Author results

5GIX
  • Download 5gix
  • View 5gix
Molmil generated image of 5gix
HUMAN SERUM ALBUMIN-PALMITIC ACID-FE(HN3PIT)CL2
Descriptor:Serum albumin, 14-piperidin-1-yl-11-oxa-13$l^{3}-thia-15,16$l^{4}-diaza-12$l^{3}-ferratetracyclo[8.7.0.0^{2,7}.0^{12,16}]heptadeca-1(10),2(7),3,5,8,13,16-heptaene, PALMITIC ACID
Authors:Yang, F., Qi, J., Wang, T.
Deposit date:2016-06-25
Release date:2017-07-19
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Developing Anticancer Ferric Prodrugs Based on the N-Donor Residues of Human Serum Albumin Carrier IIA Subdomain
J. Med. Chem., 59, 2016
5F1I
  • Download 5f1i
  • View 5f1i
Molmil generated image of 5f1i
MHC WITH 9-MER PEPTIDE
Descriptor:MHC class I DLA-88, Beta2M, 9-mer peptide
Authors:Liu, J., Chai, Y., QI, J., Gao, G.F.
Deposit date:2015-11-30
Release date:2016-11-30
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
J Immunol., 197, 2016
5F1N
  • Download 5f1n
  • View 5f1n
Molmil generated image of 5f1n
MHC COMPLEXED TO 11MER PEPTIDE
Descriptor:MHC class I antigen, Beta-2-microglobulin, Peptide from Cytochrome P450 family 1 subfamily B polypeptide 1
Authors:Liu, J., Chai, Y., Qi, J., Gao, G.F.
Deposit date:2015-11-30
Release date:2016-11-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
J Immunol., 197, 2016
5JYY
  • Download 5jyy
  • View 5jyy
Molmil generated image of 5jyy
STRUCTURE-BASED TETRAVALENT ZANAMIVIR WITH POTENT INHIBITORY ACTIVITY AGAINST DRUG-RESISTANT INFLUENZA VIRUSES
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Fu, L., Wu, Y., Bi, Y., Zhang, S., Lv, X., Qi, J., Li, Y., Lu, X., Yan, J., Gao, G.F., Li, X.
Deposit date:2016-05-15
Release date:2016-06-29
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
3I6K
  • Download 3i6k
  • View 3i6k
Molmil generated image of 3i6k
NEWLY IDENTIFIED EPITOPE FROM SARS-COV MEMBRANE PROTEIN COMPLEXED WITH HLA-A*0201
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Liu, J., Sun, Y., Qi, J., Chu, F., Wu, H., Gao, F., Li, T., Yan, J., Gao, G.F.
Deposit date:2009-07-07
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
J Infect Dis, 202, 2010
3MGM
  • Download 3mgm
  • View 3mgm
Molmil generated image of 3mgm
CRYSTAL STRUCTURE OF HUMAN NUDT16
Descriptor:U8 snoRNA-decapping enzyme
Authors:Yan, J., Lu, G., Zhang, J., Qi, J., Li, Z., Gao, F.
Deposit date:2010-04-07
Release date:2011-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal structure and the template mRNA decapping activity of human NUDT16
To be Published
3RE9
  • Download 3re9
  • View 3re9
Molmil generated image of 3re9
CRYSTAL STRUCTURE OF SORTASEC1 FROM STREPTOCOCCUS SUIS
Descriptor:Sortase-like protein
Authors:Lu, G., Qi, J., Gao, F., Yan, J., Tang, J., Gao, G.F.
Deposit date:2011-04-04
Release date:2011-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel "open-form" structure of sortaseC from Streptococcus suis
Proteins, 2011
3RL1
  • Download 3rl1
  • View 3rl1
Molmil generated image of 3rl1
HIV RT DERIVED PEPTIDE COMPLEXED TO HLA-A*0301
Descriptor:HLA class I histocompatibility antigen, A-3 alpha chain, Beta-2-microglobulin, ...
Authors:Zhang, S., Liu, J., Cheng, H., Tan, S., Qi, J., Yan, J., Gao, G.F.
Deposit date:2011-04-19
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
3RL2
  • Download 3rl2
  • View 3rl2
Molmil generated image of 3rl2
HIV NEF DERIVED PEPTIDE NEF73 COMPLEXED TO HLA-A*0301
Descriptor:HLA class I histocompatibility antigen, A-3 alpha chain, Beta-2-microglobulin, ...
Authors:Zhang, S., Liu, J., Cheng, H., Tan, S., Qi, J., Yan, J., Gao, G.F.
