Author results

4I4T
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CRYSTAL STRUCTURE OF TUBULIN-RB3-TTL-ZAMPANOLIDE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Steinmetz, M.O.
Deposit date:2012-11-28
Release date:2013-01-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents.
Science, 339, 2013
1LY2
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CRYSTAL STRUCTURE OF UNLIGANDED HUMAN CD21 SCR1-SCR2 (COMPLEMENT RECEPTOR TYPE 2)
Descriptor:complement receptor type 2, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Prota, A.E., Sage, D.R., Stehle, T., Fingeroth, J.D.
Deposit date:2002-06-06
Release date:2002-07-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of human CD21: Implications for Epstein-Barr virus and C3d binding.
Proc.Natl.Acad.Sci.USA, 99, 2002
1NBQ
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CRYSTAL STRUCTURE OF HUMAN JUNCTIONAL ADHESION MOLECULE TYPE 1
Descriptor:Junctional adhesion molecule 1
Authors:Prota, A.E., Campbell, J.A., Schelling, P., Forrest, J.C., Watson, M.J., Peters, T.R., Aurrand-Lions, M., Imhof, B.A., Dermody, T.S., Stehle, T.
Deposit date:2002-12-03
Release date:2003-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of human junctional adhesion molecule 1: Implications for reovirus binding
Proc.Natl.Acad.Sci.USA, 100, 2003
4I50
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-EPOTHILONE A COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Bargsten, K., Zurwerra, D., Field, J.J., Diaz, J.F., Altmann, K.H., Steinmetz, M.O.
Deposit date:2012-11-28
Release date:2013-01-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents.
Science, 339, 2013
4I55
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Bargsten, K., Zurwerra, D., Field, J.J., Diaz, J.F., Altmann, K.H., Steinmetz, M.O.
Deposit date:2012-11-28
Release date:2013-01-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents.
Science, 339, 2013
4IHJ
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-ADP COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Magiera, M.M., Kuijpers, M., Bargsten, K., Frey, D., Wieser, M., Jaussi, R., Hoogenraad, C.C., Kammerer, R.A., Janke, C., Steinmetz, M.O.
Deposit date:2012-12-18
Release date:2013-02-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of tubulin tyrosination by tubulin tyrosine ligase.
J.Cell Biol., 200, 2013
4IIJ
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-APO COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Magiera, M.M., Kuijpers, M., Bargsten, K., Frey, D., Wieser, M., Jaussi, R., Hoogenraad, C.C., Kammerer, R.A., Janke, C., Steinmetz, M.O.
Deposit date:2012-12-20
Release date:2013-01-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of tubulin tyrosination by tubulin tyrosine ligase.
J.Cell Biol., 200, 2013
4O2A
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TUBULIN-BAL27862 COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Franck, D., Bachmann, F., Bargsten, K., Buey, R.M., Pohlmann, J., Reinelt, S., Lane, H., Steinmetz, M.O.
Deposit date:2013-12-17
Release date:2014-03-05
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization.
J.Mol.Biol., 426, 2014
4O2B
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TUBULIN-COLCHICINE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Franck, D., Bachmann, F., Bargsten, K., Buey, R.M., Pohlmann, J., Reinelt, S., Lane, H., Steinmetz, M.O.
Deposit date:2013-12-17
Release date:2014-03-05
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization.
J.Mol.Biol., 426, 2014
4O4H
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TUBULIN-LAULIMALIDE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Bargsten, K., Northcote, P.T., Marsh, M., Altmann, K.H., Miller, J.H., Diaz, J.F., Steinmetz, M.O.
Deposit date:2013-12-18
Release date:2014-03-05
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of microtubule stabilization by laulimalide and peloruside a.
Angew.Chem.Int.Ed.Engl., 53, 2014
4O4I
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TUBULIN-LAULIMALIDE-EPOTHILONE A COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Bargsten, K., Northcote, P.T., Marsh, M., Altmann, K.H., Miller, J.H., Diaz, J.F., Steinmetz, M.O.
Deposit date:2013-12-18
Release date:2014-03-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of microtubule stabilization by laulimalide and peloruside a.
Angew.Chem.Int.Ed.Engl., 53, 2014
4O4J
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TUBULIN-PELORUSIDE A COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Bargsten, K., Northcote, P.T., Marsh, M., Altmann, K.H., Miller, J.H., Diaz, J.F., Steinmetz, M.O.
Deposit date:2013-12-18
Release date:2014-03-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of microtubule stabilization by laulimalide and peloruside A.
