Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4U0C
DownloadVisualize
BU of 4u0c by Molmil
Hexameric HIV-1 CA in complex with Nup153 peptide, P6 crystal form
Descriptor: Capsid protein p24, Nuclear pore complex protein Nup153
Authors:Price, A.J, Jacques, D.A, James, L.C.
Deposit date:2014-07-11
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014
4U0B
DownloadVisualize
BU of 4u0b by Molmil
Hexamer HIV-1 CA in complex with CPSF6 peptide, P212121 crystal form
Descriptor: Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6
Authors:Price, A.J, Jacques, D.A, James, L.C.
Deposit date:2014-07-11
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014
4U0A
DownloadVisualize
BU of 4u0a by Molmil
Hexameric HIV-1 CA in complex with CPSF6 peptide, P6 crystal form
Descriptor: CHLORIDE ION, Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6
Authors:Price, A.J, Jacques, D.A, James, L.C.
Deposit date:2014-07-11
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014
4U0E
DownloadVisualize
BU of 4u0e by Molmil
Hexameric HIV-1 CA in complex with PF3450074
Descriptor: CHLORIDE ION, Capsid protein p24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
Authors:Price, A.J, Jacques, D.A, James, L.C.
Deposit date:2014-07-11
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014
4U0F
DownloadVisualize
BU of 4u0f by Molmil
Hexameric HIV-1 CA in Complex with BI-2
Descriptor: (4S)-4-(4-hydroxyphenyl)-3-phenyl-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one, 1,2-ETHANEDIOL, Capsid protein p24
Authors:Price, A.J, Jacques, D.A, James, L.C.
Deposit date:2014-07-11
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014
4U0D
DownloadVisualize
BU of 4u0d by Molmil
Hexameric HIV-1 CA in complex with Nup153 peptide, P212121 crystal form
Descriptor: CHLORIDE ION, Gag polyprotein, Nuclear pore complex protein Nup153
Authors:Price, A.J, Jacques, D.A, James, L.C.
Deposit date:2014-07-11
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014
4B4N
DownloadVisualize
BU of 4b4n by Molmil
CPSF6 defines a conserved capsid interface that modulates HIV-1 replication
Descriptor: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6, GAG PROTEIN
Authors:Price, A.J, James, L.C.
Deposit date:2012-07-31
Release date:2012-09-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.813 Å)
Cite:Cpsf6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication.
Plos Pathog., 8, 2012
2WLW
DownloadVisualize
BU of 2wlw by Molmil
Structure of the N-terminal capsid domain of HIV-2
Descriptor: PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
Authors:Price, A.J, Marzetta, F, Lammers, M, Ylinen, L.M.J, Schaller, T, Wilson, S.J, Towers, G.J, James, L.C.
Deposit date:2009-06-26
Release date:2009-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Active Site Remodelling Switches HIV Specificity of Antiretroviral Trimcyp
Nat.Struct.Mol.Biol., 16, 2009
2WLV
DownloadVisualize
BU of 2wlv by Molmil
Structure of the N-terminal capsid domain of HIV-2
Descriptor: GAG POLYPROTEIN
Authors:Price, A.J, Marzetta, F, Lammers, M, Ylinen, L.M.J, Schaller, T, Wilson, S.J, Towers, G.J, James, L.C.
Deposit date:2009-06-26
Release date:2009-09-22
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Active Site Remodelling Switches HIV Specificity of Antiretroviral Trimcyp
Nat.Struct.Mol.Biol., 16, 2009
4LQW
DownloadVisualize
BU of 4lqw by Molmil
Crystal structure of HIV-1 capsid N-terminal domain in complex with NUP358 cyclophilin
Descriptor: Capsid protein p24, E3 SUMO-protein ligase RanBP2
Authors:Price, A.J, James, L.C.
Deposit date:2013-07-19
Release date:2013-08-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358.
Retrovirology, 10, 2013
2X83
DownloadVisualize
BU of 2x83 by Molmil
Evolutionary basis of HIV restriction by the antiretroviral TRIMCyp
Descriptor: HIV-1 CAPSID, TRIM5/CypA fusion protein
Authors:Price, A.J, James, L.C.
Deposit date:2010-03-05
Release date:2010-09-15
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity.
Plos Pathog., 6, 2010
2X82
DownloadVisualize
BU of 2x82 by Molmil
Evolutionary basis of HIV restriction by the antiretroviral TRIMCyp
Descriptor: CAPSID PROTEIN P24
Authors:Price, A.J, James, L.C.
Deposit date:2010-03-05
Release date:2010-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Conformational Adaptation of Asian Macaque Trimcyp Directs Lineage Specific Antiviral Activity.
