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6AZ0
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MITOCHONDRIAL ATPASE PROTEASE YME1
Descriptor:Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1, poly(UNK), ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Puchades, C., Rampello, A.J., Shin, M., Giuliano, C., Wiseman, R.L., Glynn, S.E., Lander, G.C.
Deposit date:2017-09-09
Release date:2017-11-15
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing.
Science, 358, 2017
6NYY
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HUMAN M-AAA PROTEASE AFG3L2, SUBSTRATE-BOUND
Descriptor:AFG3-like protein 2, Substrate, ZINC ION, ...
Authors:Lander, G.C., Puchades, C.
Deposit date:2019-02-12
Release date:2019-05-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Unique Structural Features of the Mitochondrial AAA+ Protease AFG3L2 Reveal the Molecular Basis for Activity in Health and Disease.
Mol.Cell, 75, 2019
6ON2
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LON PROTEASE FROM YERSINIA PESTIS WITH Y2853 SUBSTRATE
Descriptor:ATP-dependent protease La, Bound Y2853 Substrate, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Shin, M., Asmita, A., Puchades, C., Adjei, E., Wiseman, R.L., Karzai, A.W., Lander, G.C.
Deposit date:2019-04-19
Release date:2019-05-01
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for distinct operational modes and protease activation in AAA+ protease Lon.
Sci Adv, 6, 2020
6V11
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LON PROTEASE FROM YERSINIA PESTIS
Descriptor:Lon protease, ADENOSINE-5'-DIPHOSPHATE
Authors:Shin, M., Puchades, C., Asmita, A., Puri, N., Adjei, E., Wiseman, R.L., Karzai, A.W., Lander, G.C.
Deposit date:2019-11-19
Release date:2020-01-22
Last modified:2020-06-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for distinct operational modes and protease activation in AAA+ protease Lon.
Sci Adv, 6, 2020
7KKJ
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STRUCTURE OF ANTI-SARS-COV-2 SPIKE NANOBODY MNB6
Descriptor:Synthetic nanobody mNb6, SULFATE ION, CHLORIDE ION
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKK
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY NB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody Nb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKL
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY MNB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody mNb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KDT
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HUMAN TOM70 IN COMPLEX WITH SARS COV2 ORF9B
Descriptor:Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 2020
5CEX
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CRYSTAL STRUCTURE OF FAB 32H+109L, A PUTATIVE PRECURSOR OF THE PGT121 FAMILY OF POTENT HIV-1 ANTIBODIES
Descriptor:Antibody 9H+3L Fab light chain, Antibody 9H+3L Fab heavy chain, TETRAETHYLENE GLYCOL, ...
Authors:Garces, F., Wilson, I.A.
Deposit date:2015-07-07
Release date:2015-12-23
Last modified:2016-01-06
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CEY
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CRYSTAL STRUCTURE OF FAB 9H+3L, A PUTATIVE PRECURSOR OF THE PGT121 FAMILY OF POTENT HIV-1 ANTIBODIES
Descriptor:Antibody 9H+3L Fab light chain, Antibody 9H+3L Fab heavy chain, GLYCEROL, ...
Authors:Wilson, I.A., Garces, F.
Deposit date:2015-07-07
Release date:2015-12-23
Last modified:2016-01-06
Method:X-RAY DIFFRACTION (2.387 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CEZ
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CRYSTAL STRUCTURE OF THE BG505 SOSIP GP140 HIV-1 ENV TRIMER IN COMPLEX WITH AN EARLY PUTATIVE PRECURSOR OF THE PGT121 FAMILY AT 3.0 ANGSTROM
Descriptor:Envelope glycoprotein gp160, 3H+109L Fab Light Chain, 3H+109L Fab Heavy Chain, ...
Authors:Wilson, I.A., Garces, F.
Deposit date:2015-07-08
Release date:2015-12-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.031 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
171916
PDB entries from 2020-12-02