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1MNB
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BU of 1mnb by Molmil
BIV TAT PEPTIDE (RESIDUES 68-81), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: BIV TAR RNA, BIV TAT PEPTIDE
Authors:Puglisi, J.D, Chen, L, Blanchard, S, Frankel, A.D.
Deposit date:1996-07-25
Release date:1997-01-27
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a bovine immunodeficiency virus Tat-TAR peptide-RNA complex.
Science, 270, 1995
2M4Q
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BU of 2m4q by Molmil
NMR structure of E. coli ribosomela decoding site with apramycin
Descriptor: APRAMYCIN, RNA (27-MER)
Authors:Puglisi, J.D, Tsai, A, Marshall, R, Viani, E.
Deposit date:2013-02-10
Release date:2013-03-20
Method:SOLUTION NMR
Cite:The impact of aminoglycosides on the dynamics of translation elongation.
Cell Rep, 3, 2013
1I3Y
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BU of 1i3y by Molmil
SOLUTION STRUCTURE OF THE A LOOP OF 23S RIBOSOMAL RNA.
Descriptor: 5'-R(*GP*GP*CP*UP*GP*GP*CP*(OMU)P*GP*UP*UP*CP*GP*CP*CP*AP*GP*CP*C)-3'
Authors:Puglisi, J.D, Blanchard, S.C.
Deposit date:2001-02-17
Release date:2001-04-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the A loop of 23S ribosomal RNA.
Proc.Natl.Acad.Sci.USA, 98, 2001
1BVJ
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BU of 1bvj by Molmil
HIV-1 RNA A-RICH HAIRPIN LOOP
Descriptor: RNA (5'-R(P*GP*GP*CP*GP*AP*CP*GP*GP*UP*GP*UP*AP*AP*AP*AP*AP*UP*CP*UP*CP*GP*CP* C)-3')
Authors:Puglisi, E.V, Puglisi, J.D.
Deposit date:1998-08-31
Release date:1998-12-09
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:HIV-1 A-rich RNA loop mimics the tRNA anticodon structure.
Nat.Struct.Biol., 5, 1998
1VOP
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BU of 1vop by Molmil
CONSERVED RNA COMPONENT OF THE PEPTIDYL TRANSFERASE CENTER, NMR, 33 STRUCTURES
Descriptor: 23S RIBOSOMAL RNA
Authors:Puglisi, E.V, Puglisi, J.D.
Deposit date:1997-08-30
Release date:1997-12-24
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of a conserved RNA component of the peptidyl transferase centre.
Nat.Struct.Biol., 4, 1997
5BR8
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BU of 5br8 by Molmil
Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Sierra, R.G, Gati, C, Laksmono, H, Dao, E.H, Gul, S, Fuller, F, Kern, J, Chatterjee, R, Ibrahim, M, Brewster, A, Young, I.D, Michels-Clark, T, Aquila, A, Mengning, L, Hunter, M.S, Koglin, J.E, Boutet, S, Junco, E.A, Hayes, B, Bogan, M.J, Hampton, C.Y, Puglisi, E.V, Sauter, N.K, Stan, C.A, Zouni, A, Yano, J, Yachandra, V.K, Soltis, S.M, Puglisi, J.D, DeMirci, H.
Deposit date:2015-05-29
Release date:2015-11-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin
To Be Published
4X66
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BU of 4x66 by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Demirci, H, Chen, J, Choi, J, Soltis, M, Puglisi, J.D.
Deposit date:2014-12-06
Release date:2015-11-18
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.446 Å)
Cite:N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics.
Nat.Struct.Mol.Biol., 23, 2016
1BYJ
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BU of 1byj by Molmil
GENTAMICIN C1A A-SITE COMPLEX
Descriptor: 2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose, 3,5-DIAMINO-CYCLOHEXANOL, 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranose, ...
Authors:Yoshizawa, S, Fourmy, D, Puglisi, J.D.
Deposit date:1998-10-16
Release date:1999-10-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural origins of gentamicin antibiotic action.
EMBO J., 17, 1998
8PPL
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BU of 8ppl by Molmil
MERS-CoV Nsp1 bound to the human 43S pre-initiation complex
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N.
Deposit date:2023-07-07
Release date:2023-10-18
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023
8PPK
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BU of 8ppk by Molmil
Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N.
Deposit date:2023-07-07
Release date:2023-10-18
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023
7TQL
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BU of 7tql by Molmil
CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D.
Deposit date:2022-01-26
Release date:2022-04-27
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Nature, 607, 2022
6B19
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BU of 6b19 by Molmil
Architecture of HIV-1 reverse transcriptase initiation complex core
Descriptor: RNA genome fragment, reverse transcriptase p51 subunit, reverse transcriptase p66 subunit, ...
Authors:Larsen, K.P, Mathiharan, Y.K, Chen, D.H, Puglisi, J.D, Skiniotis, G, Puglisi, E.V.
Deposit date:2017-09-18
Release date:2018-04-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Architecture of an HIV-1 reverse transcriptase initiation complex.
Nature, 557, 2018
1A3M
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BU of 1a3m by Molmil
PAROMOMYCIN BINDING INDUCES A LOCAL CONFORMATIONAL CHANGE IN THE A SITE OF 16S RRNA, NMR, 20 STRUCTURES
Descriptor: 16S RRNA (5'-R(*GP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*UP*UP*C)-3'), 16S RRNA (5'-R(*GP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*C)-3')
Authors:Fourmy, D, Yoshizawa, S, Puglisi, J.D.
Deposit date:1998-01-22
Release date:1998-04-29
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA.
