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1LUD
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BU of 1lud by Molmil
SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES
Descriptor: 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Polshakov, V.I, Smirnov, E.G, Birdsall, B, Kelly, G, Feeney, J.
Deposit date:2002-05-22
Release date:2002-12-18
Last modified:2016-12-28
Method:SOLUTION NMR
Cite:NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH
J.Biomol.Nmr, 24, 2002
1BZF
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BU of 1bzf by Molmil
NMR SOLUTION STRUCTURE AND DYNAMICS OF THE COMPLEX OF LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE WITH THE NEW LIPOPHILIC ANTIFOLATE DRUG TRIMETREXATE, 22 STRUCTURES
Descriptor: DIHYDROFOLATE REDUCTASE, TRIMETREXATE
Authors:Polshakov, V.I, Birdsall, B, Frenkiel, T.A, Gargaro, A.R, Feeney, J.
Deposit date:1998-10-28
Release date:1999-05-18
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.
Protein Sci., 8, 1999
5LFY
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BU of 5lfy by Molmil
Zinc bound dimer of the fragment of human amyloid-beta peptide with Alzheimer's disease pathogenic Taiwanese mutation D7H
Descriptor: Amyloid beta A4 protein, ZINC ION
Authors:Polshakov, V.I, Mantsyzov, A.B, Kozin, S.A.
Deposit date:2016-07-05
Release date:2017-08-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Binuclear Zinc Interaction Fold Discovered in the Homodimer of Alzheimer's Amyloid-beta Fragment with Taiwanese Mutation D7H.
Angew. Chem. Int. Ed. Engl., 56, 2017
2LLX
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BU of 2llx by Molmil
Solution structure of the N-terminal domain of human polypeptide chain release factor eRF1
Descriptor: Eukaryotic peptide chain release factor subunit 1
Authors:Polshakov, V.I, Eliseev, B.D, Birdsall, B, Frolova, L.Y.
Deposit date:2011-11-18
Release date:2012-05-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure and dynamics in solution of the stop codon decoding N-terminal domain of the human polypeptide chain release factor eRF1.
Protein Sci., 21, 2012
1PS2
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BU of 1ps2 by Molmil
HIGH RESOLUTION NMR SOLUTION STRUCTURE OF HUMAN PS2, 19 STRUCTURES
Descriptor: PS2
Authors:Williams, M.A, Polshakov, V.I, Gargaro, A.R, Feeney, J.
Deposit date:1997-01-07
Release date:1997-07-07
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein.
J.Mol.Biol., 267, 1997
1YHO
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BU of 1yho by Molmil
Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures
Descriptor: 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Polshakov, V.I, Birdsall, B.
Deposit date:2005-01-10
Release date:2005-11-22
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH.
J.Biomol.Nmr, 33, 2005
5LGF
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BU of 5lgf by Molmil
Solution structure of the N-terminal domain of Ogataea polymorpha telomerase reverse transcriptase
Descriptor: Telomerase reverse transcriptase
Authors:Polshakov, V.I, Mantsyzov, A.B, Efimov, S.V.
Deposit date:2016-07-07
Release date:2017-07-19
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.
Nucleic Acids Res., 46, 2018
7QCB
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BU of 7qcb by Molmil
Williams-Beuren syndrome related methyltransferase WBSCR27 in complex with SAH
Descriptor: Methyltransferase-like 27, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Polshakov, V.I, Mariasina, S.S, Chang, C.-F, Efimov, S.V.
Deposit date:2021-11-23
Release date:2021-12-29
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function.
Front Mol Biosci, 9, 2022
7QCC
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BU of 7qcc by Molmil
Williams-Beuren syndrome related methyltransferase WBSCR27 in apo-form
Descriptor: Methyltransferase-like 27
Authors:Polshakov, V.I, Mariasina, S.S, Chang, C.-F.
Deposit date:2021-11-23
Release date:2021-12-29
Last modified:2022-07-20
Method:SOLUTION NMR
Cite:Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function.
Front Mol Biosci, 9, 2022
2L28
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BU of 2l28 by Molmil
Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers
Descriptor: Dihydrofolate reductase
Authors:Polshakov, V.I, Birdsall, B, Feeney, J.
Deposit date:2010-08-13
Release date:2011-04-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions.
Biochemistry, 50, 2011
2HM9
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BU of 2hm9 by Molmil
Solution structure of dihydrofolate reductase complexed with trimethoprim, 33 structures
Descriptor: 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, Dihydrofolate reductase
Authors:Polshakov, V.I, Birdsall, B.
Deposit date:2006-07-11
Release date:2007-06-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structures of apo L.casei dihydrofolate reductase and its complexes with trimethoprim and NADPH. Contributions to positive cooperative binding from ligand-induced refolding, conformational changes and interligand hydrophobic interactions
Biochemistry, 2011
2HST
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BU of 2hst by Molmil
Solution structure of the middle domain of human eukaryotic translation termination factor eRF1
Descriptor: Eukaryotic peptide chain release factor subunit 1
Authors:Polshakov, V.I, Birdsall, B, Kisselev, L.L.
Deposit date:2006-07-23
Release date:2007-06-26
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Eukaryotic class 1 translation termination factor eRF1 - the NMR structure and dynamics of the middle domain involved in triggering ribosome-dependent peptidyl-tRNA hydrolysis
Febs J., 274, 2007
2HQP
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BU of 2hqp by Molmil
Solution structure of L.casei dihydrofolate reductase complexed with NADPH, 32 structures
Descriptor: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Polshakov, V.I, Birdsall, B.
