Author results

5GIX
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HUMAN SERUM ALBUMIN-PALMITIC ACID-FE(HN3PIT)CL2
Descriptor:Serum albumin, 14-piperidin-1-yl-11-oxa-13$l^{3}-thia-15,16$l^{4}-diaza-12$l^{3}-ferratetracyclo[8.7.0.0^{2,7}.0^{12,16}]heptadeca-1(10),2(7),3,5,8,13,16-heptaene, PALMITIC ACID
Authors:Yang, F., Qi, J., Wang, T.
Deposit date:2016-06-25
Release date:2017-07-19
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Developing Anticancer Ferric Prodrugs Based on the N-Donor Residues of Human Serum Albumin Carrier IIA Subdomain
J. Med. Chem., 59, 2016
5F1I
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MHC WITH 9-MER PEPTIDE
Descriptor:MHC class I DLA-88, Beta2M, 9-mer peptide
Authors:Liu, J., Chai, Y., QI, J., Gao, G.F.
Deposit date:2015-11-30
Release date:2016-11-30
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
J Immunol., 197, 2016
5F1N
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MHC COMPLEXED TO 11MER PEPTIDE
Descriptor:MHC class I antigen, Beta-2-microglobulin, Peptide from Cytochrome P450 family 1 subfamily B polypeptide 1
Authors:Liu, J., Chai, Y., Qi, J., Gao, G.F.
Deposit date:2015-11-30
Release date:2016-11-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
J Immunol., 197, 2016
5JYY
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STRUCTURE-BASED TETRAVALENT ZANAMIVIR WITH POTENT INHIBITORY ACTIVITY AGAINST DRUG-RESISTANT INFLUENZA VIRUSES
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Fu, L., Wu, Y., Bi, Y., Zhang, S., Lv, X., Qi, J., Li, Y., Lu, X., Yan, J., Gao, G.F., Li, X.
Deposit date:2016-05-15
Release date:2016-06-29
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
3TI3
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CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI4
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CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR OCTANOATE
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI5
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CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH ZANAMIVIR
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI6
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CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH OSELTAMIVIR
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-23
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI8
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CRYSTAL STRUCTURE OF INFLUENZA A VIRUS NEURAMINIDASE N5 COMPLEXED WITH LANINAMIVIR
Descriptor:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TIA
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CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR
Descriptor:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TIB
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CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR OCTANOATE
Descriptor:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TIC
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CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH ZANAMIVIR
Descriptor:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
4G42
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STRUCTURE OF THE CHICKEN MHC CLASS I MOLECULE BF2*0401 COMPLEXED TO PEPITDE P8D
Descriptor:MHC class I alpha chain 2, Beta-2 microglobulin, 8-MERIC PEPTIDE P8D
Authors:Zhang, J., Chen, Y., Qi, J., Gao, F., Liu, J., Kaufman, J., Xia, C., Gao, G.F.
Deposit date:2012-07-16
Release date:2012-11-21
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
4G43
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STRUCTURE OF THE CHICKEN MHC CLASS I MOLECULE BF2*0401 COMPLEXED TO P5E
Descriptor:MHC class I alpha chain 2, Beta-2 microglobulin, 8-MERIC PEPTIDE P5E, ...
Authors:Zhang, J., Chen, Y., Qi, J., Gao, F., Liu, J., Kaufman, J., Xia, C., Gao, G.F.
