Author results

2I1Q
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RADA RECOMBINASE IN COMPLEX WITH CALCIUM
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, CALCIUM ION, ...
著者Qian, X., He, Y., Ma, X., Fodje, M.N., Grochulski, P., Luo, Y.
登録日2006-08-14
公開日2006-10-24
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Calcium Stiffens Archaeal Rad51 Recombinase from Methanococcus voltae for Homologous Recombination.
J.Biol.Chem., 281, 2006
1P4K
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CRYSTAL STRUCTURE OF THE GLYCOSYLASPARAGINASE PRECURSOR D151N MUTANT
分子名称:N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase, GLYCEROL
著者Qian, X., Guan, C., Guo, H.C.
登録日2003-04-23
公開日2003-05-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A dual role for an aspartic acid in glycosylasparaginase autoproteolysis.
Structure, 11, 2003
1P4V
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CRYSTAL STRUCTURE OF THE GLYCOSYLASPARAGINASE PRECURSOR D151N MUTANT WITH GLYCINE
分子名称:N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase precursor, GLYCINE
著者Qian, X., Guan, C., Guo, H.C.
登録日2003-04-24
公開日2003-05-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A dual role for an aspartic acid in glycosylasparaginase autoproteolysis.
Structure, 11, 2003
1TFI
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A NOVEL ZN FINGER MOTIF IN THE BASAL TRANSCRIPTIONAL MACHINERY: THREE-DIMENSIONAL NMR STUDIES OF THE NUCLEIC-ACID BINDING DOMAIN OF TRANSCRIPTIONAL ELONGATION FACTOR TFIIS
分子名称:TRANSCRIPTIONAL ELONGATION FACTOR SII, ZINC ION
著者Qian, X., Gozani, S., Yoon, H.S., Jeon, C.J., Agarwal, K., Weiss, M.A.
登録日1993-04-27
公開日1993-10-31
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Novel zinc finger motif in the basal transcriptional machinery: three-dimensional NMR studies of the nucleic acid binding domain of transcriptional elongation factor TFIIS.
Biochemistry, 32, 1993
2B21
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RADA RECOMBINASE IN COMPLEX WITH AMPPNP AT PH 6.0
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, POTASSIUM ION, ...
著者Qian, X., He, Y., Wu, Y., Luo, Y.
登録日2005-09-16
公開日2006-08-29
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Methanococcus Voltae Rada at an Acidic pH
To be Published
2F1H
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RECOMBINASE IN COMPLEX WITH AMP-PNP AND POTASSIUM
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, POTASSIUM ION, ...
著者Qian, X., He, Y., Wu, Y., Luo, Y.
登録日2005-11-14
公開日2006-05-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Asp302 determines potassium dependence of a RadA recombinase from Methanococcus voltae.
J.Mol.Biol., 360, 2006
2F1I
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RECOMBINASE IN COMPLEX WITH AMP-PNP
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Qian, X., He, Y., Wu, Y., Luo, Y.
登録日2005-11-14
公開日2006-05-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Asp302 determines potassium dependence of a RadA recombinase from Methanococcus voltae.
J.Mol.Biol., 360, 2006
2F1J
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RECOMBINASE IN COMPLEX WITH ADP
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
著者Qian, X., He, Y., Wu, Y., Luo, Y.
登録日2005-11-14
公開日2006-05-30
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Asp302 determines potassium dependence of a RadA recombinase from Methanococcus voltae.
J.Mol.Biol., 360, 2006
5FSW
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RNA DEPENDENT RNA POLYMERASE QDE-1 FROM THIELAVIA TERRESTRIS
分子名称:RNA DEPENDENT RNA POLYMERASE QDE-1
著者Qian, X., Hamid, F.M., El Sahili, A., Darwis, D.A., Wong, Y.H., Bhushan, S., Makeyev, E.V., Lescar, J.
登録日2016-01-08
公開日2016-03-02
最終更新日2016-05-11
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Functional Evolution in Orthologous Cell-Encoded RNA-Dependent RNA Polymerases
J.Biol.Chem., 291, 2016
2FPK
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RADA RECOMBINASE IN COMPLEX WITH ADP
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, POTASSIUM ION, ...
著者Wu, Y., Qian, X., He, Y., Moya, I.A., Luo, Y.
登録日2006-01-16
公開日2006-01-31
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Methanococcus Voltae Rada in Complex with Adp: hydrolysis-induced conformational change
Biochemistry, 44, 2005
2FPL
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RADA RECOMBINASE IN COMPLEX WITH AMP-PNP AND LOW CONCENTRATION OF K+
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, POTASSIUM ION, ...
