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4M4X
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BU of 4m4x by Molmil
Structure and Dimerization Properties of the Aryl Hydrocarbon Receptor (AHR) PAS-A Domain
Descriptor: Aryl hydrocarbon receptor
Authors:Wu, D, Potluri, N, Kim, Y, Rastinejad, F.
Deposit date:2013-08-07
Release date:2013-09-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain.
Mol.Cell.Biol., 33, 2013
6E3S
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BU of 6e3s by Molmil
Crystal Structure of the Heterodimeric HIF-2 Complex with Antagonist PT2385
Descriptor: 3-{[(1S)-2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
Authors:Wu, D, Su, X, Lu, J, Li, S, Hood, B, Vasile, S, Potluri, N, Diao, X, Kim, Y, Khorasanizadeh, S, Rastinejad, F.
Deposit date:2018-07-15
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Bidirectional modulation of HIF-2 activity through chemical ligands.
Nat. Chem. Biol., 15, 2019
6E3T
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BU of 6e3t by Molmil
Crystal Structure of the Heterodimeric HIF-2 Complex with Antagonist T1001
Descriptor: (6S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
Authors:Wu, D, Su, X, Lu, J, Li, S, Hood, B, Vasile, S, Potluri, N, Diao, X, Kim, Y, Khorasanizadeh, S, Rastinejad, F.
Deposit date:2018-07-15
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Bidirectional modulation of HIF-2 activity through chemical ligands.
Nat. Chem. Biol., 15, 2019
6E3U
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BU of 6e3u by Molmil
Crystal Structure of the Heterodimeric HIF-2 Complex with Agonist M1001
Descriptor: 3-{[2-(pyrrolidin-1-yl)phenyl]amino}-1H-1lambda~6~,2-benzothiazole-1,1-dione, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
Authors:Wu, D, Su, X, Lu, J, Li, S, Hood, B, Vasile, S, Potluri, N, Diao, X, Kim, Y, Khorasanizadeh, S, Rastinejad, F.
Deposit date:2018-07-15
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Bidirectional modulation of HIF-2 activity through chemical ligands.
Nat. Chem. Biol., 15, 2019
4ZQD
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BU of 4zqd by Molmil
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with the Benzoxadiazole Antagonist 0X3
Descriptor: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
Authors:Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F.
Deposit date:2015-05-09
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZPR
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BU of 4zpr by Molmil
Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA
Descriptor: Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ...
Authors:Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F.
Deposit date:2015-05-08
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.902 Å)
Cite:Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZPK
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BU of 4zpk by Molmil
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with HRE DNA
Descriptor: Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ...
Authors:Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F.
Deposit date:2015-05-08
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZP4
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BU of 4zp4 by Molmil
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex
Descriptor: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
Authors:Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F.
Deposit date:2015-05-07
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.355 Å)
Cite:Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZPH
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BU of 4zph by Molmil
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with Proflavine
Descriptor: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, PROFLAVIN
Authors:Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F.
Deposit date:2015-05-07
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
5SY5
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BU of 5sy5 by Molmil
Crystal Structure of the Heterodimeric NPAS1-ARNT Complex
Descriptor: Aryl hydrocarbon receptor nuclear translocator, Neuronal PAS domain-containing protein 1
Authors:Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F.
Deposit date:2016-08-10
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.
Elife, 5, 2016
5SY7
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BU of 5sy7 by Molmil
Crystal Structure of the Heterodimeric NPAS3-ARNT Complex with HRE DNA
Descriptor: Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ...
Authors:Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F.
Deposit date:2016-08-10
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.
Elife, 5, 2016
4IQR
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BU of 4iqr by Molmil
Multi-Domain Organization of the HNF4alpha Nuclear Receptor Complex on DNA
Descriptor: DNA (5'-D(*CP*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), Hepatocyte nuclear factor 4-alpha, ...
Authors:Chandra, V, Huang, P, Kim, Y, Rastinejad, F.
Deposit date:2013-01-13
Release date:2013-03-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Multidomain integration in the structure of the HNF-4 alpha nuclear receptor complex.
Nature, 495, 2013
5TFP
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BU of 5tfp by Molmil
Crystal Structure of the SETDB2 Amino Terminal Domain
Descriptor: GLYCEROL, Histone-lysine N-methyltransferase SETDB2, L(+)-TARTARIC ACID
Authors:Khorasanizadeh, S, Kim, Y.
Deposit date:2016-09-26
Release date:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a helical dimerization domain in SETDB2 lysine methyltransferase
To Be Published
5UAN
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BU of 5uan by Molmil
Crystal structure of multi-domain RAR-beta-RXR-alpha heterodimer on DNA
Descriptor: (9cis)-retinoic acid, DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*AP*G)-3'), ...
Authors:Chandra, V, Wu, D, Kim, Y, Rastinejad, F.
Deposit date:2016-12-19
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.508 Å)
Cite:The quaternary architecture of RAR beta-RXR alpha heterodimer facilitates domain-domain signal transmission.
Nat Commun, 8, 2017

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PDB entries from 2024-03-27

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