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5HAM
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BU of 5ham by Molmil
Structure of Rickettsia bellii effector protein RickCE
Descriptor: RickCE
Authors:Pruneda, J.N, Komander, D.
Deposit date:2015-12-30
Release date:2016-07-27
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5HAF
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BU of 5haf by Molmil
Structure of Salmonella enterica effector protein SseL
Descriptor: Deubiquitinase SseL, POTASSIUM ION
Authors:Pruneda, J.N, Komander, D.
Deposit date:2015-12-30
Release date:2016-07-27
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5HAG
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BU of 5hag by Molmil
Structure of Chlamydia trachomatis effector protein ChlaDUB1
Descriptor: Deubiquitinase and deneddylase Dub1, GLYCEROL
Authors:Pruneda, J.N, Komander, D.
Deposit date:2015-12-30
Release date:2016-07-27
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5JP3
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BU of 5jp3 by Molmil
Structure of Xanthomonas campestris effector protein XopD bound to ubiquitin
Descriptor: Polyubiquitin-B, Xanthomonas outer protein D
Authors:Pruneda, J.N, Komander, D.
Deposit date:2016-05-03
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5JP1
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BU of 5jp1 by Molmil
Structure of Xanthomonas campestris effector protein XopD bound to tomato SUMO
Descriptor: (4S,5S)-1,2-DITHIANE-4,5-DIOL, MALONATE ION, Small ubiquitin-related modifier, ...
Authors:Pruneda, J.N, Komander, D.
Deposit date:2016-05-03
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
4BVU
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BU of 4bvu by Molmil
Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate
Descriptor: PROTEIN KINASE OSPG, UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2 D3
Authors:Pruneda, J.N, LeTrong, I, Stenkamp, R.E, Klevit, R.E, Brzovic, P.S.
Deposit date:2013-06-28
Release date:2014-01-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis.
Embo J., 33, 2014
6GZT
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BU of 6gzt by Molmil
Structure of Chlamydia trachomatis effector protein ChlaDUB1 bound to Coenzyme A
Descriptor: COENZYME A, Deubiquitinase and deneddylase Dub1, GLYCEROL, ...
Authors:Pruneda, J.N, Komander, D.
Deposit date:2018-07-05
Release date:2018-11-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
Nat Microbiol, 3, 2018
6GZU
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BU of 6gzu by Molmil
Structure of Chlamydia abortus effector protein ChlaDUB
Descriptor: Conserved membrane protein, GLYCEROL, ZINC ION
Authors:Pruneda, J.N, Komander, D.
Deposit date:2018-07-05
Release date:2018-11-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
Nat Microbiol, 3, 2018
6GZS
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BU of 6gzs by Molmil
Structure of Chlamydia trachomatis effector protein ChlaDUB1 bound to ubiquitin
Descriptor: Deubiquitinase and deneddylase Dub1, GLYCEROL, Polyubiquitin-B, ...
Authors:Pruneda, J.N, Komander, D.
Deposit date:2018-07-05
Release date:2018-11-14
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
Nat Microbiol, 3, 2018
7UYG
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BU of 7uyg by Molmil
Structure of the first OTU domain from Legionella pneumophila effector protein LotA
Descriptor: GLYCEROL, IODIDE ION, LotA
Authors:Pruneda, J.N.
Deposit date:2022-05-06
Release date:2022-12-21
Last modified:2023-01-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA.
Mol.Cell, 83, 2023
5IFR
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BU of 5ifr by Molmil
Structure of the stable UBE2D3-UbDha conjugate
Descriptor: GLYCEROL, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D3
Authors:Pruneda, J.N, Mulder, M.P.C, Witting, K, Ovaa, H, Komander, D.
Deposit date:2016-02-26
Release date:2016-05-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Nat.Chem.Biol., 12, 2016
8ST9
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BU of 8st9 by Molmil
Structure of E3 ligase NleL bound to ubiquitin
Descriptor: E3 ubiquitin-protein ligase SopA, Ubiquitin, prop-2-en-1-amine
Authors:Franklin, T.G, Pruneda, J.N.
