Author results

1LTX
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STRUCTURE OF RAB ESCORT PROTEIN-1 IN COMPLEX WITH RAB GERANYLGERANYL TRANSFERASE AND ISOPRENOID
Descriptor:RAB GERANYLGERANYLTRANSFERASE ALPHA SUBUNIT, RAB GERANYLGERANYLTRANSFERASE BETA SUBUNIT, Rab Escort Protein 1, ...
Authors:Pylypenko, O., Rak, A., Reents, R., Niculae, A., Thoma, N.H., Waldmann, H., Schlichting, I., Goody, R.S., Alexandrov, K.
Deposit date:2002-05-21
Release date:2003-05-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Rab Escort Protein-1 in Complex with Rab Geranylgeranyltransferase
Mol.Cell, 11, 2003
1UED
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CRYSTAL STRUCTURE OF OXYC A CYTOCHROME P450 IMPLICATED IN AN OXIDATIVE C-C COUPLING REACTION DURING VANCOMYCIN BIOSYNTHESIS.
Descriptor:P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, TETRAETHYLENE GLYCOL, ...
Authors:Pylypenko, O., Vitali, F., Zerbe, K., Robinson, J.A., Schlichting, I.
Deposit date:2003-05-11
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of OxyC, a cytochrome P450 implicated in an oxidative C-C coupling reaction during vancomycin biosynthesis
J.Biol.Chem., 278, 2003
2BCG
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STRUCTURE OF DOUBLY PRENYLATED YPT1:GDI COMPLEX
Descriptor:Secretory pathway GDP dissociation inhibitor, GTP-binding protein YPT1, GERAN-8-YL GERAN, ...
Authors:Pylypenko, O., Rak, A., Alexandrov, K.
Deposit date:2005-10-19
Release date:2006-01-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling
Embo J., 25, 2006
2RAI
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THE PX-BAR MEMBRANE REMODELING UNIT OF SORTING NEXIN 9
Descriptor:Sorting nexin-9
Authors:Pylypenko, O., Lundmark, R., Rasmuson, E., Carlsson, S.R., Rak, A.
Deposit date:2007-09-16
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The PX-BAR membrane-remodeling unit of sorting nexin 9
Embo J., 26, 2007
2RAJ
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SO4 BOUND PX-BAR MEMBRANE REMODELING UNIT OF SORTING NEXIN 9
Descriptor:Sorting nexin-9, SULFATE ION
Authors:Pylypenko, O., Lundmark, R., Rasmuson, E., Carlsson, S.R., Rak, A.
Deposit date:2007-09-16
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The PX-BAR membrane-remodeling unit of sorting nexin 9
Embo J., 26, 2007
2RAK
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PI(3)P BOUND PX-BAR MEMBRANE REMODELING UNIT OF SORTING NEXIN 9
Descriptor:Sorting nexin-9, 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE
Authors:Pylypenko, O., Lundmark, R., Rasmuson, E., Carlsson, S.R., Rak, A.
Deposit date:2007-09-16
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The PX-BAR membrane-remodeling unit of sorting nexin 9
Embo J., 26, 2007
3BW6
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CRYSTAL STRUCTURE OF THE LONGIN DOMAIN OF YEAST YKT6
Descriptor:Synaptobrevin homolog YKT6, SULFATE ION
Authors:Pylypenko, O., Schonichen, A., Ludwig, D., Ungermann, C., Goody, R.S., Rak, A., Geyer, M.
Deposit date:2008-01-08
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Farnesylation of the SNARE protein Ykt6 increases its stability and helical folding.
J.Mol.Biol., 377, 2008
3L9I
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MYOSIN VI NUCLEOTIDE-FREE (MDINSERT2) L310G MUTANT CRYSTAL STRUCTURE
Descriptor:Myosin-VI, Calmodulin, TERTIARY-BUTYL ALCOHOL, ...
Authors:Pylypenko, O., Song, L., Sweeney, L.H., Houdusse, A.