著者Wu, Y., Qian, X., He, Y., Moya, I.A., Luo, Y.
登録日2006-01-16
公開日2006-01-31
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Methanococcus Voltae Rada in Complex with Adp: hydrolysis-induced conformational change
Biochemistry, 44, 2005
2FPM
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RADA RECOMBINASE IN COMPLEX WITH AMP-PNP AND HIGH CONCENTRATION OF K+
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, POTASSIUM ION, ...
著者Wu, Y., Qian, X., He, Y., Moya, I.A., Luo, Y.
登録日2006-01-16
公開日2006-01-31
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Methanoccocus Voltae Rada in Complex with Adp: hydrolysis-induced conformational change
Biochemistry, 44, 2005
1KLR
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NMR STRUCTURE OF THE ZFY-6T[Y10F] ZINC FINGER
分子名称:ZINC FINGER Y-CHROMOSOMAL PROTEIN, ZINC ION
著者Lachenmann, M.J., Ladbury, J.E., Phillips, N.B., Narayana, N., Qian, X., Weiss, M.A.
登録日2001-12-12
公開日2002-03-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The hidden thermodynamics of a zinc finger.
J.Mol.Biol., 316, 2002
2XCF
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CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR
分子名称:NS3 PROTEASE, NS4A, ZINC ION, ...
著者Li, X., Zhang, Y.-K., Liu, Y., Ding, C.Z., Li, Q., Zhou, Y., Plattner, J.J., Baker, S.J., Qian, X., Fan, D., Liao, L., Ni, Z.-J., White, G.V., Mordaunt, J.E., Lazarides, L.X., Slater, M.J., Jarvest, R.L., Thommes, P., Ellis, M., Edge, C.M., Hubbard, J.A., Nassau, P., McDowell, B., Skarzynski, T.J., Rowland, P., Somers, D.O., Kazmierski, W.M., Grimes, R.M., Wright, L.L., Smith, G.K., Zou, W., Wright, J., Pennicott, L.E.
登録日2010-04-22
公開日2010-06-02
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease.
Bioorg.Med.Chem.Lett., 20, 2010
2XCN
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CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR
分子名称:NS3 PROTEASE, NS4A, N-[(CYCLOPENTYLOXY)CARBONYL]-3-METHYL-L-VALYL-(4R)-N-{(1R)-3-HYDROXY-1-[HYDROXY(OXIDO)BORANYL]PROPYL}-4-(ISOQUINOLIN-1-YLOXY)-L-PROLINAMIDE, ...
著者Li, X., Zhang, Y.-K., Liu, Y., Ding, C.Z., Li, Q., Zhou, Y., Plattner, J.J., Baker, S.J., Qian, X., Fan, D., Liao, L., Ni, Z.-J., White, G.V., Mordaunt, J.E., Lazarides, L.X., Slater, M.J., Jarvest, R.L., Thommes, P., Ellis, M., Edge, C.M., Hubbard, J.A., Nassau, P., McDowell, B., Skarzynski, T.J., Rowland, P., Somers, D.O., Kazmierski, W.M., Grimes, R.M., Wright, L.L., Smith, G.K., Zou, W., Wright, J., Pennicott, L.E.
登録日2010-04-23
公開日2010-06-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease.
Bioorg.Med.Chem.Lett., 20, 2010
2XNI
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PROTEIN-LIGAND COMPLEX OF A NOVEL MACROCYCLIC HCV NS3 PROTEASE INHIBITOR DERIVED FROM AMINO CYCLIC BORONATES
分子名称:NS3 PROTEASE, NS4A COFACTOR, (1-{[(10-tert-butyl-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19,23,23a-tetradecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosin-7(3H)-yl)carbonyl]amino}-3-hydroxypropyl)(trihydroxy)borate(1-), ...
著者Li, X., Zhang, Y.-K., Liu, Y., Ding, C.Z., Zhou, Y., Li, Q., Plattner, J.J., Baker, S.J., Zhang, S., Kazmierski, W.M., Wright, L.L., Smith, G.K., Grimes, R.M., Crosby, R.M., Creech, K.L., Carballo, L.H., Slater, M.J., Jarvest, R.L., Thommes, P., Hubbard, J.A., Convery, M.A., Nassau, P.M., McDowell, W., Skarzynski, T.J., Qian, X., Fan, D., Liao, L., Ni, Z.-J., Pennicott, L.E., Zou, W., Wright, J.
登録日2010-08-02
公開日2011-08-17
最終更新日2012-09-26
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Novel Macrocyclic Hcv Ns3 Protease Inhibitors Derived from Alpha-Amino Cyclic Boronates.