Plos Pathog., 6, 2010
4XRO
DownloadVisualize
BU of 4xro by Molmil
Disulfide stabilized HIV-1 CA hexamer 4mut (S41A, Q67H, V165I, L172I)
Descriptor: Capsid protein p24
Authors:Price, A.J, James, L.C.
Deposit date:2015-01-21
Release date:2015-07-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry.
J.Virol., 89, 2015
4XRQ
DownloadVisualize
BU of 4xrq by Molmil
Disulfide stabilized HIV-1 CA hexamer 4mut (S41A, Q67H, V165I, L172I) in complex with PF-3450074
Descriptor: Capsid protein p24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
Authors:Price, A.J, James, L.C.
Deposit date:2015-01-21
Release date:2015-07-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry.
J.Virol., 89, 2015
5HGL
DownloadVisualize
BU of 5hgl by Molmil
Hexameric HIV-1 CA, open conformation
Descriptor: CHLORIDE ION, Capsid protein P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
Authors:Price, A.J, Jacques, D.A, James, L.C.
Deposit date:2016-01-08
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis.
Nature, 536, 2016
4IPZ
DownloadVisualize
BU of 4ipz by Molmil
SmBz bound to Cyclophilin A
Descriptor: CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase A, cyclosporine SmBz-CsA
Authors:Price, A.J, Jacques, D.A, James, L.C.
Deposit date:2013-01-10
Release date:2013-11-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:HIV-1 evades innate immune recognition through specific cofactor recruitment.
Nature, 503, 2013
2JGD
DownloadVisualize
BU of 2jgd by Molmil
E. COLI 2-oxoglutarate dehydrogenase (E1o)
Descriptor: 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT, ADENOSINE MONOPHOSPHATE
Authors:Frank, R.A.W, Price, A.J, Northrop, F.D, Perham, R.N, Luisi, B.F.
Deposit date:2007-02-12
Release date:2007-02-27
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the E1 Component of the Escherichia Coli 2-Oxoglutarate Dehydrogenase Multienzyme Complex.
J.Mol.Biol., 368, 2007
5HGK
DownloadVisualize
BU of 5hgk by Molmil
HIV-1 CA N-terminal domain, open conformation
Descriptor: CHLORIDE ION, Capsid protein
Authors:Jacques, D.A, Price, A.J, James, L.C.
Deposit date:2016-01-08
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.763 Å)
Cite:HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis.
Nature, 536, 2016
5HGN
DownloadVisualize
BU of 5hgn by Molmil
Hexameric HIV-1 CA, apo form
Descriptor: Capsid protein P24
Authors:Jacques, D.A, Price, A.J, James, D.A.
Deposit date:2016-01-08
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis.
Nature, 536, 2016
4DGC
DownloadVisualize
BU of 4dgc by Molmil
TRIMCyp cyclophilin domain from Macaca mulatta: cyclosporin A complex
Descriptor: TRIMCyp, cyclosporin A
Authors:Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C.
Deposit date:2012-01-25
Release date:2012-02-08
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
4DGD
DownloadVisualize
BU of 4dgd by Molmil
TRIMCyp cyclophilin domain from Macaca mulatta: H70C mutant
Descriptor: GLYCEROL, TRIMCyp
Authors:Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C.
Deposit date:2012-01-25
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
4DGB
DownloadVisualize
BU of 4dgb by Molmil
TRIMCyp cyclophilin domain from Macaca mulatta: HIV-2 CA cyclophilin-binding loop complex
Descriptor: TRIMCyp, capsid protein
Authors:Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C.
Deposit date:2012-01-25
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
4DGA
DownloadVisualize
BU of 4dga by Molmil
TRIMCyp cyclophilin domain from Macaca mulatta: HIV-1 CA(O-loop) complex
Descriptor: TRIMCyp, capsid protein
Authors:Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C.
Deposit date:2012-01-25
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
4DGE
DownloadVisualize
BU of 4dge by Molmil
TRIMCyp cyclophilin domain from Macaca mulatta: H70C mutant, HIV-1 CA(O-loop) complex
Descriptor: TRIMCyp, capsid protein
Authors:Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C.
Deposit date:2012-01-25
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
7ZUD
DownloadVisualize
BU of 7zud by Molmil
Crystal structure of HIV-1 capsid IP6-CPSF6 complex
Descriptor: Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, INOSITOL HEXAKISPHOSPHATE
Authors:Nicastro, G, Taylor, I.A.
Deposit date:2022-05-12
Release date:2022-07-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:CP-MAS and Solution NMR Studies of Allosteric Communication in CA-assemblies of HIV-1.
J.Mol.Biol., 434, 2022

 

12>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon