Author results

1HQI
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COMPONENT P2 FROM THE MULTICOMPONENT PHENOL HYDROXYLASE, NMR, 11 STRUCTURES
Descriptor:PHENOL HYDROXYLASE P2 PROTEIN
Authors:Qian, H., Sethon, I.
Deposit date:1996-09-19
Release date:1996-12-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of phenol hydroxylase protein component P2 determined by NMR spectroscopy.
Biochemistry, 36, 1997
2HQI
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NMR SOLUTION STRUCTURE OF THE OXIDIZED FORM OF MERP, 14 STRUCTURES
Descriptor:MERCURIC TRANSPORT PROTEIN
Authors:Qian, H., Sahlman, L., Eriksson, P.O., Hambreus, C., Edlund, U., Sethson, I.
Deposit date:1998-03-31
Release date:1998-11-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of the oxidized form of MerP, a mercuric ion binding protein involved in bacterial mercuric ion resistance.
Biochemistry, 37, 1998
1JOY
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SOLUTION STRUCTURE OF THE HOMODIMERIC DOMAIN OF ENVZ FROM ESCHERICHIA COLI BY MULTI-DIMENSIONAL NMR.
Descriptor:PROTEIN (ENVZ_ECOLI)
Authors:Tomomori, C., Tanaka, T., Dutta, R., Park, H., Saha, S.K., Zhu, Y., Ishima, R., Liu, D., Tong, K.I., Kurokawa, H., Qian, H., Inouye, M., Ikura, M.
Deposit date:1998-12-28
Release date:2000-01-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ.
Nat.Struct.Biol., 6, 1999
3T5T
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VALL FROM STREPTOMYCES HYGROSCOPICUS IN APO FORM
Descriptor:Putative glycosyltransferase, MAGNESIUM ION, IMIDAZOLE
Authors:Zhang, H., Zheng, L., Qian, H.
Deposit date:2011-07-28
Release date:2012-08-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the substrate specificity of ValL
To be Published
3T7D
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VALL FROM STREPTOMYCES HYGROSCOPICUS IN COMPLEX WITH TREHALOSE
Descriptor:Putative glycosyltransferase, TREHALOSE, MAGNESIUM ION, ...
Authors:Zhang, H., Zheng, L., Qian, H., Chen, J.
Deposit date:2011-07-29
Release date:2012-08-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the substrate specificity of ValL
To be Published
4A3N
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CRYSTAL STRUCTURE OF HMG-BOX OF HUMAN SOX17
Descriptor:TRANSCRIPTION FACTOR SOX-17, ZINC ION
Authors:Gao, N., Gao, H., Qian, H., Si, S., Xie, Y.
Deposit date:2011-10-01
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Human Transcription Factor Sry-Related Box 17 Binding to DNA.
Protein Pept.Lett., 20, 2013
4ILE
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STRUCTURE OF HUMAN ADP-RIBOSYLATION FACTOR-LIKE 8A BINDING TO GDP
Descriptor:ADP-ribosylation factor-like protein 8A, GUANOSINE-5'-DIPHOSPHATE
Authors:Xie, Y., Ren, J., Cheng, Z., Qian, H.
Deposit date:2012-12-31
Release date:2014-01-01
Method:X-RAY DIFFRACTION (2.676 Å)
Cite:Structure of human ADP-ribosylation factor-like 8A binding to GDP
To be Published
5XJY
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CRYO-EM STRUCTURE OF HUMAN ABCA1
Descriptor:ATP-binding cassette sub-family A member 1, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Qian, H.W., Yan, N., Gong, X.
Deposit date:2017-05-04
Release date:2017-06-07
Last modified:2017-07-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the Human Lipid Exporter ABCA1.
Cell, 169, 2017
5XUN
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CRYSTAL STRUCTURE OF Y145F MUTANT OF KACT
Descriptor:Acetyltransferase, ACETYL COENZYME *A, ACETATE ION
Authors:Qian, H.L., Yao, Q.Q., Gan, J.H., Ou, H.Y.
Deposit date:2017-06-23
Release date:2017-07-19
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and characterization of acetyltransferase-type toxin-antitoxin locus in Klebsiella pneumoniae
Mol. Microbiol., 108, 2018
6DS5
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CRYO EM STRUCTURE OF HUMAN SEIPIN
Descriptor:Seipin, N-ACETYL-D-GLUCOSAMINE
Authors:Yan, R.H., Qian, H.W., Yan, N., Yang, H.Y.
