Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2IW9
DownloadVisualize
BU of 2iw9 by Molmil
STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, MAGNESIUM ION, ...
Authors:Pratt, D.J, Bentley, J, Jewsbury, P, Boyle, F.T, Endicott, J.A, Noble, M.E.M.
Deposit date:2006-06-27
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dissecting the Determinants of Cyclin-Dependent Kinase 2 and Cyclin-Dependent Kinase 4 Inhibitor Selectivity.
J.Med.Chem., 49, 2006
2IW8
DownloadVisualize
BU of 2iw8 by Molmil
STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A F82H-L83V-H84D MUTANT WITH AN O6-CYCLOHEXYLMETHYLGUANINE INHIBITOR
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, MONOTHIOGLYCEROL, ...
Authors:Pratt, D.J, Bentley, J, Jewsbury, P, Boyle, F.T, Endicott, J.A, Noble, M.E.M.
Deposit date:2006-06-27
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dissecting the Determinants of Cyclin-Dependent Kinase 2 and Cyclin-Dependent Kinase 4 Inhibitor Selectivity.
J.Med.Chem., 49, 2006
2IW6
DownloadVisualize
BU of 2iw6 by Molmil
STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, MAGNESIUM ION, ...
Authors:Pratt, D.J, Bentley, J, Jewsbury, P, Boyle, F.T, Endicott, J.A, Noble, M.E.M.
Deposit date:2006-06-26
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dissecting the Determinants of Cyclin-Dependent Kinase 2 and Cyclin-Dependent Kinase 4 Inhibitor Selectivity.
J.Med.Chem., 49, 2006
1OGU
DownloadVisualize
BU of 1ogu by Molmil
STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 2-ARYLAMINO-4-CYCLOHEXYLMETHYL-5-NITROSO-6-AMINOPYRIMIDINE INHIBITOR
Descriptor: 4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ...
Authors:Pratt, D.J, Endicott, J.A, Noble, M.E.M.
Deposit date:2003-05-13
Release date:2003-09-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-Based Design of 2-Arylamino-4-Cyclohexyl Methyl-5-Nitroso-6-Aminopyrimidine Inhibitors of Cyclin-Dependent Kinases 1 and 2
Bioorg.Med.Chem.Lett., 13, 2003
1OI9
DownloadVisualize
BU of 1oi9 by Molmil
Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor
Descriptor: 6-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ...
Authors:Pratt, D.J, Endicott, J.A, Noble, M.E.M.
Deposit date:2003-06-10
Release date:2004-07-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2
J.Med.Chem., 47, 2004
1OIU
DownloadVisualize
BU of 1oiu by Molmil
Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor
Descriptor: 3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ...
Authors:Pratt, D.J, Endicott, J.A, Noble, M.E.M.
Deposit date:2003-06-26
Release date:2004-07-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2
J.Med.Chem., 47, 2004
1OIY
DownloadVisualize
BU of 1oiy by Molmil
Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor
Descriptor: 4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ...
Authors:Pratt, D.J, Endicott, J.A, Noble, M.E.M.
Deposit date:2003-06-26
Release date:2004-07-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2
J.Med.Chem., 47, 2004
1W8C
DownloadVisualize
BU of 1w8c by Molmil
CO-CRYSTAL STRUCTURE OF 6-CYCLOHEXYLMETHOXY-8-ISOPROPYL-9H-PURIN-2- YLAMINE AND MONOMERIC CDK2
Descriptor: 6-(CYCLOHEXYLMETHOXY)-8-ISOPROPYL-9H-PURIN-2-AMINE, CELL DIVISION PROTEIN KINASE 2
Authors:Pratt, D.J, Endicott, J.A, Noble, M.E.M.
Deposit date:2004-09-20
Release date:2006-08-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode.
J.Med.Chem., 57, 2014

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon