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1YG9
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BU of 1yg9 by Molmil
The structure of mutant (N93Q) of bla g 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aspartic protease Bla g 2, ...
Authors:Li, M, Gustchina, A, Wuenschmann, S, Pomes, A, Wlodawer, A.
Deposit date:2005-01-04
Release date:2005-03-22
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of cockroach allergen Bla g 2, an unusual zinc binding aspartic protease with a novel mode of self-inhibition.
J.Mol.Biol., 348, 2005
2NR6
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BU of 2nr6 by Molmil
Crystal structure of the complex of antibody and the allergen Bla g 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, ...
Authors:Li, M, Gustchina, A, Wlodawer, A, Pomes, A, Wunschmann, S.
Deposit date:2006-11-01
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody.
J.Biol.Chem., 283, 2008
4ZCE
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BU of 4zce by Molmil
Crystal Structure of the dust mite allergen Der p 23 from Dermatophagoides pteronyssinus
Descriptor: 1,2-ETHANEDIOL, Dust mite allergen
Authors:Pedersen, L.C, Mueller, G.A, Randall, T.A, Glesner, J, Perera, L, Edwards, L.L, Chapman, M.D, London, R.E, Pomes, A.
Deposit date:2015-04-15
Release date:2015-11-25
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Serological, genomic and structural analyses of the major mite allergen Der p 23.
Clin Exp Allergy, 46, 2016
7MLH
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BU of 7mlh by Molmil
Crystal structure of human IgE (2F10) in complex with Der p 2.0103
Descriptor: CHLORIDE ION, Der p 2 variant 3, IgE Heavy chain, ...
Authors:Khatri, K, Kapingidza, A.B, Richardson, C.M, Vailes, L.D, Wunschmann, S, Dolamore, C, Chapman, M.D, Smith, S.A, Pomes, A, Chruszcz, M.
Deposit date:2021-04-28
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo.
Pnas Nexus, 1, 2022
4RLD
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BU of 4rld by Molmil
Crystal structure of kkf mutant of bla G 2 protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aspartic protease Bla g 2, ZINC ION
Authors:Li, M, Gustchina, A, Pomes, A, Wlodawer, A.
Deposit date:2014-10-16
Release date:2015-10-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:to be determined
To be Published
3LIZ
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BU of 3liz by Molmil
crystal structure of bla g 2 complexed with Fab 4C3
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C3 monoclonal antibody Heavy Chain, ...
Authors:Li, M, Gustchina, A, Glesner, J, Wunschmann, S, Pomes, A, Wlodawer, A.
Deposit date:2010-01-25
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding.
Plos One, 6, 2011
6OY4
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BU of 6oy4 by Molmil
Crystal structure of complex between recombinant Der p 2.0103 and Fab fragment of 7A1
Descriptor: Der p 2 variant 3, Fab fragment of IgG, HEAVY CHAIN, ...
Authors:Kapingidza, A.B, Offermann, L.R, Glesner, J, Wunschmann, S, Vailes, L.D, Chapman, M.D.C, Pomes, A, Chruszcz, M.
Deposit date:2019-05-14
Release date:2019-08-28
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy.
J Immunol., 203, 2019
3RVT
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BU of 3rvt by Molmil
Structure of 4C1 Fab in P212121 space group
Descriptor: Fab fragment of 4C1 antibody - heavy chain, Fab fragment of 4C1 antibody - light chain
Authors:Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W.
Deposit date:2011-05-06
Release date:2012-01-11
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular determinants for antibody binding on group 1 house dust mite allergens.
J.Biol.Chem., 287, 2012
3RVU
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BU of 3rvu by Molmil
Structure of 4C1 Fab in C2221 space group
Descriptor: 4C1 Fab - heavy chain, 4C1 Fab - light chain
Authors:Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W.
Deposit date:2011-05-06
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular determinants for antibody binding on group 1 house dust mite allergens.
J.Biol.Chem., 287, 2012
3MQ1
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BU of 3mq1 by Molmil
Crystal Structure of Dust Mite Allergen Der p 5
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Mite allergen Der p 5, ...
Authors:Mueller, G.A, Gosavi, R.A, Krahn, J.M, Edwards, L.L, Cuneo, M.J, Glesner, J, Pomes, A, Chapman, M.D, London, R.E, Pedersen, L.C.
Deposit date:2010-04-27
Release date:2010-06-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Der p 5 crystal structure provides insight into the group 5 dust mite allergens.
J.Biol.Chem., 285, 2010
4OUO
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BU of 4ouo by Molmil
anti-Bla g 1 scFv
Descriptor: CHLORIDE ION, SULFATE ION, anti Bla g 1 scFv
Authors:Mueller, G.A, Ankney, J.A, Glesner, J, Khurana, T, Edwards, L.L, Pedersen, L.C, Perera, L, Slater, J.E, Pomes, A, London, R.E.
Deposit date:2014-02-18
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Characterization of an anti-Bla g 1 scFv: Epitope mapping and cross-reactivity.
Mol.Immunol., 59, 2014
4POZ
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BU of 4poz by Molmil
Fab fragment of Der p 1 specific antibody 10B9
Descriptor: heavy chain of Fab fragment of 10B9 antibody, light chain of Fab fragment of 10B9 antibody
Authors:Osinski, T, Majorek, K.A, Pomes, A, Offermann, L.R, Osinski, S, Glesner, J, Vailes, L.D, Chapman, M.D, Minor, W, Chruszcz, M.
Deposit date:2014-02-26
Release date:2015-04-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.
