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5EJF
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CRYSTAL STRUCTURE OF NAD KINASE P101A MUTANT FROM LISTERIA MONOCYTOGENES
Descriptor:NAD kinase 1
Authors:Poncet-Montange, G., Assairi, L., Gelin, M., Pochet, S., Labesse, G.
Deposit date:2015-11-01
Release date:2016-11-09
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of NAD kinase 1 from Listeria monocytogenes: P101A mutant
to be published
5EJG
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CRYSTAL STRUCTURE OF NAD KINASE P252D MUTANT FROM LISTERIA MONOCYTOGENES
Descriptor:NAD kinase 1
Authors:Poncet-Montange, G., Assairi, L., Gelin, M., Pochet, S., Labesse, G.
Deposit date:2015-11-01
Release date:2016-11-09
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.877 Å)
Cite:Crystal structure of NAD kinase 1 from Listeria monocytogenes: P252D mutant
to be published
5EJH
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CRYSTAL STRUCTURE OF NAD KINASE V98S MUTANT FROM LISTERIA MONOCYTOGENES
Descriptor:NAD kinase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRIC ACID
Authors:Poncet-Montange, G., Assairi, L., Gelin, M., Pochet, S., Labesse, G.
Deposit date:2015-11-01
Release date:2016-11-09
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of NAD kinase 1 from Listeria monocytogenes: V98S mutant
to be published
5EJI
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CRYSTAL STRUCTURE OF NAD KINASE W78F MUTANT FROM LISTERIA MONOCYTOGENES IN COMPLEX WITH NADP/MN++/PPI
Descriptor:NAD kinase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, MANGANESE (II) ION, ...
Authors:Poncet-Montange, G., Assairi, L., Gelin, M., Pochet, S., Labesse, G.
Deposit date:2015-11-01
Release date:2016-11-09
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.292 Å)
Cite:Crystal structure of NAD kinase W78F mutant from Listeria monocytogenes in complex with NADP/Mn++/PPi
to be published
2I1W
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CRYSTAL STRUCTURE OF NAD KINASE 1 FROM LISTERIA MONOCYTOGENES
Descriptor:Probable inorganic polyphosphate/ATP-NAD kinase 1, IODIDE ION
Authors:Poncet-Montange, G., Assairi, L., Arold, S., Pochet, S., Labesse, G.
Deposit date:2006-08-15
Release date:2007-08-07
Last modified:2020-06-24
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
2I29
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CRYSTAL STRUCTURE OF NAD KINASE 1 FROM LISTERIA MONOCYTOGENES
Descriptor:Probable inorganic polyphosphate/ATP-NAD kinase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, CITRIC ACID
Authors:Poncet-Montange, G., Assairi, L., Arold, S., Pochet, S., Labesse, G.
Deposit date:2006-08-16
Release date:2007-08-07
Last modified:2020-06-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
2I2B
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CRYSTAL STRUCTURE OF LMNADK1 FROM LISTERIA MONOCYTOGENES
Descriptor:Probable inorganic polyphosphate/ATP-NAD kinase 1, BETA-D-ERYTHROFURANOSYL-ADENOSINE, CITRIC ACID, ...
Authors:Poncet-Montange, G., Labesse, G.
Deposit date:2006-08-16
Release date:2007-08-07
Last modified:2020-06-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
2I2C
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CRYSTAL STRUCTURE OF LMNADK1
Descriptor:Probable inorganic polyphosphate/ATP-NAD kinase 1, (2S,3S,4R,5R,2'S,3'S,4'R,5'R)-2,2'-[DITHIOBIS(METHYLENE)]BIS[5-(6-AMINO-9H-PURIN-9-YL)TETRAHYDROFURAN-3,4-DIOL], TETRAETHYLENE GLYCOL
Authors:Poncet-Montange, G., Labesse, G.
Deposit date:2006-08-16
Release date:2007-08-07
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
2I2D
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CRYSTAL STRUCTURE OF LMNADK1
Descriptor:Probable inorganic polyphosphate/ATP-NAD kinase 1, BIS{[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL} DIHYDROGEN DIPHOSPHATE, CITRIC ACID
Authors:Poncet-Montange, G., Labesse, G.
Deposit date:2006-08-16
Release date:2007-08-07
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
2I2F
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CRYSTAL STRUCTURE OF LMNADK1
Descriptor:Probable inorganic polyphosphate/ATP-NAD kinase 1, PHOSPHATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Poncet-Montange, G., Assairi, L., Arold, S., Pochet, S., Labesse, G.
