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1VOP
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BU of 1vop by Molmil
CONSERVED RNA COMPONENT OF THE PEPTIDYL TRANSFERASE CENTER, NMR, 33 STRUCTURES
Descriptor: 23S RIBOSOMAL RNA
Authors:Puglisi, E.V, Puglisi, J.D.
Deposit date:1997-08-30
Release date:1997-12-24
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of a conserved RNA component of the peptidyl transferase centre.
Nat.Struct.Biol., 4, 1997
1BVJ
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BU of 1bvj by Molmil
HIV-1 RNA A-RICH HAIRPIN LOOP
Descriptor: RNA (5'-R(P*GP*GP*CP*GP*AP*CP*GP*GP*UP*GP*UP*AP*AP*AP*AP*AP*UP*CP*UP*CP*GP*CP* C)-3')
Authors:Puglisi, E.V, Puglisi, J.D.
Deposit date:1998-08-31
Release date:1998-12-09
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:HIV-1 A-rich RNA loop mimics the tRNA anticodon structure.
Nat.Struct.Biol., 5, 1998
6B19
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BU of 6b19 by Molmil
Architecture of HIV-1 reverse transcriptase initiation complex core
Descriptor: RNA genome fragment, reverse transcriptase p51 subunit, reverse transcriptase p66 subunit, ...
Authors:Larsen, K.P, Mathiharan, Y.K, Chen, D.H, Puglisi, J.D, Skiniotis, G, Puglisi, E.V.
Deposit date:2017-09-18
Release date:2018-04-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Architecture of an HIV-1 reverse transcriptase initiation complex.
Nature, 557, 2018
5BR8
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BU of 5br8 by Molmil
Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Sierra, R.G, Gati, C, Laksmono, H, Dao, E.H, Gul, S, Fuller, F, Kern, J, Chatterjee, R, Ibrahim, M, Brewster, A, Young, I.D, Michels-Clark, T, Aquila, A, Mengning, L, Hunter, M.S, Koglin, J.E, Boutet, S, Junco, E.A, Hayes, B, Bogan, M.J, Hampton, C.Y, Puglisi, E.V, Sauter, N.K, Stan, C.A, Zouni, A, Yano, J, Yachandra, V.K, Soltis, S.M, Puglisi, J.D, DeMirci, H.
Deposit date:2015-05-29
Release date:2015-11-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin
To Be Published
7KJX
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BU of 7kjx by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core with nevirapine
Descriptor: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ...
Authors:Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
Deposit date:2020-10-26
Release date:2021-03-17
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
7KJV
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BU of 7kjv by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core
Descriptor: HIV-1 viral RNA fragment, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ...
Authors:Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
Deposit date:2020-10-26
Release date:2021-03-17
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
7KJW
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BU of 7kjw by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core with efavirenz
Descriptor: (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ...
Authors:Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
Deposit date:2020-10-26
Release date:2021-03-17
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
6WB0
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BU of 6wb0 by Molmil
+3 extended HIV-1 reverse transcriptase initiation complex core (pre-translocation state)
Descriptor: HIV-1 viral RNA genome fragment, Reverse transcriptase/ribonuclease H, reverse transcriptase p51 subunit, ...
Authors:Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Puglisi, E.V.
Deposit date:2020-03-26
Release date:2020-06-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription.
J.Mol.Biol., 432, 2020
6WAZ
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BU of 6waz by Molmil
+1 extended HIV-1 reverse transcriptase initiation complex core (pre-translocation state)
Descriptor: HIV-1 viral RNA genome fragment, Reverse transcriptase p51 subunit, Reverse transcriptase/ribonuclease H, ...
Authors:Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Puglisi, E.V.
Deposit date:2020-03-26
Release date:2020-06-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription.
J.Mol.Biol., 432, 2020
6WB1
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BU of 6wb1 by Molmil
+3 extended HIV-1 reverse transcriptase initiation complex core (intermediate state)
Descriptor: HIV-1 viral RNA genome fragment, REVERSE TRANSCRIPTASE/RIBONUCLEASE H, reverse transcriptase p51 subunit, ...
Authors:Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Chen, D.H, Puglisi, E.V.
Deposit date:2020-03-26
Release date:2020-06-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription.
J.Mol.Biol., 432, 2020
6WB2
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BU of 6wb2 by Molmil
+3 extended HIV-1 reverse transcriptase initiation complex core (displaced state)
Descriptor: HIV-1 viral RNA genome fragment, Reverse transcriptase/ribonuclease H, reverse transcriptase p51 subunit, ...
Authors:Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Chen, D.H, Puglisi, E.V.
Deposit date:2020-03-26
Release date:2020-06-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription.
J.Mol.Biol., 432, 2020
7URI
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BU of 7uri by Molmil
allo-tRNAUTu1A in the A site of the E. coli ribosome
Descriptor: Allo-tRNAUTu1A
Authors:Zhang, J, Prabhakar, A, Krahn, N, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J.
Deposit date:2022-04-22
Release date:2022-08-10
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
7UR5
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BU of 7ur5 by Molmil
allo-tRNAUTu1 in the A, P, and E sites of the E. coli ribosome
Descriptor: allo-tRNAUTu1
Authors:Zhang, J, Krahn, N, Prabhakar, A, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J.
Deposit date:2022-04-21
Release date:2022-08-10
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
7URM
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BU of 7urm by Molmil
allo-tRNAUTu1A in the P site of the E. coli ribosome
Descriptor: allo-tRNAUTU1A
Authors:Zhang, J, Prabhakar, A, Krahn, N, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J.
Deposit date:2022-04-22
Release date:2022-08-10
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
2M4Q
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BU of 2m4q by Molmil
NMR structure of E. coli ribosomela decoding site with apramycin
Descriptor: APRAMYCIN, RNA (27-MER)
Authors:Puglisi, J.D, Tsai, A, Marshall, R, Viani, E.
Deposit date:2013-02-10
Release date:2013-03-20
Method:SOLUTION NMR
Cite:The impact of aminoglycosides on the dynamics of translation elongation.
Cell Rep, 3, 2013

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