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1CN2
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SOLUTION STRUCTURE OF TOXIN 2 FROM CENTRUROIDES NOXIUS HOFFMANN, A BETA SCORPION NEUROTOXIN ACTING ON SODIUM CHANNELS, NMR, 15 STRUCTURES
Descriptor: TOXIN 2
Authors:Pintar, A, Possani, L.D, Delepierre, M.
Deposit date:1998-06-21
Release date:1999-01-13
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels.
J.Mol.Biol., 287, 1999
2AXK
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BU of 2axk by Molmil
Solution structure of discrepin, a scorpion venom toxin blocking K+ channels.
Descriptor: discrepin
Authors:Prochnicka-Chalufour, A, Corzo, G, Satake, H, Martin-Eauclaire, M.-F, Murgia, A.R, Prestipino, G, D'Suze, G, Possani, L.D, Delepierre, M.
Deposit date:2005-09-05
Release date:2006-06-20
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily.
Biochemistry, 45, 2006
1N8M
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BU of 1n8m by Molmil
Solution structure of Pi4, a four disulfide bridged scorpion toxin active on potassium channels
Descriptor: Potassium channel blocking toxin 4
Authors:Guijarro, J.I, M'Barek, S, Olamendi-Portugal, T, Gomez-Lagunas, F, Garnier, D, Rochat, H, Possani, L.D, Sabatier, J.M, Delepierre, M.
Deposit date:2002-11-21
Release date:2003-09-02
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels.
Protein Sci., 12, 2003
6NW8
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SOLUTION STRUCTURE OF CN29, A TOXIN FROM CENTRUROIDES NOXIUS SCORPION VENOM
Descriptor: Cn29
Authors:Delepierre, M, Gurrola, G.B, Possani, L.D, Guijarro, J.I.
Deposit date:2019-02-06
Release date:2019-07-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Cn29, a novel orphan peptide found in the venom of the scorpion Centruroides noxius: Structure and function.
Toxicon, 167, 2019
1QKY
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Solution structure of PI7, a non toxic peptide isolated from the scorpion Pandinus Imperator.
Descriptor: TOXIN 7 FROM PANDINUS IMPERATOR
Authors:Delepierre, M, Prochnicka-Chalufour, A, Boisbouvier, J, Possani, L.D.
Deposit date:1999-08-17
Release date:2000-02-03
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Pi7, an orphan peptide from the scorpion Pandinus imperator: a 1H-NMR analysis using a nano-NMR Probe.
Biochemistry, 38, 1999
2YBR
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Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann
Descriptor: BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT 9004G
Authors:Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A.
Deposit date:2011-03-09
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment
J.Biol.Chem., 286, 2011
2YC1
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Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann
Descriptor: BETA-MAMMAL TOXIN CN2, GLYCEROL, SINGLE CHAIN ANTIBODY FRAGMENT 9004G
Authors:Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A.
Deposit date:2011-03-10
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment.
J.Biol.Chem., 286, 2011
1PE4
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SOLUTION STRUCTURE OF TOXIN CN12 FROM CENTRUROIDES NOXIUS ALFA SCORPION TOXIN ACTING ON SODIUM CHANNELS. NMR STRUCTURE
Descriptor: Neurotoxin Cn11
Authors:Del Rio-Portilla, F, Hernandez-Marin, E, Pimienta, G, Coronas, F.V, Zamudio, F.Z, Rodrguez de la Vega, R.C, Wanke, E, Possani, L.D.
Deposit date:2003-05-21
Release date:2004-05-25
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity.
Eur.J.Biochem., 271, 2004
1PX9
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Solution structure of the native CnErg1 Ergtoxin, a highly specific inhibitor of HERG channel
Descriptor: ergtoxin
Authors:Frenal, K, Wecker, K, Gurrola, G.B, Possani, L.D, Wolff, N, Delepierre, M.
Deposit date:2003-07-03
Release date:2004-06-22
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels.
Proteins, 56, 2004
1SXM
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SCORPION TOXIN (NOXIUSTOXIN) WITH HIGH AFFINITY FOR VOLTAGE DEPENDENT POTASSIUM CHANNEL AND LOW AFFINITY FOR CALCIUM DEPENDENT POTASSIUM CHANNEL (NMR AT 20 DEGREES, PH3.5, 39 STRUCTURES)
Descriptor: NOXIUSTOXIN
Authors:Dauplais, M, Gilquin, B, Possani, L.D, Gurrola-Briones, G, Roumestand, C, Menez, A.
Deposit date:1995-09-07
Release date:1996-01-29
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins.
Biochemistry, 34, 1995
2KGH
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Solution structure of Brachyperma ruhnaui toxin 2
Descriptor: Venom peptide 2
Authors:Corzo, G, Bernard, C, Clement, H, Bosmans, F, Tygat, J, Possani, L.D, Darbon, H, Alagon, A.
Deposit date:2009-03-12
Release date:2009-12-15
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2.
Biochim.Biophys.Acta, 1794, 2009
2KJA
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Chemical shift assignments, constraints, and coordinates for CN5 scorpion toxin
Descriptor: Beta-toxin Cn5
Authors:Prochnicka-Chalufour, A, Corzo, G, Garcia, B.I, Possani, L.D, Delepierre, M.
Deposit date:2009-05-26
Release date:2009-10-06
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus.
Biochim.Biophys.Acta, 1794, 2009
2LJM
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Solution Structure of CssII
Descriptor: Beta-mammal toxin Css2
Authors:del Rio-Portilla, F, Saucedo, A.L, Corzo, G, Delepierre, M, Possani, L.D.