Deposit date:2006-08-16
Release date:2007-08-07
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
2NTN
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CRYSTAL STRUCTURE OF MABA-C60V/G139A/S144L
Descriptor:3-oxoacyl-[acyl-carrier-protein] reductase
Authors:Poncet-Montange, G., Ducasse-Cabanot, S., Quemard, A., Labesse, G., Cohen-Gonsaud, M.
Deposit date:2006-11-08
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Lack of dynamics in the MabA active site kills the enzyme activity: practical consequences for drug-design studies
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2Q5F
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CRYSTAL STRUCTURE OF LMNADK1 FROM LISTERIA MONOCYTOGENES
Descriptor:Probable inorganic polyphosphate/ATP-NAD kinase 1, (2S,3S,4R,5R,2'S,3'S,4'R,5'R)-2,2'-[DITHIOBIS(METHYLENE)]BIS[5-(6-AMINO-9H-PURIN-9-YL)TETRAHYDROFURAN-3,4-DIOL]
Authors:Poncet-Montange, G., Assairi, L., Arold, S., Pochet, S., Labesse, G.
Deposit date:2007-06-01
Release date:2007-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
4DY6
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CRYSTAL STRUCTURE OF NAD KINASE 1 FROM LISTERIA MONOCYTOGENES IN COMPLEX WITH 2'-PHOSPHATE BIS(ADENOSINE)-5'-DIPHOSPHATE
Descriptor:inorganic polyphosphate/ATP-NAD kinase 1, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, CITRIC ACID
Authors:Poncet-Montange, G., Assairi, L., Arold, S., Pochet, S., Labesse, G.
Deposit date:2012-02-28
Release date:2012-03-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
4TT2
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH H4(1-20)K5AC PEPTIDE
Descriptor:ATPase family AAA domain-containing protein 2, Histone H4K5Ac
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-19
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TT4
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH H3(1-21)K14AC PEPTIDE
Descriptor:ATPase family AAA domain-containing protein 2, Histone H3(1-21)K4Ac, SULFATE ION, ...
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-19
Release date:2014-12-24
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TT6
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN DOUBLE MUTANT N1063A-Y1064A IN APO FORM
Descriptor:ATPase family AAA domain-containing protein 2, SULFATE ION, CHLORIDE ION, ...
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-19
Release date:2014-12-24
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TTE
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH METHYL 3-AMINO-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)BENZOATE
Descriptor:ATPase family AAA domain-containing protein 2, SULFATE ION, CHLORIDE ION, ...
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-20
Release date:2014-12-24
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TU4
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH 3-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-5-[(PHENYLSULFONYL)AMINO]BENZOICACID
Descriptor:ATPase family AAA domain-containing protein 2, SULFATE ION, GLYCEROL, ...
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-23
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TU6
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CRYSTAL STRUCTURE OF APO ATAD2A BROMODOMAIN WITH N1064 ALTERNATE CONFORMATION
Descriptor:ATPase family AAA domain-containing protein 2, SULFATE ION
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-23
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4YAB
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH 1-METHYL-5-(2-METHYL-1 3-THIAZOL-4-YL)-2 3-DIHYDRO-1H-INDOL-2-ONE (1)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, 1-methyl-5-(2-methyl-1,3-thiazol-4-yl)-1,3-dihydro-2H-indol-2-one, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-17
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YAD
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH 2,4-DIMETHOXY-N-(1-METHYL-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-6-YL)BENZENE-1-SULFONAMIDE (3B)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, 2,4-dimethoxy-N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)benzenesulfonamide, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-17
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YAT
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH N-(1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL)-4-METHOXYBENZENE-1-SULFONAMIDE (5B)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, N-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-4-methoxybenzenesulfonamide
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-17
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YAX
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH N-[6-(4-METHOXYPHENOXY)-1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL]BENZENESULFONAMIDE (5G)
Descriptor:Transcription intermediary factor 1-alpha, N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl]benzenesulfonamide, ZINC ION, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-18
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YBM
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH N-{6-[3-(BENZYLOXY)PHENOXY]-1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL}-3,4-DIMETHOXYBENZENE-1-SULFONAMIDE (7B)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, GLYCEROL, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-18
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YBS
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH N-{1,3-DIMETHYL-6-[3-(2-METHYLPROPOXY)PHENOXY]-2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL}-1,2-DIMETHYL-1H-IMIDAZOLE-4-SULFONAMIDE (7G)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, N-{1,3-dimethyl-6-[3-(2-methylpropoxy)phenoxy]-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl}-1,2-dimethyl-1H-imidazole-4-sulfonamide, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-19
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
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170172
PDB entries from 2020-10-21