Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4Q5M
DownloadVisualize
BU of 4q5m by Molmil
D30N tethered HIV-1 protease dimer/saquinavir complex
Descriptor: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, Protease
Authors:Prashar, V, Bihani, S.C, Ferrer, J.L, Hosur, M.V.
Deposit date:2014-04-17
Release date:2015-04-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.795 Å)
Cite:Structural Basis of Why Nelfinavir-Resistant D30N Mutant of HIV-1 Protease Remains Susceptible to Saquinavir.
Chem.Biol.Drug Des., 86, 2015
2WHH
DownloadVisualize
BU of 2whh by Molmil
HIV-1 protease tethered dimer Q-product complex along with nucleophilic water molecule
Descriptor: GLUTAMIC ACID, PARA-NITROPHENYLALANINE, POL PROTEIN
Authors:Prashar, V, Bihani, S, Das, A, Ferrer, J.L, Hosur, M.V.
Deposit date:2009-05-05
Release date:2009-12-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Catalytic Water Co-Existing with a Product Peptide in the Active Site of HIV-1 Protease Revealed by X- Ray Structure Analysis.
Plos One, 4, 2009
3N3I
DownloadVisualize
BU of 3n3i by Molmil
Crystal Structure of G48V/C95F tethered HIV-1 Protease/Saquinavir complex
Descriptor: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, Protease
Authors:Prashar, V, Bihani, S.C, Das, A, Rao, D.R, Hosur, M.V.
Deposit date:2010-05-20
Release date:2010-06-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Insights into the mechanism of drug resistance: X-ray structure analysis of G48V/C95F tethered HIV-1 protease dimer/saquinavir complex
Biochem.Biophys.Res.Commun., 396, 2010
3DOX
DownloadVisualize
BU of 3dox by Molmil
X-ray structure of HIV-1 protease in situ product complex
Descriptor: A PEPTIDE SUBSTRATE-PIV, A PEPTIDE SUBSTRATE-SQNY, HIV-1 PROTEASE
Authors:Hosur, M.V, Ferrer, J.-L, Das, A, Prashar, V, Bihani, S.
Deposit date:2008-07-07
Release date:2008-09-09
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of HIV-1 protease in situ product complex
Proteins, 74, 2009
2NPH
DownloadVisualize
BU of 2nph by Molmil
Crystal structure of HIV1 protease in situ product complex
Descriptor: PROTEASE RETROPEPSIN, pentapeptide fragment, tetrapeptide fragment
Authors:Hosur, M.V, Das, A, Prashar, V.
Deposit date:2006-10-27
Release date:2006-12-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates
Proc.Natl.Acad.Sci.Usa, 103, 2006
5YRS
DownloadVisualize
BU of 5yrs by Molmil
X-ray Snapshot of HIV-1 Protease in Action: Observation of Tetrahedral Intermediate and Its SIHB with Catalytic Aspartate
Descriptor: PROTEASE, RT-RH oligopeprtide
Authors:Das, A, Mahale, S, Prashar, V, Bihani, S, Ferrer, J.-L, Hosur, M.V.
Deposit date:2017-11-10
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:X-ray snapshot of HIV-1 protease in action: observation of tetrahedral intermediate and short ionic hydrogen bond SIHB with catalytic aspartate.
J. Am. Chem. Soc., 132, 2010
3KT2
DownloadVisualize
BU of 3kt2 by Molmil
Crystal Structure of N88D mutant HIV-1 Protease
Descriptor: Protease
Authors:Bihani, S.C, Das, A, Prashar, V, Ferrer, J.L, Hosur, M.V.
Deposit date:2009-11-24
Release date:2010-02-16
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:Resistance mechanism revealed by crystal structures of unliganded nelfinavir-resistant HIV-1 protease non-active site mutants N88D and N88S.
Biochem.Biophys.Res.Commun., 389, 2009
3KT5
DownloadVisualize
BU of 3kt5 by Molmil
Crystal Structure of N88S mutant HIV-1 Protease
Descriptor: Protease
Authors:Bihani, S.C, Das, A, Prashar, V, Ferrer, J.L, Hosur, M.V.
Deposit date:2009-11-24
Release date:2010-02-16
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Resistance mechanism revealed by crystal structures of unliganded nelfinavir-resistant HIV-1 protease non-active site mutants N88D and N88S.
Biochem.Biophys.Res.Commun., 389, 2009
3Q3Q
DownloadVisualize
BU of 3q3q by Molmil
Crystal Structure of SPAP: an novel alkaline phosphatase from bacterium Sphingomonas sp. strain BSAR-1
Descriptor: Alkaline phosphatase, CALCIUM ION, GLYCEROL, ...
Authors:Bihani, S.C, Hosur, M.V.
Deposit date:2010-12-22
Release date:2011-12-28
Method:X-RAY DIFFRACTION (1.953 Å)
Cite:X-ray structure reveals a new class and provides insight into evolution of alkaline phosphatases
Plos One, 6, 2011
3IX0
DownloadVisualize
BU of 3ix0 by Molmil
Crystal structure of human seminal plasma protein PSP94
Descriptor: Beta-microseminoprotein
Authors:Kumar, M, Kumar, A, Jagtap, D.D, Mahale, S.D.
Deposit date:2009-09-03
Release date:2010-03-16
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of prostate secretory protein PSP94 shows an edge-to-edge association of two monomers to form a homodimer
J.Mol.Biol., 397, 2010

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon