1F5N
 
 | | HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP. | | Descriptor: | INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | Authors: | Prakash, B, Renault, L, Praefcke, G.J.K, Herrmann, C, Wittinghofer, A. | | Deposit date: | 2000-06-15 | | Release date: | 2000-09-27 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism.
EMBO J., 19, 2000
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1DG3
 | | STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM | | Descriptor: | PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1) | | Authors: | Prakash, B, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | | Deposit date: | 1999-11-23 | | Release date: | 2000-10-11 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins.
Nature, 403, 2000
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1O7F
 | | CRYSTAL STRUCTURE OF THE REGULATORY DOMAIN OF EPAC2 | | Descriptor: | CAMP-DEPENDENT RAP1 GUANINE-NUCLEOTIDE EXCHANGE FACTOR | | Authors: | Rehmann, H, Prakash, B, Wolf, E, Rueppel, A, De Rooij, J, Bos, J.L, Wittinghofer, A. | | Deposit date: | 2002-11-04 | | Release date: | 2002-11-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure and Regulation of the Camp-Binding Domains of Epac2
Nat.Struct.Biol., 10, 2002
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7BVU
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7BWV
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7C1O
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3DJ4
 | | Crystal Structure of GlmU from Mycobacterium tuberculosis in complex with URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE. | | Descriptor: | Bifunctional protein glmU, COBALT (II) ION, MAGNESIUM ION, ... | | Authors: | Verma, S.K, Prakash, B. | | Deposit date: | 2008-06-22 | | Release date: | 2009-05-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | PknB-mediated phosphorylation of a novel substrate, N-acetylglucosamine-1-phosphate uridyltransferase, modulates its acetyltransferase activity.
J.Mol.Biol., 386, 2009
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3DK5
 | | Crystal Structure of Apo-GlmU from Mycobacterium tuberculosis | | Descriptor: | Bifunctional protein glmU, MAGNESIUM ION | | Authors: | Verma, S.K, Prakash, B. | | Deposit date: | 2008-06-24 | | Release date: | 2009-05-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | PknB-mediated phosphorylation of a novel substrate, N-acetylglucosamine-1-phosphate uridyltransferase, modulates its acetyltransferase activity.
J.Mol.Biol., 386, 2009
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3FOQ
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4G3P
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4G3Q
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4G3S
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4G87
 | | Crystal structure of GLMU from Mycobacterium tuberculosis snapshot 1 | | Descriptor: | Bifunctional protein GlmU, COBALT (II) ION, MAGNESIUM ION, ... | | Authors: | Jagtap, P.A, Verma, S.K, Prakash, B. | | Deposit date: | 2012-07-22 | | Release date: | 2013-03-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Crystal structures identify an atypical two-metal-ion mechanism for uridyltransfer in GlmU: its significance to sugar nucleotidyl transferases
J.Mol.Biol., 425, 2013
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4K6R
 | | Crystal structure of GlmU in complex with ATP | | Descriptor: | 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional protein GlmU, ... | | Authors: | Vithani, N, Prakash, B. | | Deposit date: | 2013-04-16 | | Release date: | 2014-04-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | GlmU (N-acetylglucosamine-1-phosphate uridyltransferase) bound to three magnesium ions and ATP at the active site.
Acta Crystallogr.,Sect.F, 70, 2014
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3ST8
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3SPT
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5X4B
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4HCQ
 | | Crystal structure of GLMU from mycobacterium tuberculosis in complex with glucosamine-1-phosphate | | Descriptor: | 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, Bifunctional protein GlmU, COBALT (II) ION, ... | | Authors: | Jagtap, P.K.A, Verma, S.K, Vithani, N. | | Deposit date: | 2012-10-01 | | Release date: | 2013-03-13 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structures identify an atypical two-metal-ion mechanism for uridyltransfer in GlmU: its significance to sugar nucleotidyl transferases
J.Mol.Biol., 425, 2013
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2B8W
 | | Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP/AlF4 | | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, ... | | Authors: | Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | | Deposit date: | 2005-10-10 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
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2B92
 | | Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GDP/AlF3 | | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Interferon-induced guanylate-binding protein 1, ... | | Authors: | Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | | Deposit date: | 2005-10-10 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
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2BC9
 | | Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with non-hydrolysable GTP analogue GppNHp | | Descriptor: | Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | Authors: | Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | | Deposit date: | 2005-10-19 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
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2D4H
 | | Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP | | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Interferon-induced guanylate-binding protein 1 | | Authors: | Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | | Deposit date: | 2005-10-19 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
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3CF6
 | | Structure of Epac2 in complex with cyclic-AMP and Rap | | Descriptor: | 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, Rap guanine nucleotide exchange factor (GEF) 4, Ras-related protein Rap-1b, ... | | Authors: | Rehmann, H, Arias-Palomo, E, Hadders, M.A, Schwede, F, Llorca, O, Bos, J.L. | | Deposit date: | 2008-03-02 | | Release date: | 2008-07-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
Nature, 455, 2008
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2BYV
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