Bioorg.Med.Chem.Lett., 20, 2010
4DFH
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CRYSTAL STRUCTURE OF CELL ADHESION MOLECULE NECTIN-2/CD112 VARIABLE DOMAIN
分子名称:Poliovirus receptor-related protein 2
著者Liu, J., Qian, X., Chen, Z., Xu, X., Gao, F., Zhang, S., Zhang, R., Qi, J., Gao, G.F., Yan, J.
登録日2012-01-23
公開日2012-06-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
4DFI
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CRYSTAL STRUCTURE OF CELL ADHESION MOLECULE NECTIN-2/CD112 MUTANT FAMP
分子名称:Poliovirus receptor-related protein 2
著者Liu, J., Qian, X., Chen, Z., Xu, X., Gao, F., Zhang, S., Zhang, R., Qi, J., Gao, G.F., Yan, J.
登録日2012-01-23
公開日2012-06-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
2GDJ
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DELTA-62 RADA RECOMBINASE IN COMPLEX WITH AMP-PNP AND MAGNESIUM
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Wu, Y., Qian, X., He, Y., Luo, Y.
登録日2006-03-16
公開日2006-05-16
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Rad51/RadA N-Terminal Domain Activates Nucleoprotein Filament ATPase Activity.
Structure, 14, 2006
1KLS
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NMR STRUCTURE OF THE ZFY-6T[Y10L] ZINC FINGER
分子名称:ZINC FINGER Y-CHROMOSOMAL PROTEIN, ZINC ION
著者Lachenmann, M.J., Ladbury, J.E., Phillips, N.B., Narayana, N., Qian, X., Weiss, M.A.
登録日2001-12-12
公開日2002-03-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The hidden thermodynamics of a zinc finger.
J.Mol.Biol., 316, 2002
1T4G
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ATPASE IN COMPLEX WITH AMP-PNP
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Wu, Y., He, Y., Moya, I.A., Qian, X., Luo, Y.
登録日2004-04-29
公開日2004-08-17
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Archaeal Recombinase RadA; A Snapshot of Its Extended Conformation.
Mol.Cell, 15, 2004
1XRZ
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NMR STRUCTURE OF A ZINC FINGER WITH CYCLOHEXANYLALANINE SUBSTITUTED FOR THE CENTRAL AROMATIC RESIDUE
分子名称:Zinc finger Y-chromosomal protein, ZINC ION
著者Lachenmann, M.J., Ladbury, J.E., Qian, X., Huang, K., Singh, R., Weiss, M.A.
登録日2004-10-17
公開日2004-11-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solvation and the hidden thermodynamics of a zinc finger probed by nonstandard repair of a protein crevice
Protein Sci., 13, 2004
1XU4
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ATPASE IN COMPLEX WITH AMP-PNP, MAGNESIUM AND POTASSIUM CO-F
分子名称:DNA repair and recombination protein radA, MAGNESIUM ION, POTASSIUM ION, ...
著者Wu, Y., Qian, X., He, Y., Moya, I.A., Luo, Y.
登録日2004-10-25
公開日2004-11-16
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of an ATPase-active form of Rad51 homolog from Methanococcus voltae. Insights into potassium dependence
J.Biol.Chem., 280, 2005
2B26
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THE CRYSTAL STRUCTURE OF THE PROTEIN COMPLEX OF YEAST HSP40 SIS1 AND HSP70 SSA1
分子名称:SIS1 protein, Heat shock 70 kDa protein cognate 2
著者Li, J., Wu, Y., Qian, X., Sha, B.
登録日2005-09-16
公開日2006-09-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of yeast Sis1 peptide-binding fragment and Hsp70 Ssa1 C-terminal complex.
Biochem.J., 398, 2006
2K8P
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CHARACTERISATION OF THE STRUCTURAL FEATURES AND INTERACTIONS OF SCLEROSTIN: MOLECULAR INSIGHT INTO A KEY REGULATOR OF WNT-MEDIATED BONE FORMATION
分子名称:Sclerostin
著者Veverka, V., Henry, A.J., Slocombe, P.M., Ventom, A., Mulloy, B., Muskett, F.W., Muzylak, M., Greenslade, K., Moore, A., Zhang, L., Gong, J., Qian, X., Paszty, C., Taylor, R.J., Robinson, M.K., Carr, M.D.
登録日2008-09-18
公開日2009-02-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Characterization of the Structural Features and Interactions of Sclerostin: Molecular insight into a key regulator of Wnt-mediated bone formation
J.Biol.Chem., 284, 2009
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