Deposit date:2023-05-09
Release date:2023-07-12
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
8ST8
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BU of 8st8 by Molmil
Structure of E3 ligase SopA bound to ubiquitin
Descriptor: E3 ubiquitin-protein ligase SopA, Ubiquitin, prop-2-en-1-amine
Authors:Franklin, T.G, Pruneda, J.N.
Deposit date:2023-05-09
Release date:2023-07-12
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
8ST7
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BU of 8st7 by Molmil
Structure of E3 ligase VsHECT bound to ubiquitin
Descriptor: E3 ubiquitin-protein ligase SopA-like catalytic domain-containing protein, Ubiquitin, prop-2-en-1-amine
Authors:Franklin, T.G, Pruneda, J.N.
Deposit date:2023-05-09
Release date:2023-07-12
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
7UYH
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BU of 7uyh by Molmil
Structure of the first OTU domain from Legionella pneumophila effector protein LotA bound to K6-linked diUb
Descriptor: LotA, Ubiquitin
Authors:Warren, G.D, Pruneda, J.N.
Deposit date:2022-05-06
Release date:2022-12-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA.
Mol.Cell, 83, 2023
5AF5
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BU of 5af5 by Molmil
Structure of Lys33-linked triUb S.G. P 212121
Descriptor: POLYUBIQUITIN-C
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
5OXI
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BU of 5oxi by Molmil
C-terminally retracted ubiquitin L67S mutant
Descriptor: SULFATE ION, Ubiquitin L67S mutant
Authors:Gladkova, C.G, Schubert, A.F, Wagstaff, J.L, Pruneda, J.N, Freund, S.M.V, Komander, D.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.
EMBO J., 36, 2017
3UGB
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BU of 3ugb by Molmil
UbcH5c~Ubiquitin Conjugate
Descriptor: GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3
Authors:Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S.
Deposit date:2011-11-02
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.
Biochemistry, 51, 2012
5AF4
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BU of 5af4 by Molmil
Structure of Lys33-linked diUb
Descriptor: GLYCEROL, SULFATE ION, UBIQUITIN
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
5AF6
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BU of 5af6 by Molmil
Structure of Lys33-linked diUb bound to Trabid NZF1
Descriptor: TRABID, UBIQUITIN, ZINC ION
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
6FFA
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BU of 6ffa by Molmil
FMDV Leader protease bound to substrate ISG15
Descriptor: GLYCEROL, Lbpro, SULFATE ION, ...
Authors:Swatek, K.N, Pruneda, J.N, Komander, D.
Deposit date:2018-01-05
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6W9O
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BU of 6w9o by Molmil
Crystal structure of an OTU deubiquitinase from Wolbachia pipientis wMel
Descriptor: ACETATE ION, OTU domain-containing protein wMelOTU
Authors:Schubert, A.F, Pruneda, J.N, Komander, D.
Deposit date:2020-03-23
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
6W9R
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BU of 6w9r by Molmil
Crystal structure of an OTU deubiquitinase from Wolbachia pipientis wMel bound to ubiquitin
Descriptor: CITRATE ANION, OTU domain-containing protein wMelOTU, Ubiquitin
Authors:Schubert, A.F, Pruneda, J.N, Komander, D.
Deposit date:2020-03-23
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
6W9S
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BU of 6w9s by Molmil
Crystal structure of an OTU deubiquitinase from Escherichia albertii bound to ubiquitin
Descriptor: FORMIC ACID, OTU domain-containing protein EschOTU, Ubiquitin
Authors:Schubert, A.F, Pruneda, J.N, Komander, D.
Deposit date:2020-03-23
Release date:2020-07-01
Last modified:2020-08-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
5OXH
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BU of 5oxh by Molmil
C-terminally retracted ubiquitin T66V/L67N mutant
Descriptor: SULFATE ION, Ubiquitin T66V/L67N mutant
Authors:Gladkova, C, Schubert, A.F, Wagstaff, J.L, Pruneda, J.P, Freund, S.M.V, Komander, D.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.
EMBO J., 36, 2017

 

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