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4GH8
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BU of 4gh8 by Molmil
Crystal structure of a 'humanized' E. coli dihydrofolate reductase
Descriptor: CALCIUM ION, Dihydrofolate reductase, METHOTREXATE, ...
Authors:French, J.B, Liu, C.T, Hanoian, P, Pringle, T.H, Hammes-Schiffer, S, Benkovic, S.J.
Deposit date:2012-08-07
Release date:2013-06-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Functional significance of evolving protein sequence in dihydrofolate reductase from bacteria to humans.
Proc.Natl.Acad.Sci.USA, 110, 2013

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