J.Mol.Biol., 277, 1998
2JU1
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BU of 2ju1 by Molmil
Solution structure of acyl carrier protein domain from module 2 of 6-deoxyerythronolide B synthase (DEBS)
Descriptor: Erythronolide synthase
Authors:Alekseyev, V.Y, Liu, C.W, Puglisi, J.D, Khosla, C.
Deposit date:2007-08-12
Release date:2007-10-02
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure and proposed domain domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase.
Protein Sci., 16, 2007
2JU2
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BU of 2ju2 by Molmil
Minimized mean solution structure of the acyl carrier protein domain from module 2 of 6-deoxyerythronolide B synthase (DEBS)
Descriptor: Erythronolide synthase
Authors:Alekseyev, V.Y, Liu, C.W, Puglisi, J.D, Khosla, C.
Deposit date:2007-08-12
Release date:2007-10-02
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure and proposed domain domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase.
Protein Sci., 16, 2007
3J4J
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BU of 3j4j by Molmil
Model of full-length T. thermophilus Translation Initiation Factor 2 refined against its cryo-EM density from a 30S Initiation Complex map
Descriptor: Translation initiation factor IF-2
Authors:Simonetti, A, Marzi, S, Billas, I.M.L, Tsai, A, Fabbretti, A, Myasnikov, A, Roblin, P, Vaiana, A.C, Hazemann, I, Eiler, D, Steitz, T.A, Puglisi, J.D, Gualerzi, C.O, Klaholz, B.P.
Deposit date:2013-08-26
Release date:2013-09-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor.
Proc.Natl.Acad.Sci.USA, 110, 2013
3KJ6
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BU of 3kj6 by Molmil
Crystal structure of a Methylated beta2 Adrenergic Receptor-Fab complex
Descriptor: Beta-2 adrenergic receptor, Fab heavy chain, Fab light chain, ...
Authors:Bokoch, M.P, Zou, Y, Rasmussen, S.G.F, Liu, C.W, Nygaard, R, Rosenbaum, D.M, Fung, J.J, Choi, H.-J, Thian, F.S, Kobilka, T.S, Puglisi, J.D, Weis, W.I, Pardo, L, Prosser, S, Mueller, L, Kobilka, B.K.
Deposit date:2009-11-02
Release date:2010-02-16
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature, 463, 2010
4X64
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BU of 4x64 by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Demirci, H, Chen, J, Choi, J, Soltis, M, Puglisi, J.D.
Deposit date:2014-12-06
Release date:2015-11-18
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics.
Nat.Struct.Mol.Biol., 23, 2016
4X62
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BU of 4x62 by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Demirci, H, Chen, J, Choi, J, Soltis, M, Puglisi, J.D.
Deposit date:2014-12-06
Release date:2015-11-18
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.4492 Å)
Cite:N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics.
Nat.Struct.Mol.Biol., 23, 2016
4X65
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BU of 4x65 by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Demirci, H, Chen, J, Choi, J, Soltis, M, Puglisi, J.D.
Deposit date:2014-12-06
Release date:2015-11-18
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.345 Å)
Cite:N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics.
Nat.Struct.Mol.Biol., 23, 2016
5A7U
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BU of 5a7u by Molmil
Single-particle cryo-EM of co-translational folded adr1 domain inside the E. coli ribosome exit tunnel.
Descriptor: REGULATORY PROTEIN ADR1, ZINC ION
Authors:Nilsson, O.B, Hedman, R, Marino, J, Wickles, S, Bischoff, L, Johansson, M, Muller-Lucks, A, Trovato, F, Puglisi, J.D, O'Brien, E, Beckmann, R, von Heijne, G.
Deposit date:2015-07-10
Release date:2015-09-16
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cotranslational Protein Folding Inside the Ribosome Exit Tunnel.
Cell Rep., 12, 2015
6SGC
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BU of 6sgc by Molmil
Rabbit 80S ribosome stalled on a poly(A) tail
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Chandrasekaran, V, Juszkiewicz, S, Choi, J, Puglisi, J.D, Brown, A, Shao, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2019-08-03
Release date:2019-12-04
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of ribosome stalling during translation of a poly(A) tail.
Nat.Struct.Mol.Biol., 26, 2019
1I3X
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BU of 1i3x by Molmil
SOLUTION STRUCTURE OF THE A LOOP OF 23S RIBOSOMAL RNA
Descriptor: 5'-R(*GP*GP*CP*UP*GP*GP*CP*UP*GP*UP*UP*CP*GP*CP*CP*AP*GP*CP*C)-3'
Authors:Blanchard, S.C, Puglisi, J.D.
Deposit date:2001-02-17
Release date:2001-04-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the A loop of 23S ribosomal RNA.
Proc.Natl.Acad.Sci.USA, 98, 2001
1F84
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BU of 1f84 by Molmil
SOLUTION STRUCTURE OF HCV IRES RNA DOMAIN IIID
Descriptor: HCV-1B IRES RNA DOMAIN IIID
Authors:Lukavsky, P.J, Otto, G.A, Lancaster, A.M, Sarnow, P, Puglisi, J.D.
Deposit date:2000-06-28
Release date:2000-11-17
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function.
Nat.Struct.Biol., 7, 2000
1F85
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SOLUTION STRUCTURE OF HCV IRES RNA DOMAIN IIIE
Descriptor: HCV-1B IRES RNA DOMAIN IIIE
Authors:Lukavsky, P.J, Otto, G.A, Lancaster, A.M, Sarnow, P, Puglisi, J.D.
Deposit date:2000-06-28
Release date:2000-11-17
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function.
Nat.Struct.Biol., 7, 2000

 

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