Deposit date:2011-04-19
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2.386 Å)
Cite:Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
3S91
  • Download 3s91
  • View 3s91
Molmil generated image of 3s91
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD3 IN COMPLEX WITH THE INHIBITOR JQ1
Descriptor:Bromodomain-containing protein 3, (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, ISOPROPYL ALCOHOL
Authors:Filippakopoulos, P., Picaud, S., Qi, J., Keates, T., Felletar, I., Fedorov, O., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bradner, J.E., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2011-05-31
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal Structure of the first bromodomain of human BRD3 in complex with the inhibitor JQ1
To be Published
3S92
  • Download 3s92
  • View 3s92
Molmil generated image of 3s92
CRYSTAL STRUCTURE OF THE SECOND BROMODOMAIN OF HUMAN BRD3 IN COMPLEX WITH THE INHIBITOR JQ1
Descriptor:Bromodomain-containing protein 3, (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL
Authors:Filippakopoulos, P., Picaud, S., Qi, J., Keates, T., Felletar, I., Fedorov, O., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bradner, J.E., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2011-05-31
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1
To be Published
3TI3
  • Download 3ti3
  • View 3ti3
Molmil generated image of 3ti3
CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI4
  • Download 3ti4
  • View 3ti4
Molmil generated image of 3ti4
CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR OCTANOATE
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI5
  • Download 3ti5
  • View 3ti5
Molmil generated image of 3ti5
CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH ZANAMIVIR
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI6
  • Download 3ti6
  • View 3ti6
Molmil generated image of 3ti6
CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH OSELTAMIVIR
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-23
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI8
  • Download 3ti8
  • View 3ti8
Molmil generated image of 3ti8
CRYSTAL STRUCTURE OF INFLUENZA A VIRUS NEURAMINIDASE N5 COMPLEXED WITH LANINAMIVIR
Descriptor:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TIA
  • Download 3tia
  • View 3tia
Molmil generated image of 3tia
CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR
Descriptor:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TIB
  • Download 3tib
  • View 3tib
Molmil generated image of 3tib
CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR OCTANOATE
Descriptor:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TIC
  • Download 3tic
  • View 3tic
Molmil generated image of 3tic
CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH ZANAMIVIR
Descriptor:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TO2
  • Download 3to2
  • View 3to2
Molmil generated image of 3to2
STRUCTURE OF HLA-A*0201 COMPLEXED WITH PEPTIDE MD3-C9 DERIVED FROM A CLUSTERING REGION OF RESTRICTED CYTOTOXIC T LYMPHOCYTE EPITOPE FROM SARS-COV M PROTEIN
Descriptor:MHC class I antigen, Beta-2-microglobulin, Md3-C9 peptide derived from Membrane glycoprotein
Authors:Liu, J., Qi, J., Gao, F., Yan, J., Gao, G.F.
Deposit date:2011-09-03
Release date:2012-08-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Functional and Structural Definition of a Clustering Region of HLA-A2-restricted Cytotoxic T Lymphocyte Epitopes
Sci.Technology Rev., 29, 2011
3U82
  • Download 3u82
  • View 3u82
Molmil generated image of 3u82
BINDING OF HERPES SIMPLEX VIRUS GLYCOPROTEIN D TO NECTIN-1 EXPLOITS HOST CELL ADHESION
Descriptor:Envelope glycoprotein D, Poliovirus receptor-related protein 1
Authors:Zhang, N., Yan, J., Lu, G., Guo, Z., Fan, Z., Wang, J., Shi, Y., Qi, J., Gao, G.F.
Deposit date:2011-10-15
Release date:2012-03-21
Method:X-RAY DIFFRACTION (3.164 Å)
Cite:Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion.
Nat Commun, 2, 2011
3U83
  • Download 3u83
  • View 3u83
Molmil generated image of 3u83
CRYSTAL STRUCTURE OF NECTIN-1
Descriptor:Poliovirus receptor-related protein 1, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE
Authors:Zhang, N., Yan, J., Lu, G., Guo, Z., Fan, Z., Wang, J., Shi, Y., Qi, J., Gao, G.F.
Deposit date:2011-10-15
Release date:2012-03-21
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion.
Nat Commun, 2, 2011
4DFH
  • Download 4dfh
  • View 4dfh
Molmil generated image of 4dfh
CRYSTAL STRUCTURE OF CELL ADHESION MOLECULE NECTIN-2/CD112 VARIABLE DOMAIN
Descriptor:Poliovirus receptor-related protein 2
Authors:Liu, J., Qian, X., Chen, Z., Xu, X., Gao, F., Zhang, S., Zhang, R., Qi, J., Gao, G.F., Yan, J.
Deposit date:2012-01-23
Release date:2012-06-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
4DFI
  • Download 4dfi
  • View 4dfi
Molmil generated image of 4dfi
CRYSTAL STRUCTURE OF CELL ADHESION MOLECULE NECTIN-2/CD112 MUTANT FAMP
Descriptor:Poliovirus receptor-related protein 2
Authors:Liu, J., Qian, X., Chen, Z., Xu, X., Gao, F., Zhang, S., Zhang, R., Qi, J., Gao, G.F., Yan, J.
Deposit date:2012-01-23
Release date:2012-06-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
4E0R
  • Download 4e0r
  • View 4e0r
Molmil generated image of 4e0r
STRUCTURE OF THE CHICKEN MHC CLASS I MOLECULE BF2*0401
Descriptor:MHC class I alpha chain 2, Beta-2 microglobulin, 8-MERIC PEPTIDE (FUS/TLS)
Authors:Zhang, J., Chen, Y., Qi, J., Gao, F., Kaufman, J., Xia, C., Gao, G.F.
Deposit date:2012-03-05
Release date:2012-11-21
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012