Deposit date:2012-07-16
Release date:2012-11-21
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
4QY0
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STRUCTURE OF H10 FROM HUMAN-INFECTING H10N8
Descriptor:hemagglutinin, N-ACETYL-D-GLUCOSAMINE
Authors:Wang, M., Zhang, W., Qi, J., Wang, F., Zhou, J., Bi, Y., Wu, Y., Sun, H., Liu, J., Huang, C., Li, X., Yan, J., Shu, Y., Shi, Y., Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY1
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STRUCTURE OF H10 FROM HUMAN-INFECTING H10N8 IN COMPLEX WITH AVIAN RECEPTOR
Descriptor:hemagglutinin, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Wang, M., Zhang, W., Qi, J., Wang, F., Zhou, J., Bi, Y., Wu, Y., Sun, H., Liu, J., Huang, C., Li, X., Yan, J., Shu, Y., Shi, Y., Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY2
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STRUCTURE OF H10 FROM HUMAN-INFECTING H10N8 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOG
Descriptor:hemagglutinin, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID
Authors:Wang, M., Zhang, W., Qi, J., Wang, F., Zhou, J., Bi, Y., Wu, Y., Sun, H., Liu, J., Huang, C., Li, X., Yan, J., Shu, Y., Shi, Y., Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
5GRJ
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CRYSTAL STRUCTURE OF HUMAN PD-L1 WITH MONOCLONAL ANTIBODY AVELUMAB
Descriptor:avelumab H chain, avelumab L chain, Programmed cell death 1 ligand 1
Authors:Liu, K., Tan, S., Chai, Y., Chen, D., Song, H., Zhang, C.W.-H., Shi, Y., Liu, J., Tan, W., Lyu, J., Gao, S., Yan, J., Qi, J., Gao, G.F.
Deposit date:2016-08-11
Release date:2016-11-02
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (3.206 Å)
Cite:Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy.
Cell Res., 27, 2017
5GZN
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
Descriptor:Genome polyprotein, Antibody Heavy chain, Antibody light chain
Authors:Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2016-09-29
Release date:2016-12-28
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5GZO
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
Descriptor:Genome polyprotein, Antibody heavy chain, Antibody light chain
Authors:Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2016-09-29
Release date:2017-01-18
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.755 Å)
Cite:Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
3I6K
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NEWLY IDENTIFIED EPITOPE FROM SARS-COV MEMBRANE PROTEIN COMPLEXED WITH HLA-A*0201
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Liu, J., Sun, Y., Qi, J., Chu, F., Wu, H., Gao, F., Li, T., Yan, J., Gao, G.F.
Deposit date:2009-07-07
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
J Infect Dis, 202, 2010
3MGM
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CRYSTAL STRUCTURE OF HUMAN NUDT16
Descriptor:U8 snoRNA-decapping enzyme
Authors:Yan, J., Lu, G., Zhang, J., Qi, J., Li, Z., Gao, F.
Deposit date:2010-04-07
Release date:2011-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal structure and the template mRNA decapping activity of human NUDT16
To be Published
3MXF
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH THE INHIBITOR JQ1
Descriptor:Bromodomain-containing protein 4, (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, IODIDE ION, ...
Authors:Filippakopoulos, P., Picaud, S., Qi, J., Keates, T., Felletar, I., Fedorov, O., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bradner, J.E., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2010-05-07
Release date:2010-10-06
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Selective inhibition of BET bromodomains.
Nature, 468, 2010
3PWU
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AN IMMMUNODOMINANT CTL EPITOPE FROM RINDERPEST VIRUS PRESENTED BY CATTLE MHC CLASS I MOLECULE N*01801(BOLA-A11)
Descriptor:MHC class I antigen, Beta-2-microglobulin, IPA from Hemagglutinin glycoprotein
Authors:Li, X., Liu, J., Qi, J., Gao, F., Li, Q., Li, X., Zhang, N., Xia, C., Gao, G.F.
Deposit date:2010-12-09
Release date:2011-08-24
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides
J.Virol., 85, 2011
3PWV
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AN IMMMUNODOMINANT CTL EPITOPE FROM RINDERPEST VIRUS PRESENTED BY CATTLE MHC CLASS I MOLECULE N*01801 (BOLA-A11)
Descriptor:MHC class I antigen, Beta-2-microglobulin, 9-mer peptide from Hemagglutinin
Authors:Li, X., Liu, J., Qi, J., Gao, F., Li, Q., Li, X., Zhang, N., Xia, C., Gao, G.F.
Deposit date:2010-12-09
Release date:2011-08-24
Method:X-RAY DIFFRACTION (2.696 Å)
Cite:Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides
J.Virol., 85, 2011