G.M., Qin, J., Gronenborn, A.M.
登録日1994-05-10
公開日1994-09-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure, 2, 1994
5EJC
  • Download 5ejc
  • View 5ejc
Molmil generated image of 5ejc
CRYSTAL STRUCTURAL OF THE TSC1-TBC1D7 COMPLEX
分子名称:TBC1 domain family member 7, Hamartin
著者Wang, Z., Qin, J., Gong, W., Xu, W.
登録日2015-11-01
公開日2016-03-02
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7).
J.Biol.Chem., 291, 2016
<123>