Deposit date:2018-06-13
Release date:2018-10-24
Last modified:2018-10-31
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Human SEIPIN Binds Anionic Phospholipids.
Dev. Cell, 47, 2018
5GPD
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CRYSTAL STRUCTURE OF THE BINDING DOMAIN OF SREBP FROM FISSION YEAST
Descriptor:Sterol regulatory element-binding protein 1
Authors:Gong, X., Qian, H.W., Wu, J.P., Yan, N.
Deposit date:2016-08-01
Release date:2016-11-23
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization
Cell Res., 26, 2016
5JNX
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THE 6.6 A CRYO-EM STRUCTURE OF THE FULL-LENGTH HUMAN NPC1 IN COMPLEX WITH THE CLEAVED GLYCOPROTEIN OF EBOLA VIRUS
Descriptor:Niemann-Pick C1 protein, Envelope glycoprotein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gong, X., Qian, H.W., Zhou, X.H., Wu, J.P., Wan, T., Shi, Y., Gao, F., Zhou, Q., Yan, N.
Deposit date:2016-05-01
Release date:2016-06-15
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (6.56 Å)
Cite:Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection
Cell, 165, 2016
6DMB
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CRYO-EM STRUCTURE OF HUMAN PTCH1
Descriptor:Protein patched homolog 1, N-ACETYL-D-GLUCOSAMINE, CHOLESTEROL HEMISUCCINATE
Authors:Yan, N., Gong, X., Qian, H.W.
Deposit date:2018-06-04
Release date:2018-07-11
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6DMO
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CRYO-EM STRUCTURE OF HUMAN PTCH1 WITH THREE MUTATIONS L282Q/T500F/P504L
Descriptor:Protein patched homolog 1, N-ACETYL-D-GLUCOSAMINE
Authors:Yan, N., Gong, X., Qian, H.W.
Deposit date:2018-06-05
Release date:2018-07-11
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6DMY
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CRYO-EM STRUCTURE OF HUMAN PTCH1 AND SHHN COMPLEX
Descriptor:Protein patched homolog 1, Sonic hedgehog protein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Yan, N., Gong, X., Qian, H.W.
Deposit date:2018-06-05
Release date:2018-07-11
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6IGC
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CRYSTAL STRUCTURE OF HPV58/33/52 CHIMERIC L1 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGD
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CRYSTAL STRUCTURE OF HPV58/33 CHIMERIC L1 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGE
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CRYSTAL STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 33 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-12-05
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGF
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CRYSTAL STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 52 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-28
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
4YHC
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CRYSTAL STRUCTURE OF THE WD40 DOMAIN OF SCAP FROM FISSION YEAST
Descriptor:Sterol regulatory element-binding protein cleavage-activating protein, CITRIC ACID
Authors:Gong, X., Li, J.X., Wu, J.P., Yan, C.Y., Yan, N.
Deposit date:2015-02-27
Release date:2015-04-01
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition.
Cell Res., 25, 2015
5C5P
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CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR
Descriptor:Tankyrase-2, ZINC ION, (3R)-3-(1-hydroxy-2-methylpropan-2-yl)-1,3,4,5-tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one, ...
Authors:Lukacs, C.M., Janson, C.A.
Deposit date:2015-06-21
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.
Acs Med.Chem.Lett., 6, 2015
5C5Q
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CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR
Descriptor:Tankyrase-2, ZINC ION, (3R)-10-methyl-3-(propan-2-yl)-1,3,4,5-tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one, ...
Authors:Lukacs, C.M., Janson, C.A.
Deposit date:2015-06-21
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.
Acs Med.Chem.Lett., 6, 2015
5C5R
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CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR
Descriptor:Tankyrase-2, ZINC ION, (7R)-2-hydroxy-7-(propan-2-yl)-7,8-dihydro-5H-pyrano[4,3-b]pyridine-3-carbonitrile, ...
Authors:Lukacs, C.M., Janson, C.A.
Deposit date:2015-06-21
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.
Acs Med.Chem.Lett., 6, 2015