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1E2K
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KINETICS AND CRYSTAL STRUCTURE OF THE WILD-TYPE AND THE ENGINEERED Y101F MUTANT OF HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASE INTERACTING WITH (NORTH)-METHANOCARBA-THYMIDINE
Descriptor:THYMIDINE KINASE, SULFATE ION, 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE
Authors:Vogt, J., Scapozza, L., Schulz, G.E.
Deposit date:2000-05-23
Release date:2000-08-19
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine
Biochemistry, 39, 2000
1E2L
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KINETICS AND CRYSTAL STRUCTURE OF THE WILD-TYPE AND THE ENGINEERED Y101F MUTANT OF HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASE INTERACTING WITH (NORTH)-METHANOCARBA-THYMIDINE
Descriptor:THYMIDINE KINASE, SULFATE ION, 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE
Authors:Vogt, J., Scapozza, L., Schulz, G.E.
Deposit date:2000-05-23
Release date:2000-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine
Biochemistry, 39, 2000
5LP9
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FIMA WT FROM S. FLEXNERI
Descriptor:Major type 1 subunit fimbrin (Pilin)
Authors:Zyla, D., Capitani, G., Prota, A., Glockshuber, R.
Deposit date:2016-08-12
Release date:2017-12-20
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (0.886266 Å)
Cite:Alternative folding to a monomer or homopolymer is a common feature of the type 1 pilus subunit FimA from enteroinvasive bacteria.
J.Biol.Chem., 2019
5NKT
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FIMA WT FROM E. COLI
Descriptor:Type-1 fimbrial protein, A chain, SULFATE ION
Authors:Zyla, D., Capitani, G., Prota, A., Glockshuber, R.
Deposit date:2017-04-03
Release date:2018-05-16
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Alternative folding to a monomer or homopolymer is a common feature of the type 1 pilus subunit FimA from enteroinvasive bacteria.
J.Biol.Chem., 2019
6ERJ
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SELF-COMPLEMENTED FIMA SUBUNIT FROM SALMONELLA ENTERICA
Descriptor:Type-1 fimbrial protein, a chain, ACETIC ACID
Authors:Zyla, D.S., Prota, A., Capitani, G., Glockshuber, R.
Deposit date:2017-10-18
Release date:2019-01-30
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Alternative folding to a monomer or homopolymer is a common feature of the type 1 pilus subunit FimA from enteroinvasive bacteria.
J.Biol.Chem., 294, 2019
6YPZ
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PROMISCUOUS REDUCTASE LUGOII CATALYZES KETO-REDUCTION AT C1 DURING LUGDUNOMYCIN BIOSYNTHESIS
Descriptor:Monooxygenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Xiao, X., Elsayed, S.S., Wu, C., van der Heul, H., Prota, A., Huang, J., Guo, R., Abrahams, J.P., van Wezel, G.P.
Deposit date:2020-04-16
Release date:2020-09-16
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway.
Acs Chem.Biol., 2020
6YQ0
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PROMISCUOUS REDUCTASE LUGOII CATALYZES KETO-REDUCTION AT C1 DURING LUGDUNOMYCIN BIOSYNTHESIS
Descriptor:Monooxygenase, 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Xiao, X., Elsayed, S.S., Wu, C., van der Heul, H., Prota, A., Huang, J., Guo, R., Abrahams, J.P., van Wezel, G.P.
Deposit date:2020-04-16
Release date:2020-09-16
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway.
Acs Chem.Biol., 2020
6YQ3
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PROMISCUOUS REDUCTASE LUGOII CATALYZES KETO-REDUCTION AT C1 DURING LUGDUNOMYCIN BIOSYNTHESIS
Descriptor:Monooxygenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (3~{R})-8-methoxy-3-methyl-3,6-bis(oxidanyl)-2,4-dihydrobenzo[a]anthracene-1,7,12-trione, ...
Authors:Xiao, X., Elsayed, S.S., Wu, C., van der Heul, H., Prota, A., Huang, J., Guo, R., Abrahams, J.P., van Wezel, G.P.
Deposit date:2020-04-16
Release date:2020-09-16
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway.
Acs Chem.Biol., 2020
6YQ6
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PROMISCUOUS REDUCTASE LUGOII CATALYZES KETO-REDUCTION AT C1 DURING LUGDUNOMYCIN BIOSYNTHESIS
Descriptor:Monooxygenase, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Xiao, X., Elsayed, S.S., Wu, C., van der Heul, H., Prota, A., Huang, J., Guo, R., Abrahams, J.P., van Wezel, G.P.
Deposit date:2020-04-16
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway.
Acs Chem.Biol., 2020
1E2H
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THE NUCLEOSIDE BINDING SITE OF HERPES SIMPLEX TYPE 1 THYMIDINE KINASE ANALYZED BY X-RAY CRYSTALLOGRAPHY
Descriptor:THYMIDINE KINASE, SULFATE ION
Authors:Vogt, J., Scapozza, L., Schulz, G.E.
Deposit date:2000-05-23
Release date:2000-11-06
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography
Proteins: Struct.,Funct., Genet., 41, 2000
1E2I
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THE NUCLEOSIDE BINDING SITE OF HERPES SIMPLEX TYPE 1 THYMIDINE KINASE ANALYZED BY X-RAY CRYSTALLOGRAPHY
Descriptor:THYMIDINE KINASE, SULFATE ION, 9-HYDROXYPROPYLADENINE, ...
Authors:Vogt, J., Scapozza, L., Schulz, G.E.
Deposit date:2000-05-23
Release date:2000-11-06
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography
Proteins, 41, 2000
1E2J
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THE NUCLEOSIDE BINDING SITE OF HERPES SIMPLEX TYPE 1 THYMIDINE KINASE ANALYZED BY X-RAY CRYSTALLOGRAPHY
Descriptor:THYMIDINE KINASE, SULFATE ION, THYMIDINE
Authors:Vogt, J., Scapozza, L., Schulz, G.E.
Deposit date:2000-05-23
Release date:2000-11-06
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography
Proteins: Struct.,Funct., Genet., 41, 2000
3F0T
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CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH N-METHYL-DHBT
Descriptor:Thymidine kinase, SULFATE ION, N-Methyl-6-(1,3-dihydroxy-isobutyl)thymine
Authors:Pernot, L., Perozzo, R., Westermaier, Y., Martic, M., Ametamey, S., Scapozza, L.
Deposit date:2008-10-26
Release date:2009-11-03
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo.
Nucleosides Nucleotides Nucleic Acids, 30, 2011
3RDP
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CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH N-METHYL-FHBT
Descriptor:Thymidine kinase, SULFATE ION, 6-[(2R)-2-(fluoromethyl)-3-hydroxy-propyl]-1,5-dimethyl-pyrimidine-2,4-dione
Authors:Pernot, L., Perozzo, R., Westermaier, Y., Martic, M., Ametamey, S., Scapozza, L.
Deposit date:2011-04-01
Release date:2011-08-03
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo.
Nucleosides Nucleotides Nucleic Acids, 30, 2011
169117
PDB entries from 2020-09-23