Author results

1B7D
  • Download 1b7d
  • View 1b7d
Molmil generated image of 1b7d
NEUROTOXIN (TS1) FROM BRAZILIAN SCORPION TITYUS SERRULATUS
Descriptor:PROTEIN (NEUROTOXIN TS1), PHOSPHATE ION
Authors:Polikarpov, I., Sanches Jr., M.S., Marangoni, S., Toyama, M.H., Teplyakov, A.
Deposit date:1999-01-21
Release date:1999-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal structure of neurotoxin Ts1 from Tityus serrulatus provides insights into the specificity and toxicity of scorpion toxins.
J.Mol.Biol., 290, 1999
1QLR
  • Download 1qlr
  • View 1qlr
Molmil generated image of 1qlr
CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF A HUMAN MONOCLONAL IGM COLD AGGLUTININ
Descriptor:IGM KAPPA CHAIN V-III (KAU COLD AGGLUTININ), IGM FAB REGION IV-J(H4)-C (KAU COLD AGGLUTININ), N-ACETYL-D-GLUCOSAMINE, ...
Authors:Carvalho, J.G., Cauerhff, A., Goldbaum, F., Leoni, J., Polikarpov, I.
Deposit date:1999-09-11
Release date:2000-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Three-Dimensional Structure of the Fab Fragment from a Human Igm Cold Agglutinin
J.Immunol., 165, 2000
1DI0
  • Download 1di0
  • View 1di0
Molmil generated image of 1di0
CRYSTAL STRUCTURE OF LUMAZINE SYNTHASE FROM BRUCELLA ABORTUS
Descriptor:LUMAZINE SYNTHASE, PHOSPHATE ION
Authors:Braden, B.C., Velikovsky, C.A., Cauerhff, A.A., Polikarpov, I., Goldbaum, F.A.
Deposit date:1999-11-28
Release date:2000-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Divergence in macromolecular assembly: X-ray crystallographic structure analysis of lumazine synthase from Brucella abortus.
J.Mol.Biol., 297, 2000
1IG8
  • Download 1ig8
  • View 1ig8
Molmil generated image of 1ig8
CRYSTAL STRUCTURE OF YEAST HEXOKINASE PII WITH THE CORRECT AMINO ACID SEQUENCE
Descriptor:hexokinase PII, SULFATE ION
Authors:Kuser, P.R., Krauchenco, S., Antunes, O.A., Polikarpov, I.
Deposit date:2001-04-17
Release date:2001-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The high resolution crystal structure of yeast hexokinase PII with the correct primary sequence provides new insights into its mechanism of action.
J.Biol.Chem., 275, 2000
1JV4
  • Download 1jv4
  • View 1jv4
Molmil generated image of 1jv4
CRYSTAL STRUCTURE OF RECOMBINANT MAJOR MOUSE URINARY PROTEIN (RMUP) AT 1.75 A RESOLUTION
Descriptor:Major urinary protein 2, CADMIUM ION, 2-(SEC-BUTYL)THIAZOLE
Authors:Kuser, P.R., Franzoni, L., Ferrari, E., Spisni, A., Polikarpov, I.
Deposit date:2001-08-28
Release date:2001-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-ray structure of a recombinant major urinary protein at 1.75 A resolution. A comparative study of X-ray and NMR-derived structures.
Acta Crystallogr.,Sect.D, 57, 2001
1M4R
  • Download 1m4r
  • View 1m4r
Molmil generated image of 1m4r
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-22
Descriptor:Interleukin-22
Authors:Nagem, R.A.P., Colau, D., Dumoutier, L., Renauld, J.-C., Ogata, C., Polikarpov, I.
Deposit date:2002-07-03
Release date:2003-07-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Recombinant Human Interleukin-22
Structure, 10, 2002
1NNS
  • Download 1nns
  • View 1nns
Molmil generated image of 1nns
L-ASPARAGINASE OF E. COLI IN C2 SPACE GROUP AND 1.95 A RESOLUTION
Descriptor:L-asparaginase II, ASPARTIC ACID
Authors:Sanches, M., Barbosa, J.A.R.G., de Oliveira, R.T., Neto, J.A.A., Polikarpov, I.