Deposit date:2010-01-05
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Role of insert i of myosin VI in modulating nucleotide affinity
To be Published
4LWZ
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CRYSTAL STRUCTURE OF MYO5B GLOBULAR TAIL DOMAIN IN COMPLEX WITH INACTIVE RAB11A
Descriptor:Ras-related protein Rab-11A, Unconventional myosin-Vb, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Pylypenko, O., Attanda, W., Gauquelin, C., Houdusse, A.
Deposit date:2013-07-29
Release date:2013-11-20
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of myosin V Rab GTPase-dependent cargo recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LX0
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CRYSTAL STRUCTURE OF MYO5B GLOBULAR TAIL DOMAIN IN COMPLEX WITH ACTIVE RAB11A
Descriptor:Ras-related protein Rab-11A, Unconventional myosin-Vb, MAGNESIUM ION, ...
Authors:Pylypenko, O., Attanda, W., Gauquelin, C., Houdusse, A.
Deposit date:2013-07-29
Release date:2013-11-20
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis of myosin V Rab GTPase-dependent cargo recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LX1
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CRYSTAL STRUCTURE OF MYO5A GLOBULAR TAIL DOMAIN
Descriptor:Unconventional myosin-Va, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Pylypenko, O., Attanda, W., Coulibaly, D., Gauquelin, C., Houdusse, A.
Deposit date:2013-07-29
Release date:2013-11-20
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural basis of myosin V Rab GTPase-dependent cargo recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LX2
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CRYSTAL STRUCTURE OF MYO5A GLOBULAR TAIL DOMAIN IN COMPLEX WITH MELANOPHILIN GTBD
Descriptor:Unconventional myosin-Va, Melanophilin, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Pylypenko, O., Attanda, W., Gauquelin, C., Houdusse, A.
Deposit date:2013-07-29
Release date:2013-11-20
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of myosin V Rab GTPase-dependent cargo recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
5JCY
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SPIR2-GTBM BOUND TO MYOVA-GTD
Descriptor:Unconventional myosin-Va, Protein spire homolog 2
Authors:Pylypenko, O., Malherbes, G., Welz, T., Kerkhoff, E., Houdusse, A.
Deposit date:2016-04-15
Release date:2016-09-28
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes.
Elife, 5, 2016
5JCZ
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RAB11 BOUND TO MYOVA-GTD
Descriptor:Ras-related protein Rab-11A, Unconventional myosin-Va, MAGNESIUM ION, ...
Authors:Pylypenko, O., Attanda, W., Gauquelin, C., Malherbes, G., Houdusse, A.
Deposit date:2016-04-15
Release date:2016-09-28
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.056 Å)
Cite:Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes.
Elife, 5, 2016
1LFK
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CRYSTAL STRUCTURE OF OXYB, A CYTOCHROME P450 IMPLICATED IN AN OXIDATIVE PHENOL COUPLING REACTION DURING VANCOMYCIN BIOSYNTHESIS
Descriptor:P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pylypenko, O., Zerbe, K., Vitali, F., Zhang, W., Vrijbloed, J.W., Robinson, J.A., Schlichting, I.
Deposit date:2002-04-11
Release date:2002-12-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis.
J.Biol.Chem., 277, 2002
1LG9
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CRYSTAL STRUCTURE OF OXYB, A CYTOCHROME P450 IMPLICATED IN AN OXIDATIVE PHENOL COUPLING REACTION DURING VANCOMYCIN BIOSYNTHESIS
Descriptor:P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pylypenko, O., Zerbe, K., Vitali, F., Zhang, W., Vrijbloed, J.W., Robinson, J.A., Schlichting, I.
Deposit date:2002-04-15
Release date:2002-12-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis.
J.Biol.Chem., 277, 2002
1LGF
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CRYSTAL STRUCTURE OF OXYB, A CYTOCHROME P450 IMPLICATED IN AN OXIDATIVE PHENOL COUPLING REACTION DURING VANCOMYCIN BIOSYNTHESIS
Descriptor:P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pylypenko, O., Zerbe, K., Vitali, F., Zhang, W., Vrijbloed, J.W., Robinson, J.A., Schlichting, I.