Deposit date:2006-07-19
Release date:2007-06-05
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structural insights into cooperative effects of ligand binding to L. casei dihydrofolate redutase
TO BE PUBLISHED
1AO8
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BU of 1ao8 by Molmil
DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES
Descriptor: DIHYDROFOLATE REDUCTASE, METHOTREXATE
Authors:Gargaro, A.R, Soteriou, A, Frenkiel, T.A, Bauer, C.J, Birdsall, B, Polshakov, V.I, Barsukov, I.L, Roberts, G.C.K, Feeney, J.
Deposit date:1997-07-22
Release date:1998-02-25
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.
J.Mol.Biol., 277, 1998
1DIS
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BU of 1dis by Molmil
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE
Descriptor: BRODIMOPRIM-4,6-DICARBOXYLATE, DIHYDROFOLATE REDUCTASE
Authors:Morgan, W.D, Birdsall, B, Polshakov, V.I, Sali, D, Kompis, I, Feeney, J.
Deposit date:1995-08-01
Release date:1995-11-14
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
1DIU
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BU of 1diu by Molmil
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE
Descriptor: BRODIMOPRIM-4,6-DICARBOXYLATE, DIHYDROFOLATE REDUCTASE
Authors:Morgan, W.D, Birdsall, B, Polshakov, V.I, Sali, D, Kompis, I, Feeney, J.
Deposit date:1995-08-01
Release date:1995-11-14
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
6Q44
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BU of 6q44 by Molmil
Est3 telomerase subunit in the yeast Hansenula polymorpha
Descriptor: Uncharacterized protein
Authors:Mantsyzov, A.B, Mariasina, S.S, Petrova, O.A, Efimov, S.V, Dontsova, O.A, Polshakov, V.I.
Deposit date:2018-12-05
Release date:2019-12-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Insights into the structure and function of Est3 from the Hansenula polymorpha telomerase.
Sci Rep, 10, 2020
2KTV
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BU of 2ktv by Molmil
Human eRF1 C-domain, "open" conformer
Descriptor: Eukaryotic peptide chain release factor subunit 1
Authors:Mantsyzov, A.B, Polshakov, V.I, Birdsall, B.
Deposit date:2010-02-09
Release date:2010-06-09
Last modified:2021-08-18
Method:SOLUTION NMR
Cite:NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor.
Febs J., 277, 2010
2KTU
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BU of 2ktu by Molmil
Human eRF1 C-domain, "closed" conformer
Descriptor: Eukaryotic peptide chain release factor subunit 1
Authors:Mantsyzov, A.B, Polshakov, V.I, Birdsall, B.
Deposit date:2010-02-09
Release date:2010-06-09
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:NMR assignments of the C-terminal domain of human polypeptide release factor eRF1.
Biomol.Nmr Assign., 1, 2007
2MGT
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BU of 2mgt by Molmil
Zinc induced dimer of the metal binding domain 1-16 of human amyloid beta-peptide with Alzheimer's disease pathogenic English mutation H6R
Descriptor: Amyloid beta A4 protein, ZINC ION
Authors:Polshakov, V, Istrate, A, Kozin, S.
Deposit date:2013-11-06
Release date:2014-11-12
Last modified:2020-01-01
Method:SOLUTION NMR
Cite:Interplay of histidine residues of the Alzheimer's disease A beta peptide governs its Zn-induced oligomerization.
Sci Rep, 6, 2016
5NPT
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BU of 5npt by Molmil
Structure of the N-terminal domain of the yeast telomerase reverse transcriptase
Descriptor: Telomerase reverse transcriptase
Authors:Rodina, E.V, Lebedev, A.A, Hakanpaa, J, Hackenberg, C, Petrova, O.A, Zvereva, M.I, Dontsova, O.A, Lamzin, V.S.
Deposit date:2017-04-18
Release date:2017-12-20
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.
Nucleic Acids Res., 46, 2018
1HI7
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BU of 1hi7 by Molmil
NMR SOLUTION STRUCTURE OF THE DISULPHIDE-LINKED HOMODIMER OF HUMAN TFF1, 10 STRUCTURES
Descriptor: PS2 PROTEIN
Authors:Williams, M.A, Feeney, J.
Deposit date:2001-01-03
Release date:2001-01-03
Last modified:2019-04-10
Method:SOLUTION NMR
Cite:The Solution Structure of the Disulphide-Linked Dimeric of the Human Trefoil Protein Tff1
FEBS Lett., 493, 2001
2LF1
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BU of 2lf1 by Molmil
Solution structure of L. casei dihydrofolate reductase complexed with NADPH, 30 structures
Descriptor: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Polshakov, V, Feeney, J, Birdsall, B, Kovalevskaya, N.
Deposit date:2011-06-28
Release date:2011-12-21
Method:SOLUTION NMR
Cite:NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions
Biochemistry, 50, 2011
2LI9
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BU of 2li9 by Molmil
Metal binding domain of rat beta-amyloid
Descriptor: Amyloid beta A4 protein, ZINC ION
Authors:Polshakov, V, Istrate, A, Kozin, S, Makarov, A.
Deposit date:2011-08-25
Release date:2012-01-18
Last modified:2012-03-21
Method:SOLUTION NMR
Cite:NMR solution structure of rat Abeta(1-16): toward understanding the mechanism of rats' resistance to Alzheimer's disease.
Biophys.J., 102, 2012
6Y6X
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BU of 6y6x by Molmil
Tetracenomycin X bound to the human ribosome
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Buschauer, R, Cheng, J, Berninghausen, O, Beckmann, R, Wilson, D.N.
Deposit date:2020-02-27
Release date:2020-07-08
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020

 

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