Deposit date:2003-01-14
Release date:2003-03-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural comparison of Escherichia coli L-asparaginase in two monoclinic space groups.
Acta Crystallogr.,Sect.D, 59, 2003
1NPI
  • Download 1npi
  • View 1npi
Molmil generated image of 1npi
TITYUS SERRULATUS NEUROTOXIN (TS1) AT ATOMIC RESOLUTION
Descriptor:Toxin VII, PHOSPHATE ION
Authors:Pinheiro, C.B., Marangoni, S., Toyama, M.H., Polikarpov, I.
Deposit date:2003-01-17
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structural analysis of Tityus serrulatus Ts1 neurotoxin at atomic resolution: insights into interactions with Na+ channels.
Acta Crystallogr.,Sect.D, 59, 2003
1R2R
  • Download 1r2r
  • View 1r2r
Molmil generated image of 1r2r
CRYSTAL STRUCTURE OF RABBIT MUSCLE TRIOSEPHOSPHATE ISOMERASE
Descriptor:Triosephosphate isomerase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
Authors:Aparicio, R., Ferreira, S.T., Polikarpov, I.
Deposit date:2003-09-29
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Closed conformation of the active site loop of rabbit muscle triosephosphate isomerase in the absence of substrate: evidence of conformational heterogeneity.
J.Mol.Biol., 334, 2003
1R2S
  • Download 1r2s
  • View 1r2s
Molmil generated image of 1r2s
CRYSTAL STRUCTURE OF RABBIT MUSCLE TRIOSEPHOSPHATE ISOMERASE
Descriptor:Triosephosphate isomerase
Authors:Aparicio, R., Ferreira, S.T., Polikarpov, I.
Deposit date:2003-09-29
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Closed conformation of the active site loop of rabbit muscle triosephosphate isomerase in the absence of substrate: evidence of conformational heterogeneity.
J.Mol.Biol., 334, 2003
1R2T
  • Download 1r2t
  • View 1r2t
Molmil generated image of 1r2t
CRYSTAL STRUCTURE OF RABBIT MUSCLE TRIOSEPHOSPHATE ISOMERASE
Descriptor:Triosephosphate isomerase
Authors:Aparicio, R., Ferreira, S.T., Polikarpov, I.
Deposit date:2003-09-29
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Closed conformation of the active site loop of rabbit muscle triosephosphate isomerase in the absence of substrate: evidence of conformational heterogeneity.
J.Mol.Biol., 334, 2003
1R8N
  • Download 1r8n
  • View 1r8n
Molmil generated image of 1r8n
THE CRYSTAL STRUCTURE OF THE KUNITZ (STI) TYPE INHIBITOR FROM SEEDS OF DELONIX REGIA
Descriptor:Kunitz trypsin inhibitor
Authors:Krauchenco, S., Pando, S.C., Marangoni, S., Polikarpov, I.
Deposit date:2003-10-27
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the Kunitz (STI)-type inhibitor from Delonix regia seeds.
Biochem.Biophys.Res.Commun., 312, 2003
1R8O
  • Download 1r8o
  • View 1r8o
Molmil generated image of 1r8o
CRYSTAL STRUCTURE OF AN UNUSUAL KUNITZ-TYPE TRYPSIN INHIBITOR FROM COPAIFERA LANGSDORFFII SEEDS
Descriptor:Kunitz trypsin inhibitor
Authors:Krauchenco, S., Nagem, R.A.P., da Silva, J.A., Marangoni, S., Polikarpov, I.
Deposit date:2003-10-27
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Three-dimensional structure of an unusual Kunitz (STI) type trypsin inhibitor from Copaifera langsdorffii.
Biochimie, 86, 2004
1TG7
  • Download 1tg7
  • View 1tg7
Molmil generated image of 1tg7
NATIVE STRUCTURE OF BETA-GALACTOSIDASE FROM PENICILLIUM SP.