Deposit date:2002-04-15
Release date:2002-12-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis.
J.Biol.Chem., 277, 2002
3BN0
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THE RIBOSOMAL PROTEIN S16 FROM AQUIFEX AEOLICUS
Descriptor:30S ribosomal protein S16, GLYCEROL
Authors:Pylypenko, O., Rak, A.
Deposit date:2007-12-13
Release date:2008-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Extreme temperature tolerance of a hyperthermophilic protein coupled to residual structure in the unfolded state
J.Mol.Biol., 379, 2008
4DBP
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MYOSIN VI NUCLEOTIDE-FREE (MDINSERT2) D179Y CRYSTAL STRUCTURE
Descriptor:Myosin-VI, Calmodulin, TERTIARY-BUTYL ALCOHOL, ...
Authors:Pylypenko, O., Sweeney, H.L., Houdusse, A.
Deposit date:2012-01-16
Release date:2013-01-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mutations in myosin VI that cause a loss of coordination between heads provide insights into the structural changes underlying force generation and the importance of gating
To be Published
4DBQ
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MYOSIN VI D179Y (MD-INSERT2-CAM, DELTA-INSERT1) POST-RIGOR STATE
Descriptor:Myosin-VI, Calmodulin, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Pylypenko, O., Sweeney, H.L., Houdusse, A.
Deposit date:2012-01-16
Release date:2013-01-30
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mutations in myosin VI that cause a loss of coordination between heads provide insights into the structural changes underlying force generation and the importance of gating
To be Published
4DBR
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MYOSIN VI D179Y (MD) PRE-POWERSTROKE STATE
Descriptor:Myosin-VI, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Pylypenko, O., Sweeney, H.L., Houdusse, A.
Deposit date:2012-01-16
Release date:2013-01-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mutations in myosin VI that cause a loss of coordination between heads provide insights into the structural changes underlying force generation and the importance of gating
To be Published
3DAD
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CRYSTAL STRUCTURE OF THE N-TERMINAL REGULATORY DOMAINS OF THE FORMIN FHOD1
Descriptor:FH1/FH2 domain-containing protein 1
Authors:Schulte, A., Stolp, B., Schonichen, A., Pylypenko, O., Rak, A., Fackler, O.T., Geyer, M.
Deposit date:2008-05-29
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Human Formin FHOD1 Contains a Bipartite Structure of FH3 and GTPase-Binding Domains Required for Activation.
Structure, 16, 2008
1UKV
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STRUCTURE OF RABGDP-DISSOCIATION INHIBITOR IN COMPLEX WITH PRENYLATED YPT1 GTPASE
Descriptor:Secretory pathway GDP dissociation inhibitor, GTP-binding protein YPT1, MAGNESIUM ION, ...
Authors:Rak, A., Pylypenko, O., Durek, T., Watzke, A., Kushnir, S., Brunsveld, L., Waldmann, H., Goody, R.S., Alexandrov, K.
Deposit date:2003-09-01
Release date:2004-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase
Science, 302, 2003
1VG0
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THE CRYSTAL STRUCTURES OF THE REP-1 PROTEIN IN COMPLEX WITH MONOPRENYLATED RAB7 PROTEIN
Descriptor:Rab proteins geranylgeranyltransferase component A 1, Ras-related protein Rab-7, CHLORIDE ION, ...
Authors:Rak, A., Pylypenko, O., Niculae, A., Pyatkov, K., Goody, R.S., Alexandrov, K.
Deposit date:2004-04-22
Release date:2004-07-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease
Cell(Cambridge,Mass.), 117, 2004
1VG1
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GDP-BOUND RAB7
Descriptor:Ras-related protein Rab-7, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Rak, A., Pylypenko, O., Niculae, A., Pyatkov, K., Goody, R.S., Alexandrov, K.
Deposit date:2004-04-22
Release date:2004-07-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease
Cell(Cambridge,Mass.), 117, 2004
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