Deposit date:2011-09-20
Release date:2012-02-15
Method:SOLUTION NMR
Cite:Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels.
Biochim.Biophys.Acta, 1824, 2012
2LI7
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Solution Structure of CssII
Descriptor: Beta-mammal toxin Css2
Authors:del Rio-Portilla, F, Saucedo, A.L, Corzo, G, Delepierre, M, Possani, L.D.
Deposit date:2011-08-24
Release date:2012-02-15
Method:SOLUTION NMR
Cite:Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels.
Biochim.Biophys.Acta, 1824, 2012
4V1D
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Ternary complex among two human derived single chain antibody fragments and Cn2 toxin from scorpion Centruroides noxius.
Descriptor: BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT LR, HEAVY CHAIN, ...
Authors:Riano-Umbarila, L, Serrano-Posada, H, Rojas-Trejo, S, Rudino-Pinera, E, Becerril, B.
Deposit date:2014-09-25
Release date:2015-10-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Optimal Neutralization of Centruroides Noxius Venom is Understood Through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin.
J.Biol.Chem., 291, 2016
6MRQ
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BU of 6mrq by Molmil
Structure of ToPI1 inhibitor from Tityus obscurus scorpion venom in complex with trypsin
Descriptor: CALCIUM ION, Cationic trypsin, SULFATE ION, ...
Authors:Fernandes, J.C, Mourao, C.B.F, Schwartz, E.F, Barbosa, J.A.R.G.
Deposit date:2018-10-15
Release date:2020-07-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.288 Å)
Cite:Head-to-Tail Cyclization after Interaction with Trypsin: A Scorpion Venom Peptide that Resembles Plant Cyclotides.
J.Med.Chem., 63, 2020
6VXW
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NMR solution structure of natural scorpion toxin Cl13
Descriptor: Beta-toxin Cl13
Authors:del Rio Portilla, F, Delepierre, M, Lopez Giraldo, A.E.
Deposit date:2020-02-24
Release date:2020-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus.
Toxicon, 184, 2020
7M1E
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Structural and functional studies about scorpine showed the presence of blocking channel and cytolytic activities as well as two different structural domains
Descriptor: Scorpine
Authors:del Rio, J.F, Lopez, A.E, Titaux, G.
Deposit date:2021-03-12
Release date:2022-01-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and functional studies of scorpine: A channel blocker and cytolytic peptide.
Toxicon, 222, 2022
7M1D
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Structural and functional studies about scorpine showed the presence of blocking channel and cytolytic activities as well as two different structural domains
Descriptor: Scorpine
Authors:del Rio-Portilla, F, Lopez-Giraldo, A.E.
Deposit date:2021-03-12
Release date:2022-01-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and functional studies of scorpine: A channel blocker and cytolytic peptide.
Toxicon, 222, 2022
6MZT
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Solution structure of alpha-KTx-6.21 (UroTx) from Urodacus yaschenkoi
Descriptor: Potassium channel toxin alpha-KTx 6.21
Authors:Chin, Y.K.-Y, Luna-Ramirez, K, Anangi, R, King, G.F.
Deposit date:2018-11-05
Release date:2020-03-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom.
Biochem. Pharmacol., 174, 2020
2K9O
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Solution structure of Vm24 synthetic scorpion toxin
Descriptor: Vm24 SCORPION toxin
Authors:del Rio-Portilla, F, Hernandez-Lopez, R, Possani-Postay, L, Gurrola, G.
Deposit date:2008-10-20
Release date:2009-11-03
Last modified:2014-05-28
Method:SOLUTION NMR
Cite:Structure, function, and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes.
Biochemistry, 51, 2012
1NE5
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BU of 1ne5 by Molmil
Solution Structure of HERG Specific Scorpion Toxin CnErg1
Descriptor: ergtoxin
Authors:Torres, A.M, Paramjit, B, Alewood, P, Kuchel, P.W, Vandenberg, J.I.
Deposit date:2002-12-10
Release date:2003-04-01
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin
FEBS Lett., 539, 2003
7ZRU
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Solution structure of Pi6, a low affinity blocking kappa-K+-channel peptide from the scorpion Pandinus imperator
Descriptor: Potassium channel toxin kappa-KTx 2.9
Authors:Delepierre, M, Olamendi Portugal, T, Possani, L.D, Guijarro, J.I.
Deposit date:2022-05-05
Release date:2022-05-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Not applicable
Not Published
2LO7
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Ts16 NMR solution structure
Descriptor: Toxin Ts16
Authors:del Rio-Portilla, F, Saucedo, A.L, Flores-Solis, D.
Deposit date:2012-01-17
Release date:2012-03-14
Last modified:2014-01-15
Method:SOLUTION NMR
Cite:New Tricks of an Old Pattern: STRUCTURAL VERSATILITY OF SCORPION TOXINS WITH COMMON CYSTEINE SPACING.
J.Biol.Chem., 287, 2012
2LI3
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Structural and functional analysis of a novel potassium toxin argentinean scorpion Tityus trivittatus reveals a new kappa sub-family
Descriptor: Potassium channel toxin kappa-KTX3.1
Authors:Saucedo-Yanez, A, Del Rio-Portilla, F, Hernandez-Lopez, R.
Deposit date:2011-08-19
Release date:2012-01-11
Last modified:2012-04-25
Method:SOLUTION NMR
Cite:New Tricks of an Old Pattern: STRUCTURAL VERSATILITY OF SCORPION TOXINS WITH COMMON CYSTEINE SPACING.
J.Biol.Chem., 287, 2012

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