Descriptor:beta-galactosidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Rojas, A.L., Nagem, R.A.P., Neustroev, K.N., Arand, M., Adamska, M., Eneyskaya, E.V., Kulminskaya, A.A., Garratt, R.C., Golubev, A.M., Polikarpov, I.
Deposit date:2004-05-28
Release date:2004-11-02
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of beta-Galactosidase from Penicillium sp. and its Complex with Galactose
J.Mol.Biol., 343, 2004
1XC6
  • Download 1xc6
  • View 1xc6
Molmil generated image of 1xc6
NATIVE STRUCTURE OF BETA-GALACTOSIDASE FROM PENICILLIUM SP. IN COMPLEX WITH GALACTOSE
Descriptor:Beta-Galactosidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Rojas, A.L., Nagem, R.A.P., Neustroev, K.N., Arand, M., Adamska, M., Eneyskaya, E.V., Kulminskaya, A.A., Garratt, R.C., Golubev, A.M., Polikarpov, I.
Deposit date:2004-09-01
Release date:2004-11-02
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of beta-Galactosidase from Penicillium sp. and its Complex with Galactose
J.Mol.Biol., 343, 2004
1Y4W
  • Download 1y4w
  • View 1y4w
Molmil generated image of 1y4w
CRYSTAL STRUCTURE OF EXO-INULINASE FROM ASPERGILLUS AWAMORI IN SPACEGROUP P21
Descriptor:exo-inulinase, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:Nagem, R.A.P., Rojas, A.L., Golubev, A.M., Korneeva, O.S., Eneyskaya, E.V., Kulminskaya, A.A., Neustroev, K.N., Polikarpov, I.
Deposit date:2004-12-01
Release date:2004-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of exo-inulinase from Aspergillus awamori: the enzyme fold and structural determinants of substrate recognition
J.Mol.Biol., 344, 2004
1Y9G
  • Download 1y9g
  • View 1y9g
Molmil generated image of 1y9g
CRYSTAL STRUCTURE OF EXO-INULINASE FROM ASPERGILLUS AWAMORI COMPLEXED WITH FRUCTOSE
Descriptor:exo-inulinase, N-ACETYL-D-GLUCOSAMINE, FRUCTOSE
Authors:Nagem, R.A.P., Rojas, A.L., Golubev, A.M., Korneeva, O.S., Eneyskaya, E.V., Kulminskaya, A.A., Neustroev, K.N., Polikarpov, I.
Deposit date:2004-12-15
Release date:2004-12-21
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structure of exo-inulinase from Aspergillus awamori: the enzyme fold and structural determinants of substrate recognition
J.Mol.Biol., 344, 2004
1Y9M
  • Download 1y9m
  • View 1y9m
Molmil generated image of 1y9m
CRYSTAL STRUCTURE OF EXO-INULINASE FROM ASPERGILLUS AWAMORI IN SPACEGROUP P212121
Descriptor:exo-inulinase, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Nagem, R.A.P., Rojas, A.L., Golubev, A.M., Korneeva, O.S., Eneyskaya, E.V., Kulminskaya, A.A., Neustroev, K.N., Polikarpov, I.
Deposit date:2004-12-16
Release date:2004-12-28
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structure of exo-inulinase from Aspergillus awamori: the enzyme fold and structural determinants of substrate recognition
J.Mol.Biol., 344, 2004
2P3A
  • Download 2p3a
  • View 2p3a
Molmil generated image of 2p3a
CRYSTAL STRUCTURE OF THE MULTI-DRUG RESISTANT MUTANT SUBTYPE B HIV PROTEASE COMPLEXED WITH TL-3 INHIBITOR
Descriptor:protease, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate
Authors:Sanches, M., Krauchenco, S., Martins, N.H., Gustchina, A., Wlodawer, A., Polikarpov, I.