Angew.Chem.Int.Ed.Engl., 53, 2014
4O4L
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TUBULIN-PELORUSIDE A-EPOTHILONE A COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Bargsten, K., Northcote, P.T., Marsh, M., Altmann, K.H., Miller, J.H., Diaz, J.F., Steinmetz, M.O.
Deposit date:2013-12-18
Release date:2014-03-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of microtubule stabilization by laulimalide and peloruside a.
Angew.Chem.Int.Ed.Engl., 53, 2014
4TUY
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TUBULIN-RHIZOXIN COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Bargsten, K., Diaz, J.F., Marsh, M., Cuevas, C., Liniger, M., Neuhaus, C., Andreu, J.M., Altmann, K.H., Steinmetz, M.O.
Deposit date:2014-06-25
Release date:2014-08-27
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TV8
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TUBULIN-MAYTANSINE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Bargsten, K., Diaz, J.F., Marsh, M., Cuevas, C., Liniger, M., Neuhaus, C., Andreu, J.M., Altmann, K.H., Steinmetz, M.O.
Deposit date:2014-06-26
Release date:2014-08-27
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TV9
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TUBULIN-PM060184 COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Bargsten, K., Diaz, J.F., Marsh, M., Cuevas, C., Liniger, M., Neuhaus, C., Andreu, J.M., Altmann, K.H., Steinmetz, M.O.
Deposit date:2014-06-26
Release date:2014-08-20
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Proc.Natl.Acad.Sci.USA, 111, 2014
5LA6
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TUBULIN-PIRONETIN COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Setter, J., Waight, A.B., Bargsten, K., Murga, J., Diaz, J.F., Steinmetz, M.O.
Deposit date:2016-06-13
Release date:2016-07-20
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pironetin Binds Covalently to alpha Cys316 and Perturbs a Major Loop and Helix of alpha-Tubulin to Inhibit Microtubule Formation.
J.Mol.Biol., 428, 2016
5LXS
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TUBULIN-KS-1-199-32 COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Steinmetz, M.O.
Deposit date:2016-09-22
Release date:2017-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of Microtubule Stabilization by Discodermolide.
Chembiochem, 18, 2017
5LXT
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TUBULIN-DISCODERMOLIDE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Steinmetz, M.O.
Deposit date:2016-09-22
Release date:2017-03-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Microtubule Stabilization by Discodermolide.
Chembiochem, 18, 2017
2GNN
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CRYSTAL STRUCTURE OF THE ORF VIRUS NZ2 VARIANT OF VEGF-E
Descriptor:Vascular endothelial growth factor homolog, CHLORIDE ION, SULFATE ION, ...
Authors:Prota, A.E., Pieren, M., Wagner, A., Kostrewa, D., Winkler, F.K., Ballmer-Hofer, K.
Deposit date:2006-04-10
Release date:2006-05-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Orf virus NZ2 variant of vascular endothelial growth factor-E. Implications for receptor specificity.
J.Biol.Chem., 281, 2006
5LOV
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DZ-2384 TUBULIN COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Steinmetz, M.O., Shore, G.C., Brouhard, G., Roulston, A.
Deposit date:2016-08-10
Release date:2016-11-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.
Sci Transl Med, 8, 2016
6FKJ
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TUBULIN-TUB075 COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Steinmetz, M.O., Priego, E.-M.
Deposit date:2018-01-24
Release date:2018-03-21
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.
Sci Rep, 8, 2018
6FKL
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TUBULIN-TUB015 COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Steinmetz, M.O., Priego, E.-M.
Deposit date:2018-01-24
Release date:2018-03-21
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.
Sci Rep, 8, 2018
1KKE
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CRYSTAL STRUCTURE OF REOVIRUS ATTACHMENT PROTEIN SIGMA1 TRIMER
Descriptor:SIGMA 1 PROTEIN
Authors:Chappell, J.D., Prota, A.E., Dermody, T.S., Stehle, T.
Deposit date:2001-12-07
Release date:2001-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiber.
EMBO J., 21, 2002
1XQO
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CRYSTAL STRUCTURE OF NATIVE PA-AGOG, 8-OXOGUANINE DNA GLYCOSYLASE FROM PYROBACULUM AEROPHILUM
Descriptor:8-oxoguanine DNA glycosylase
Authors:Lingaraju, G.M., Sartori, A.A., Kostrewa, D., Prota, A.E., Jiricny, J., Winkler, F.K.
Deposit date:2004-10-13
Release date:2004-11-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure
Structure, 13, 2005
170172
PDB entries from 2020-10-21