J. Immunol., 195, 2015
5VCO
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BU of 5vco by Molmil
THE CRYSTAL STRUCTURE OF DER P 1 ALLERGEN COMPLEXED WITH FAB FRAGMENT OF MAB 10B9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HEAVY CHAIN OF FAB FRAGMENT OF 10B9 ANTIBODY, ...
Authors:Osinski, T, Majorek, K.A, Pomes, A, Offermann, L.R, Osinski, S, Glesner, J, Vailes, L.D, Chapman, M.D, Minor, W, Chruszcz, M.
Deposit date:2017-03-31
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.
J. Immunol., 195, 2015
5VPH
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BU of 5vph by Molmil
CRYSTAL STRUCTURE OF DER P 1 COMPLEXED WITH FAB 4C1
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Der p 1 allergen, ...
Authors:Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W.
Deposit date:2017-05-05
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens.
J.Biol.Chem., 287, 2012
5VCN
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BU of 5vcn by Molmil
THE CRYSTAL STRUCTURE OF DER P 1 ALLERGEN COMPLEXED WITH FAB FRAGMENT OF MAB 5H8
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Osinski, T, Majorek, K.A, Pomes, A, Offermann, L.R, Osinski, S, Glesner, J, Vailes, L.D, Chapman, M.D, Minor, W, Chruszcz, M.
Deposit date:2017-03-31
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.
J. Immunol., 195, 2015
5VPK
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BU of 5vpk by Molmil
CRYSTAL STRUCTURE OF MITE ALLERGEN DER F 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Der f 1 variant, SULFATE ION
Authors:Chruszcz, M, Chapman, M.D, Vailes, L.D, Pomes, A, Minor, W.
Deposit date:2017-05-05
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures Of Mite Allergens Der F 1 And Der P 1 Reveal Differences In Surface-Exposed Residues That May Influence Antibody Binding
J.Mol.Biol., 386, 2009
5VPG
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BU of 5vpg by Molmil
CRYSTAL STRUCTURE OF DER P 1 COMPLEXED WITH FAB 4C1
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W.
Deposit date:2017-05-05
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens.
J.Biol.Chem., 287, 2012
5VPL
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BU of 5vpl by Molmil
CRYSTAL STRUCTURE OF DER F 1 COMPLEXED WITH FAB 4C1
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C1 - HEAVY CHAIN, ...
Authors:Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W.
Deposit date:2017-05-05
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens.
J.Biol.Chem., 287, 2012
3F5V
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BU of 3f5v by Molmil
C2 Crystal form of mite allergen DER P 1
Descriptor: CALCIUM ION, Der p 1 allergen, HEXAETHYLENE GLYCOL
Authors:Stura, E.A, Minor, W, Chruszcz, M, Saint Remy, J.M.
Deposit date:2008-11-04
Release date:2009-02-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface-exposed residues that may influence antibody binding.
J.Mol.Biol., 386, 2009
4JRB
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BU of 4jrb by Molmil
Structure of Cockroach Allergen Bla g 1 Tandem Repeat as a EGFP fusion
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CHLORIDE ION, DODECANE, ...
Authors:Mueller, G.A, Pedersen, L.C, Lih, F.B, Glesner, J, Moon, A.F, Chapman, M.D, Tomer, K, London, R.E.
Deposit date:2013-03-21
Release date:2013-07-24
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.414 Å)
Cite:The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment.
J.Allergy Clin.Immunol., 132, 2013
3H4Z
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BU of 3h4z by Molmil
Crystal Structure of an MBP-Der p 7 fusion protein
Descriptor: Maltose-binding periplasmic protein fused with Allergen DERP7, SODIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pedersen, L.C, Mueller, G.A, London, R.E.
Deposit date:2009-04-21
Release date:2010-03-31
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins.
J.Allergy Clin.Immunol., 125, 2010
8DB4
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BU of 8db4 by Molmil
Crystal structure of the peanut allergen Ara h 2 bound by two neutralizing antibodies 22S1 and 13T1
Descriptor: 1,2-ETHANEDIOL, 13T1 Heavy chain, 13T1 Light chain, ...
Authors:Min, J, Pedersen, L.C.
Deposit date:2022-06-14
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Immunotherapy-induced neutralizing antibodies disrupt allergen binding and sustain allergen tolerance in peanut allergy.
J.Clin.Invest., 133, 2023
8EPU
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BU of 8epu by Molmil
1.6 A crystal structure of the lipocalin dog allergen Can f 1 with the C118S mutation
Descriptor: Major allergen Can f 1
Authors:Min, J, Pedersen, L.C, Geoffrey, M.A.
Deposit date:2022-10-06
Release date:2023-04-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7.
Front Allergy, 4, 2023
8EPV
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BU of 8epv by Molmil
2.2 A crystal structure of the lipocalin cat allergen Fel d 7
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Fel d 7 allergen, ...
Authors:Min, J, Pedersen, L.C, Geoffrey, M.A.
Deposit date:2022-10-06
Release date:2023-04-05
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7.
Front Allergy, 4, 2023
8G4P
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BU of 8g4p by Molmil
Crystal structure of the peanut allergen Ara h 2 bound by two neutralizing antibodies 13T1 and 13T5
Descriptor: 1,2-ETHANEDIOL, 13T1 Fab light chain, 13T5 Fab heavy chain, ...
Authors:Pedersen, L.C, Mueller, G.A, Min, J.
Deposit date:2023-02-10
Release date:2023-12-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Design of an Ara h 2 hypoallergen from conformational epitopes.
Clin Exp Allergy, 54, 2024

 

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