Deposit date:2007-03-08
Release date:2007-04-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Characterization of B and non-B Subtypes of HIV-Protease: Insights into the Natural Susceptibility to Drug Resistance Development.
J.Mol.Biol., 369, 2007
2P3B
  • Download 2p3b
  • View 2p3b
Molmil generated image of 2p3b
CRYSTAL STRUCTURE OF THE SUBTYPE B WILD TYPE HIV PROTEASE COMPLEXED WITH TL-3 INHIBITOR
Descriptor:protease, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate
Authors:Sanches, M., Krauchenco, S., Martins, N.H., Gustchina, A., Wlodawer, A., Polikarpov, I.
Deposit date:2007-03-08
Release date:2007-04-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Characterization of B and non-B Subtypes of HIV-Protease: Insights into the Natural Susceptibility to Drug Resistance Development.
J.Mol.Biol., 369, 2007
2P3C
  • Download 2p3c
  • View 2p3c
Molmil generated image of 2p3c
CRYSTAL STRUCTURE OF THE SUBTYPE F WILD TYPE HIV PROTEASE COMPLEXED WITH TL-3 INHIBITOR
Descriptor:protease, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate, ACETIC ACID
Authors:Sanches, M., Krauchenco, S., Martins, N.H., Gustchina, A., Wlodawer, A., Polikarpov, I.
Deposit date:2007-03-08
Release date:2007-04-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Characterization of B and non-B Subtypes of HIV-Protease: Insights into the Natural Susceptibility to Drug Resistance Development.
J.Mol.Biol., 369, 2007
2P3D
  • Download 2p3d
  • View 2p3d
Molmil generated image of 2p3d
CRYSTAL STRUCTURE OF THE MULTI-DRUG RESISTANT MUTANT SUBTYPE F HIV PROTEASE COMPLEXED WITH TL-3 INHIBITOR
Descriptor:Pol protein, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate
Authors:Sanches, M., Krauchenco, S., Martins, N.H., Gustchina, A., Wlodawer, A., Polikarpov, I.
Deposit date:2007-03-08
Release date:2007-04-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Characterization of B and non-B Subtypes of HIV-Protease: Insights into the Natural Susceptibility to Drug Resistance Development.
J.Mol.Biol., 369, 2007
3NEE
  • Download 3nee
  • View 3nee
Molmil generated image of 3nee
WILD TYPE HUMAN TRANSTHYRETIN (TTR) COMPLEXED WITH GC-1 (TTRWT:GC-1)
Descriptor:Transthyretin, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid, GLYCEROL
Authors:Trivella, D.B.B., Polikarpov, I.
Deposit date:2010-06-08
Release date:2010-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J.Struct.Biol., 173, 2011
4H7M
  • Download 4h7m
  • View 4h7m
Molmil generated image of 4h7m
THE X-RAY CRYSTAL STRUCTURE OF THE TRICHODERMA HARZIANUM ENDOGLUCANASE 3 FROM FAMILY GH12
Descriptor:Endo-1,4-beta-glucanase
Authors:Liberato, M.V., Polikarpov, I.
Deposit date:2012-09-20
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.068 Å)
Cite:X-ray Structure and Molecular Dynamics Simulations of Endoglucanase 3 from Trichoderma harzianum: Structural Organization and Substrate Recognition by Endoglucanases That Lack Cellulose Binding Module.
Plos One, 8, 2013
4TUF
  • Download 4tuf
  • View 4tuf
Molmil generated image of 4tuf
CATALYTIC DOMAIN OF THE MAJOR ENDOGLUCANASE FROM XANTHOMONAS CAMPESTRIS PV. CAMPESTRIS
Descriptor:Major extracellular endoglucanase, DIHYDROGENPHOSPHATE ION
Authors:Puhl, A.C., Rosseto, F.R., Polikarpov, I.
Deposit date:2014-06-24
Release date:2015-10-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Substrate cleavage pattern, biophysical characterization and crystallographic structure of the major endoglucanase from Xanthomonas campestris pv. campestris
To Be Published